Results 51 to 60 of about 5,419 (209)

Scaling Up Organic Agricultural Enterprises: An Empirical Study of the Role of Associations of Micro Producers

Business Systems Research
Development of organic agricultural entrepreneurship often requires “scaling up” from a multitude of individual, largely disconnected micro organic enterprises with haphazard achievements, toward more integrated units, operating more systematically and ...
Božić Jasmina
doaj   +1 more source

Lección 31. Empleados públicos

Revista de Derecho Público, 2023
SUMARIO: 1. LOS DIVERSOS MODELOS DE EMPLEO PÚBLICO: 1.1. Breve repaso a la evolución histórica del modelo de empleo público en España y consagración del principio de mérito y capacidad; 1.2.
Andrés Boix Palop
doaj   +1 more source

MrpL36p, a Highly Diverged L31 Ribosomal Protein Homolog With Additional Functional Domains in Saccharomyces cerevisiae Mitochondria [PDF]

Genetics, 2004
Abstract Translation in mitochondria utilizes a large complement of ribosomal proteins. Many mitochondrial ribosomal components are clearly homologous to eubacterial ribosomal proteins, but others appear unique to the mitochondrial system.
Elizabeth H, Williams, Xochitl, Perez-Martinez, Thomas D, Fox   +2 more
openaire   +2 more sources

Evaluation of Resistance-Associated Substitutions in NS5A Using Direct Sequence and Cycleave Method and Treatment Outcome with Daclatasvir and Asunaprevir for Chronic Hepatitis C Genotype 1. [PDF]

PLoS ONE, 2016
The aim of this study was to evaluate the efficacy of daclatasvir plus asunaprevir therapy in patients infected with hepatitis C virus and determine its relevance to resistant variants.A total of 629 consecutive patients infected with hepatitis C virus ...
Tatsuya Ide, Yuichiro Eguchi, Masaru Harada, Kunihide Ishii, Masaru Morita, Yasuyo Morita, Gen Sugiyama, Hirofumi Fukushima, Yoichi Yano, Kazunori Noguchi, Hiroki Nakamura, Junjiro Hisatomi, Hiroto Kumemura, Miki Shirachi, Shinji Iwane, Michiaki Okada, Yuichi Honma, Teruko Arinaga-Hino, Ichiro Miyajima, Kei Ogata, Reiichiro Kuwahara, Keisuke Amano, Toshihiro Kawaguchi, Ryoko Kuromatsu, Takuji Torimura, DAAs Multicenter Study Group   +25 more
doaj   +1 more source

Effects of sociocultural and economic factors on social entrepreneurship and sustainable development

Journal of Innovation & Knowledge, 2021
Concern about environmental problems has led to more attention being paid to the sustainable development objective. Social entrepreneurship, and entrepreneurship in general, show a direct relationship with this objective, due mainly to the activities ...
María-Teresa Méndez-Picazo, Miguel-Angel Galindo-Martín, María-Soledad Castaño-Martínez   +2 more
doaj   +1 more source

Prevalence of other RASs within NS5A in combination with signature L31/Y93 RAS.

, 2016
Other RAS in combination with dual signature RAS (L31-RAS/Y93-RAS) were detected in 53% of patients. The prevalences of triple, quadruple, and quintuple RAS were 38%, 13%, and 2%, respectively.
Miyako Murakawa (3239484), Takehiko Abe (3239505), Jun Itakura (554845), Shinya Sakita (3239508), Yasushi Ide (3239511), Masayuki Kurosaki (156560), Kouji Joko (3239496), Takashi Satou (3239469), Chikara Ogawa (3239478), Namiki Izumi (156627), Keiji Tsuji (3239502), Haruhiko Kobashi (3239490), Nobuyuki Enomoto (92837), Syotaro Tsuruta (3239475), Akeri Mitsuda (3239472), Yukio Osaki (170808), Kouichi Takaguchi (3239481), Hiroaki Okushin (3239499), Takashi Tamada (204139), Hiroyuki Hisai (3239493), Chitomi Hasebe (3239487), Hitoshi Yagisawa (147721), Yasuhiro Asahina (156563)   +22 more
core   +1 more source

Inhibition of TLR4 signaling protects mice from sensory and motor dysfunction in an animal model of autoimmune peripheral neuropathy

Journal of Neuroinflammation, 2021
Background While the etiology remains elusive, macrophages and T cells in peripheral nerves are considered as effector cells mediating autoimmune peripheral neuropathy (APN), such as Guillain-Barre syndrome.
Oladayo Oladiran, Xiang Qun Shi, Mu Yang, Sylvie Fournier, Ji Zhang   +4 more
doaj   +1 more source

Selective modulation of NaV channel gating counteracts aberrant hyperexcitability and rescues motor function and survival in a model of spinal muscular atrophy

British Journal of Pharmacology, EarlyView.
Background and Purpose Spinal muscular atrophy (SMA) is a motor neuron disease caused by SMN1 gene loss, leading to reduced survival motor neuron (SMN) protein and progressive motor neuron degeneration. Although SMN‐restoring therapies improve outcomes, residual disease burden and non‐curative efficacy underscore the need for complementary treatments ...
Fernanda C. Cardoso, Jessica A. I. Muller, Yougang Zhang, Jean Giacomotto   +3 more
wiley   +1 more source

Sequence requirement for nucleolar localization of rat ribosomal protein L31

European journal of cell biology, 1997
Nucleolar localization of the fusion protein of rat ribosomal protein L31 and beta-galactosidase was investigated by immunocytochemical means, using the ribosomal protein deletion or substitution mutants that were transiently expressed in COS-1 cells.
I K, Quaye, S, Toku, T, Tanaka
openaire   +3 more sources

Bibliometric analysis of social enterprise literature: Revisit to regroup

Journal of Innovation & Knowledge, 2023
Social enterprise (SE) studies are gaining ground as an emerging research domain owing to the duality characterizing their business models for tapping the triple bottom line (TBL) principle, which is a framework measuring the three pillars of ...
Hisyam, Shi-Woei Lin
doaj   +1 more source