Results 61 to 70 of about 37,366 (242)

Expanding the Toolbox for Inducible Protein Expression With Automation‐enabled Generation of Glycomimetics

Chemistry – A European Journal, EarlyView.
Inducible protein expression is a cornerstone of many aspects of industrial and molecular biotechnological processes. 2′‐fucosyl isopropyl‐β‐D‐thiogalactopyranose (2′F‐IPTG) and 2′‐fucosyl isobutyl‐C‐galactoside (2′F‐IBCG) mimics were explored for protein expression studies.
Ashley E. DeYong, Keevan C. Marion, Murat Ozturk, Sanjeeva Kumar Murali, Fatima Enam, Thomas J. Mansell, Nicola L. B. Pohl   +6 more
wiley   +1 more source

Pensar con y a partir del operón

Revista Colombiana de Filosofía de la Ciencia
Este artículo sostiene que el operón lac propuesto por François Jacob y Jacques Monod en 1961 superó los campos de la cinética enzimática y la genética bacteriana en los que se estableció originalmente porque impulsó una metodología de análisis, el ...
Vivette García Deister, Miguel López Paleta   +1 more
doaj   +1 more source

Regulation of endothelial-specific transgene expression by the LacI repressor protein in vivo. [PDF]

PLoS ONE, 2014
Genetically modified mice have played an important part in elucidating gene function in vivo. However, conclusions from transgenic studies may be compromised by complications arising from the site of transgene integration into the genome and, in ...
Susan K Morton, Daniel J Chaston, Brett K Baillie, Caryl E Hill, Klaus I Matthaei   +4 more
doaj   +1 more source

Late Stage Mannan Metabolism in Cellvibrio japonicus Requires the Combined Action of a Mannosyl‐Glucose Phosphorylase and a Mannobiose Epimerase

Molecular Microbiology, EarlyView.
Model for the non‐PTS utilization of manno‐oligosaccharides by Cellvibrio japonicus. The Mgp130A and EpiA enzymes are essential for the utilization of mannose residues. ABSTRACT Manno‐oligosaccharides and their metabolism play important roles in gut health, pharmaceutical development, and renewable chemical production.
Jessica K. Novak, Jeffrey G. Gardner
wiley   +1 more source

Concentration and Length Dependence of DNA Looping in Transcriptional Regulation [PDF]

, 2008
In many cases, transcriptional regulation involves the binding of transcription factors at sites on the DNA that are not immediately adjacent to the promoter of interest.
Beausang, John F., Blumberg, Seth, Garcia, Hernan G., Han, Lin, Nelson, Philip C., Phillips, Rob, Towles, Kevin B.   +6 more
core   +12 more sources

LacSwitch® II Regulation of Connexin43 cDNA Expression Enables Gap-Junction Single-Channel Analysis

BioTechniques, 2003
Metabolic and electrical coupling through gap junction channels is implicated in cell differentiation, tissue homeostasis, and electrotonic propagation of signals in excitable tissues.
G. Zhong, P.L. Mantel, X. Jiang, T. Jarry-Guichard, D. Gros, C. Labarrere, A.P. Moreno   +6 more
doaj   +1 more source

Physical Constraints and Functional Characteristics of Transcription Factor-DNA Interaction [PDF]

, 2001
We study theoretical ``design principles'' for transcription factor-DNA interaction in bacteria, focusing particularly on the statistical interaction of the transcription factors (TF's) with the genomic background (i.e., the genome without the target ...
Berg, Berg, Berman, Bryngelson, Bussemaker, Davidson, deHaseth, Dr  ge, Elowitz, Fields, Frank, Gerland, Kalir, Kao-Huang, Pabo, Raumann, Record, Sarai, Sengupta, Stormo, Takeda, von Hippel, Winter, Winter, Yuh   +24 more
core   +3 more sources

The lac operon galactoside acetyltransferase

Comptes Rendus. Biologies, 2005
Of the proteins encoded by the three structural genes of the lac operon, the galactoside acetyltransferase (thiogalactoside transacetylase, LacA, GAT) encoded by lacA is the only protein whose biological role remains in doubt.
openaire   +2 more sources

Rhizobial motility preference in root colonization of Medicago truncatula

New Phytologist, EarlyView.
Summary Tunnel‐like infection thread (IT) structures support root colonization by symbiotic nitrogen‐fixing rhizobia bacteria in most legume species. These tip‐grown structures are key to directing rhizobia from root hairs to developing nodules, where they are hosted to fix nitrogen.
Anaïs Delers, Anne Bennion, Ambre Guillory, Lisa Frances, Elizaveta Krol, Fanny Bonnafous, Laurena Medioni, Javier Serrania, Rémi Peyraud, Joëlle Fournier, Fernanda de Carvalho‐Niebel, Anke Becker   +11 more
wiley   +1 more source

Stochastic dynamics of macromolecular-assembly networks [PDF]

, 2006
The formation and regulation of macromolecular complexes provides the backbone of most cellular processes, including gene regulation and signal transduction.
Arkin A, Hill TL, Jose MG Vilar, Leonor Saiz, Ptashne M   +4 more
core   +3 more sources