Results 101 to 110 of about 2,857,921 (357)
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova+18 more
wiley +1 more source
Tremor is a common side effect of tacrolimus correlated with peak‐dose drug concentration. LCPT, a novel, once‐daily, extended‐release formulation of tacrolimus, has a reduced Cmax with comparable AUC exposure, requiring a ~30% dose reduction vs ...
A. Langone+15 more
semanticscholar +1 more source
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop+10 more
wiley +1 more source
Performance Of Optical Label Switching Network With Multi Protocol Label Switching Implementation [PDF]
Today, the phenomenal traffic growth of Internet leads to the dramatic expansion of the transmission lines in the Internet Protocol (IP) network. Fibre optics as the key of the future transmission networks has evolved to provide almost limitless ...
Kaspin, Rizaludin
core
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
THE EFFECT OF NEW FOOD LABELING ON NUTRIENT INTAKES: AN ENDOGENOUS SWITCHING REGRESSION ANALYSIS [PDF]
This paper examines the effect of the new labeling regulations on nutrient intakes using an endogenous switching regression model. Using the 1994 - 96 CSFII/DHKS, we evaluate the impact of food label use on intakes of selected nutrients.Food Consumption ...
Capps, Oral, Jr.+2 more
core +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche+8 more
wiley +1 more source
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source
To assess the safety and efficacy of rilpivirine in combination with emtricitabine and tenofovir (RPV/FTC/TDF) as a once-daily single-tablet regimen (STR) in HIV-1-infected children and adolescents we performed a multicenter case series study of HIV-1 ...
Lola Falcón-Neyra+14 more
semanticscholar +1 more source
The Design and Implementation of a PCIe-based LESS Label Switch [PDF]
With the explosion of the Internet of Things, the number of smart, embedded devices has grown exponentially in the last decade, with growth projected at a commiserate rate.
Williams, Amy C
core +1 more source