Results 181 to 190 of about 34,982 (314)

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

open access: yesiNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu   +5 more
wiley   +1 more source

L1 and L2 Contributions to English Reading in Middle School Struggling Readers. [PDF]

open access: yesBiling (Camb Engl)
Cirino PT   +4 more
europepmc   +1 more source

A dendrimer enhanced CRISPR/Cas12a performance for the evaluation of acidogenic capacity in cariogenic bacteria

open access: yesInterdisciplinary Medicine, EarlyView.
A CRISPR/Cas12a‐powered dendritic DNA nanostructure is assembled to create confined enzymatic microdomains, enabling ultrasensitive detection. Integrated into a paper‐based origami biosensor, it allows equipment‐free on‐site quantification of acidogenic pathogens for the early diagnosis of dental caries.
Yuan Zhang   +4 more
wiley   +1 more source

Ordered assembly of Cas12a for better performance of CRISPR/Cas system with application to the diagnosis of dental caries

open access: yesInterdisciplinary Medicine, EarlyView.
Here, we present a tetrahedral DNA framework (TDF)‐mediated Cas12a ordered assembly strategy. TDFs arrange CRISPR/Cas12a into ordered structures controllably, enhancing catalytic efficiency through localized Cas12a hotspots while maintaining spatial intervals to facilitate substrate diffusion.
Yining Zhao   +6 more
wiley   +1 more source

Machine Learning‐Based Estimation of Reference Evapotranspiration and Crop Coefficients for Wheat Under Diverse Climatic Conditions

open access: yesIrrigation and Drainage, EarlyView.
ABSTRACT Accurate estimation of reference evapotranspiration (ET0) and crop coefficients (Kc) is critical for irrigation planning, particularly in data‐limited regions where agriculture dominates freshwater consumption. Although machine learning (ML) methods have been widely applied to ET0 and Kc estimation, most studies address these parameters ...
Ilker Angin   +4 more
wiley   +1 more source

AI‐Powered Gradient Echo Plural Contrast Imaging (AI‐GEPCI)—A Comprehensive Neurological Protocol From a Single MRI Scan

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background MRI is essential for diagnosing and monitoring neurological diseases. Conventional protocols require multiple sequences to obtain complementary contrasts, increasing scan time, cost, and tolerability. Generating multiple contrasts from a single acquisition may streamline workflow while maintaining clinical utility.
Jeramy Lewis   +8 more
wiley   +1 more source

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