Results 101 to 110 of about 35,153 (355)

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

Advanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia, Yonghui Gan, Jia Li, Lilin Li, Hailan Meng, Min Sun, Lei Ye, Rui Mao, Xiang Cao, Shengnan Xia, Xinyu Bao, Renyuan Liu, Meijuan Zhang, Yun Xu   +13 more
wiley   +1 more source

Otoneurologic Evaluation in children with school difficulties: vestibular function investigation

Brazilian Journal of Otorhinolaryngology, 2007
Summary: According to the literature, child vestibular dysfunctions can considerably affect their ability of communication and school performance. Aim: to study the vestibular function in children with school difficulties and associated symptoms.
Eloisa Sartori Franco, Ivone Panhoca
doaj   +1 more source

Vestibular rehabilitation in elderly patients with dizziness [PDF]

, 2007
BACKGROND: the aging of the population is a natural process and is manifested by a decline in the functions of several organs. Vestibular rehabilitation (VR) is a therapeutic process that seeks to promote a significant reduction in the symptoms of the ...
Jurkiewicz, Ari Leon, Marques, Jair Mendes, Martins-bassetto, Jackeline, Zanardini, Francisco Halilla, Zeigelboim, Bianca Simone   +4 more
core   +2 more sources

Microglial GPR35 Ameliorates Epileptogenesis and Neuroinflammation via PDGFA Domain 2 Signaling

Advanced Science, EarlyView.
Activation of microglial G protein–coupled receptor 35 (GPR35) by L‐kynurenic acid (L‐Kyna) initiates a platelet‐derived growth factor A (PDGFA)–dependent phosphoinositide 3‐kinase–protein kinase B (PI3K–AKT) signaling cascade that dampens hippocampal neuroinflammation, thereby restraining epileptogenesis, lowering seizure susceptibility, and ...
Qi Wang, Tingting Qu, Qibing Sun, Ran Li, Junfei Dong, Yuming Du, Ziyin Xuan, Lei Wang, Hanli Li, Jianyun Sun, Fangliang Chen, Jinshuai Liu, Zifan Yang, Jianxiang Lei, Qian Yang, Bin Wang, Zhiming Zhou, Yu Wang   +17 more
wiley   +1 more source

Microglial Membranes Wrapped Ultrasmall Medium‐Entropy Ru Single‐Atom Nanozyme: Enhanced Catalysis for Accelerating Inflammation/Redox Microenvironment Regulation in Intracerebral Hemorrhage

Advanced Science, EarlyView.
PtRhIr/Ru SAN@M nanozymes cross the blood–brain barrier and selectively accumulate in hemorrhagic brain regions. By mimicking multiple enzyme activities, they attenuate oxidative stress, modulate microglial polarization toward an anti‐inflammatory phenotype, inhibit ferroptosis, and promote neuronal repair.
Jiebo Li, Penghui Wei, Yuanbo Pan, Hongjia Zheng, Jiajun Hu, Qianxi Chen, Zhongyuan Shen, Yongrui Hu, Jiajun Wu, Fuxin Lin, Fuxiang Chen, Chenyu Ding, Wenhua Fang, Yuanxiang Lin, Dezhi Kang, Yuxiang Gu, Yang Zhu, Dengliang Wang   +17 more
wiley   +1 more source

Avaliação vestibular em mulheres com disfunção temporomandibular Vestibular evaluation in women with temporomandibular dysfunction

Revista CEFAC, 2007
OBJETIVO: avaliar o comportamento vestibular em pacientes com disfunção temporomandibular. MÉTODOS: avaliaram-se 27 pacientes do sexo feminino, na faixa etária de 30 a 53 anos, encaminhadas do Centro de Diagnóstico e Tratamento da Articulação ...
Bianca Simone Zeigelboim, Ari Leon Jurkiewicz, Jackeline Martins-Bassetto, Karlin Fabianne Klagenberg   +3 more
doaj   +1 more source

Membrane Stress in the Human Labyrinth and Meniere Disease: A Model Analysis [PDF]

, 2015
Daniel J. Pender
openalex   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

Advanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan, Haicang Zhang, Liping Tong, Di Chen   +3 more
wiley   +1 more source

Acute respiratory failure as presentation of late-onset Pompe disease complicating the diagnostic process as a labyrinth: a case report [PDF]

, 2018
Francesco Menzella, Luca Codeluppi, Mirco Lusuardi, Carla Galeone, Franco Valzania, Nicola Facciolongo   +5 more
openalex   +3 more sources

Myocardial Infarction with Non-Obstructive Coronary Artery Disease: The Labyrinth of Investigations. Case Report and Review of the Literature [PDF]

, 2021
Paul Simion, Bogdan Artene, Ionut Achiței, Iulian Theodor Matei, Antoniu Octavian Petriş, Nicolae-Dan Tesloianu   +5 more
openalex   +1 more source