Results 71 to 80 of about 2,939,424 (357)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Simulasi Multi Protocol Label Switching Virtual Private Network (MPLS VPN) Dengan Virtual Local Area Network (VLAN) Menggunakan Router MIKROTIK [PDF]

, 2018
Untuk mendapatkan komunikasi yang cepat, aman, dan mudah diakses digunakan jaringan MPLS VPN menggunakan VLAN. Jaringan MPLS akan mengirimkan paket sesuai dengan label yang ada pada header paket ke tujuan yang diinginkan dan VPN akan membatasi siapa ...
Euginia, B. (Bertha), Ghozali, T. (Theresia)   +1 more
core  

Implementation of Dual-fordwarding-plane Intelligent Path Selection based on SRv6+ MPLS

Guangtongxin yanjiu, 2022
Under the background of the long-term coexistence of the 4th and 5th Generation Mobile Communication Technology (4G and 5G), as the Segment Routing (SRv6) protocol standard based on the Internet Protocol version 6 (IPv6) forwarding plane is basically ...
Pei-yong MA, Guang-ming YANG, Dong-feng MAO, Yu-juan LI   +3 more
doaj   +1 more source

Evaluation of Biomarkers of Exposure in Smokers Switching to a Carbon-Heated Tobacco Product: A Controlled, Randomized, Open-Label 5-Day Exposure Study

Nicotine & Tobacco Research, 2016
Introduction: Tobacco harm reduction aims to provide reduced risk alternatives to adult smokers who would otherwise continue smoking combustible cigarettes (CCs).
F. Lüdicke, C. Haziza, R. Weitkunat, J. Magnette   +3 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

On the edge-balanced index sets of product graphs [PDF]

, 2011
We characterize strongly edge regular product graphs and find the edge-balanced index sets of complete bipartite graphs without a perfect matching, the direct product $K_n\times K_2$.
Krop, Elliot, Lee, Sin-Min, Raridan, Christopher   +2 more
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Real-World Efficacy and Safety of Tafluprost in Primary Open-Angle Glaucoma Patients with Corneal Disorders: A Taiwan Experience

Journal of Ophthalmology, 2022
Purpose. To investigate the efficacy and safety of switching to 0.0015% tafluprost ophthalmic solution with reduced benzalkonium chloride (BAK) on primary open-angle glaucoma (POAG) patients with corneal disorders under 0.005% latanoprost treatment ...
Ju-Kuo Lin, Fu-Tsung Wei, Yi-Chun Liu, Yung-Chang Yen   +3 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Performance evaluation of MPLS-enabled communications infrastructure for wide area monitoring systems [PDF]

, 2015
In order to obtain the transient power system measurement information, Wide Area Monitoring Systems (WAMS) should be able to collect Phasor Measurement Unit (PMU) data in a timely manner.
Ashton, PM, Golshani, M, Pisica, I, Taylor, GA   +3 more
core   +1 more source