Results 81 to 90 of about 278,707 (295)

THE EFFECT OF NEW FOOD LABELING ON NUTRIENT INTAKES: AN ENDOGENOUS SWITCHING REGRESSION ANALYSIS [PDF]

open access: yes
This paper examines the effect of the new labeling regulations on nutrient intakes using an endogenous switching regression model. Using the 1994 - 96 CSFII/DHKS, we evaluate the impact of food label use on intakes of selected nutrients.Food Consumption ...
Capps, Oral, Jr.   +2 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

THE EFFECT OF FOOD LABEL USE ON NUTRIENT INTAKES: AN ENDOGENOUS SWITCHING REGRESSION ANALYSIS [PDF]

open access: yes
This study examines the impact of consumers'Â’ use of food labels on selected nutrient intakes of Americans. Endogenous switching regression techniques are employed to control for heterogeneity in the label use decision.
Capps, Oral, Jr.   +2 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Study of FEC at edge node of optical code label switching network

open access: yesTongxin xuebao, 2012
The structure block of the optical code label switching network was built,and the design scheme for the forwarding equivalent classes (FEC)was proposed employing OCDM technology which was appropriate for variable packets transmission and allow the label ...
Yu-bao WANG, Shao-yu ZHI
doaj   +2 more sources

Importance sampling schemes for evidence approximation in mixture models

open access: yes, 2014
The marginal likelihood is a central tool for drawing Bayesian inference about the number of components in mixture models. It is often approximated since the exact form is unavailable.
Lee, Jeong Eun, Robert, Christian P.
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Home - About - Disclaimer - Privacy