Results 81 to 90 of about 128,431 (240)

LacSwitch® II Regulation of Connexin43 cDNA Expression Enables Gap-Junction Single-Channel Analysis

open access: yesBioTechniques, 2003
Metabolic and electrical coupling through gap junction channels is implicated in cell differentiation, tissue homeostasis, and electrotonic propagation of signals in excitable tissues.
G. Zhong   +6 more
doaj   +1 more source

A Sucrose‐Utilisation Gene Cluster Contributes to Colonisation of Horse Chestnut by Pseudomonas syringae pv. aesculi

open access: yesMolecular Plant Pathology, Volume 26, Issue 7, July 2025.
We show that a sucrose gene cluster enhances the fitness and pathogenicity of Pseudomonas syringae pv. aesculi on horse chestnut, highlighting sucrose metabolism as important for tree colonisation. ABSTRACT Pseudomonas syringae pathovar aesculi (E‐Pae) causes bleeding canker disease in the woody tissue of European horse chestnut (HC).
Sabrine Dhaouadi   +8 more
wiley   +1 more source

EtcABC, a Putative EII Complex, Regulates Type 3 Fimbriae via CRP-cAMP Signaling in Klebsiella pneumoniae

open access: yesFrontiers in Microbiology, 2019
Biofilm formation by Klebsiella pneumoniae on indwelling medical devices increases the risk of infection. Both type 1 and type 3 fimbriae are important factors in biofilm formation by K. pneumoniae. We found that a putative enzyme II (EII) complex of the
Novaria Sari Dewi Panjaitan   +5 more
doaj   +1 more source

Construction of a RFP-lacZα bicistronic reporter system and its application in lead biosensing.

open access: yesPLoS ONE, 2020
The combination of a fluorescent reporter and enzymatic reporter provides a flexible and versatile way for the study of diverse biological processes, such as the detection of transcription and translation.
Chang-Ye Hui   +5 more
doaj   +1 more source

The essential yhcSR two-component signal transduction system directly regulates the lac and opuCABCD operons of Staphylococcus aureus. [PDF]

open access: yesPLoS ONE, 2012
Our previous studies suggested that the essential two-component signal transduction system, YhcSR, regulates the opuCABCD operon at the transcriptional level, and the Pspac-driven opuCABCD partially complements the lethal effects of yhcS antisense RNA ...
Meiying Yan   +3 more
doaj   +1 more source

Biological Consequences of Tightly Bent DNA: The Other Life of a Macromolecular Celebrity [PDF]

open access: yes, 2006
The mechanical properties of DNA play a critical role in many biological functions. For example, DNA packing in viruses involves confining the viral genome in a volume (the viral capsid) with dimensions that are comparable to the DNA persistence length ...
Garcia, Hernan G.   +8 more
core   +3 more sources

Assessment and Mitigation of CRISPR‐Cas9‐Induced Nontargeted Translocations

open access: yesAdvanced Science, Volume 12, Issue 21, June 5, 2025.
Various inverted repeat elements are dispersed throughout genomes. This study reveals that these elements can cause significant chromosomal rearrangements when CRISPR editing occurs in their proximity. The risk can be mitigated by incorporating inverted repeat‐homologous segments into the CRISPR system, which represents a promising strategy for ...
Zhiyang Hou   +6 more
wiley   +1 more source

Modelling Biological Systems: A New Algorithm for the Inference of Boolean Networks

open access: yesMathematics, 2021
Biological systems are commonly constituted by a high number of interacting agents. This great dimensionality hinders biological modelling due to the high computational cost.
Mario Rubio-Chavarría   +3 more
doaj   +1 more source

Enhanced Growth of Bone Marrow‐Derived Mesenchymal Stem Cells on the Microcarriers Tethered With Engineered Basic Fibroblast Growth Factor

open access: yesBiotechnology Journal, Volume 20, Issue 6, June 2025.
Graphical Abstract and Lay Summary Microcarrier‐based bioreactors were developed for efficient expansion of human mesenchymal stem cells (hMSCs) by tethering basic fibroblast growth factor (bFGF) to collagen‐coated microcarriers using collagen‐binding peptides (CBP).
Shiina Pasanen   +4 more
wiley   +1 more source

Transcriptional control of the H-NS antagonists LeuO and RcsB-BglJ in Escherichia coli [PDF]

open access: yes, 2012
The bacterial nucleoid-associated protein (NAP) H-NS is involved in the organization and compaction of the bacterial chromatin and acts as a global respressor, mainly of genes that have been acquired by horizontal gene transfer and that are related to ...
Stratmann, Thomas
core  

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