Results 41 to 50 of about 1,875,854 (282)
Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PD-L1 expression and presence of CD8+ tumor infiltrating lymphocytes. [PDF]
, 2016 BackgroundMalignant peripheral nerve sheath tumor (MPNST) is an aggressive sarcoma with few treatment options. Tumor immune state has not been characterized in MPNST, and is important in determining response to immune checkpoint blockade.
Bernthal, Nicholas +11 more
core +2 more sources
The Elasticity-Based Approach to Enterprise Innovation
International Journal of Management and Economics, 2016 The goal of this paper is to present a formal model of firm innovation that simultaneously analyzes innovation factors characteristic to the Schumpeterian strand of industrial organization literature and the know-how strand.
Karbowski Adam
doaj +1 more source
ACM Transactions on Architecture and Code Optimization, 2014 Research has shown that operating in the near-threshold region is expected to provide up to 10× energy efficiency for future processors. However, reliable operation below a minimum voltage (Vccmin) cannot be guaranteed due to process variations. Because SRAM margins can easily be violated at near-threshold voltages, their bit-cell failure rates are ...
Farrukh Hijaz, Omer Khan
openaire +1 more source
Is Galactic Star Formation Activity Increased During Cluster Mergers? [PDF]
, 1999 We have investigated the effect of pressure from intracluster medium (ICM) on disk galaxies in merging clusters. The ram-pressure on the galaxies rapidly increases when two clusters collide.
Enoki, Motohiro +3 more
core +3 more sources
Clinical Insights Into Hypercalcemia of Malignancy in Childhood
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul +13 more
wiley +1 more source
Journal of Bone Oncology, 2019 Chondrosarcomas are malignant cartilage tumors that are relatively resistant towards conventional therapeutic approaches. Kinase inhibitors have been investigated and shown successful for several different cancer types.
Yvonne de Jong +13 more
doaj +1 more source
Semantic access in number word translation - The role of crosslingual lexical similarity [PDF]
, 2008 The revised hierarchical model of bilingualism (e.g., Kroll & Stewart, 1994) assumes that second language (1,2) words primarily access semantics through their first language (L1) translation equivalents.
Brysbaert, Marc, Duyck, Wouter
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source