Results 101 to 110 of about 261,108 (323)

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Traffic characteristics analysis in optical burst switching networks with optical label processing

open access: yesSemina: Ciências Exatas e Tecnológicas, 2007
An analysis is carried out with burst-switching optical networks which use label processing consisting of orthogonal optical codes (OOC), considering traffic characteristics such as length/duration and arrival rate of bursts.
Edson Moschim   +3 more
doaj  

Service model of the voice traffic in multiprotocol label switching networks [PDF]

open access: yes, 2013
This paper proposes and investigates a service model of the voice traffic in multiprotocol label switching networks. The study of Multiprotocol label switching networks (MPLS) requires a formal description of processes occurring in them, development of ...
Mankovskiy, Volodymyr B.   +1 more
core  

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Predictors of switching antipsychotic medications in the treatment of schizophrenia

open access: yesBMC Psychiatry, 2010
Background To identify patient characteristics and early changes in patients' clinical status that best predict subsequent switching of antipsychotic agents in the long-term treatment of schizophrenia.
Stauffer Virginia L   +4 more
doaj   +1 more source

THE EFFECT OF NEW FOOD LABELING ON NUTRIENT INTAKES: AN ENDOGENOUS SWITCHING REGRESSION ANALYSIS [PDF]

open access: yes
This paper examines the effect of the new labeling regulations on nutrient intakes using an endogenous switching regression model. Using the 1994 - 96 CSFII/DHKS, we evaluate the impact of food label use on intakes of selected nutrients.Food Consumption ...
Capps, Oral, Jr.   +2 more
core   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Liver‐specific lncRNAs associated with liver cancers

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina   +3 more
wiley   +1 more source

Effect of CYP2C19 status on platelet reactivity in Taiwanese acute coronary syndrome patients switching to prasugrel from clopidogrel: Switch Study

open access: yesJournal of the Formosan Medical Association, 2022
Background/Purpose: Pharmacogenetics is a potential driver of the “East Asian paradox,” in which East Asian acute coronary syndrome (ACS) patients receiving dual antiplatelet therapy (DAPT) with clopidogrel following percutaneous coronary intervention ...
Feng-Yu Kuo   +15 more
doaj  

Switching from conventional to extrafine aerosol beclomethasone dipropionate therapy in children: A 6-month, open- label, randomized trial [PDF]

open access: bronze, 2002
Stanley J. Szefler   +7 more
openalex   +1 more source

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