Results 81 to 90 of about 2,914,902 (352)

Efficacy and Safety of Infliximab Biosimilar (REMSIMA) in Patients With Ankylosing Spondylitis After Switching From Infliximab Reference Product: 12 Months Comparative Open-label Study [PDF]

, 2022
Abdulsatar J. Mathkhor, Amer Khudhairy, Abdulnasser Abdullah   +2 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Silicon Photonics towards Disaggregation of Resources in Data Centers

Applied Sciences, 2018
In this paper, we demonstrate two subsystems based on Silicon Photonics, towards meeting the network requirements imposed by disaggregation of resources in Data Centers.
Miltiadis Moralis-Pegios, Nikolaos Terzenidis, George Mourgias-Alexandris, Konstantinos Vyrsokinos   +3 more
doaj   +1 more source

Real-World Efficacy and Safety of Tafluprost in Primary Open-Angle Glaucoma Patients with Corneal Disorders: A Taiwan Experience

Journal of Ophthalmology, 2022
Purpose. To investigate the efficacy and safety of switching to 0.0015% tafluprost ophthalmic solution with reduced benzalkonium chloride (BAK) on primary open-angle glaucoma (POAG) patients with corneal disorders under 0.005% latanoprost treatment ...
Ju-Kuo Lin, Fu-Tsung Wei, Yi-Chun Liu, Yung-Chang Yen   +3 more
doaj   +1 more source

Emulation of GMPLS-controlled Ethernet Label Switching [PDF]

2009 5th International Conference on Testbeds and Research Infrastructures for the Development of Networks & Communities and Workshops, 2009
Last decades bridged Ethernet has been the de facto standard layer 2 technology for LAN environments. This is mainly because it is easy to deploy, it has low cost and is relatively robust. These attractive properties together with highly increasing PHY speeds result in several initiatives of research projects and standardization bodies to extend ...
Tavernier, Wouter, Papadimitriou, D., Colle, Didier, Pickavet, Mario, Demeester, Piet   +4 more
openaire   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Subcutaneous Sarilumab in Patients With Rheumatoid Arthritis who Previously Received Subcutaneous Sarilumab or Intravenous Tocilizumab: An Open‐Label Extension of a Randomized Clinical Trial

ACR Open Rheumatology, 2020
Objective This post hoc analysis evaluated the safety and efficacy of open‐label sarilumab in patients with rheumatoid arthritis (RA) who completed the phase III double‐blind ASCERTAIN study (NCT01768572) and switched from intravenous (IV) tocilizumab to
Paul Emery, Hubert vanHoogstraten, Karthinathan Thangavelu, Erin Mangan, Gregory St John, Patrick Verschueren   +5 more
doaj   +1 more source

Performance evaluation of MPLS-enabled communications infrastructure for wide area monitoring systems [PDF]

, 2015
In order to obtain the transient power system measurement information, Wide Area Monitoring Systems (WAMS) should be able to collect Phasor Measurement Unit (PMU) data in a timely manner.
Ashton, PM, Golshani, M, Pisica, I, Taylor, GA   +3 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Two‐mode multiplexed Fourier‐based labels

Electronics Letters
A two‐mode optical packet switching architecture using an optical multiport mode‐division multiplexing label generator and processor is proposed. By combining optical labels on two modes, the number of labels is increased exponentially.
Takahiro Kodama, Gabriella Cincotti
doaj   +1 more source