Results 161 to 170 of about 34,982 (314)

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu   +4 more
wiley   +1 more source

Dual‐Mode Electrophoretic Displays Enabled by Quantum Dot‐Decorated PR48:2 Pigment Particles and TiO2 for All‐Weather Visibility, Excellent Bistability, and Enhanced Readability

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study presents a novel quantum dot electrophoretic display (QDEPD), which combines electro‐controlled reflection and optically‐triggered emission to achieve efficient multi‐modal switching within a single pixel. By incorporating multi‐component nanostructures, the system enhances functional integration and multi‐modal response capabilities.
Xingke Zheng   +8 more
wiley   +1 more source

Integrating multivariate resting‐state fMRI features to localize epileptic networks in common childhood epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Accurate localization of epileptic activity remains challenging when interictal discharges are absent or sparse. Although resting‐state functional MRI (rs‐fMRI) is noninvasive, individual rs‐fMRI metrics provide inconsistent and incomplete localization.
Qirui Zhang   +8 more
wiley   +1 more source

Mindfulness meditation increases interictal epileptiform discharges in meditation‐naïve surgical epilepsy patients

open access: yesEpilepsia, EarlyView.
Abstract Objective Meditation has widely recognized psychological and neuromodulatory benefits, yet its effects on epileptiform activity remain unclear. This study examined whether novice meditation modulates interictal epileptiform discharges (IEDs) in patients with drug‐resistant epilepsy using intracranial electroencephalography (iEEG).
Shweta Soni   +5 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Extensive reading as a breakthrough in a traditional EFL curriculum: experimental research in junior high schools in Taiwan [PDF]

open access: yes
The main focus of this research was to examine the effects of extensive reading on junior high school students' language proficiency and learning attitude development, compared with those who received the current reading IR (grammar/translation-based ...
Sheu, Ping-Huang
core  

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

open access: yesEpilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

AI‐based localization of the epileptogenic zone using intracranial EEG

open access: yesEpilepsia Open, EarlyView.
Abstract Artificial intelligence (AI) is rapidly transforming our lives. Machine learning (ML) enables computers to learn from data and make decisions without explicit instructions. Deep learning (DL), a subset of ML, uses multiple layers of neural networks to recognize complex patterns in large datasets through end‐to‐end learning.
Atsuro Daida   +5 more
wiley   +1 more source

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