Results 81 to 90 of about 37,366 (242)

Interaction of Staphylococcus aureus di‐iron Repair of Iron Centers protein with the iron–sulfur cluster assembly SUF system

Protein Science, Volume 35, Issue 1, January 2026.
Abstract Repair of Iron Centers (RIC) proteins are present in several pathogens, including Staphylococcus aureus, contributing to resistance to nitroxidative stress and virulence. In this work, we investigated the molecular mechanisms by which S. aureus RIC facilitates iron mobilization, through structural analyses and functional studies.
Frederico M. Lourenço, Liliana S. O. Silva, Mafalda R. Almeida, Filipe Folgosa, Pedro M. Matias, Sandra M. Carvalho, João C. Lima, Célia V. Romão, Lígia M. Saraiva   +8 more
wiley   +1 more source

Modelling Biological Systems: A New Algorithm for the Inference of Boolean Networks

Mathematics, 2021
Biological systems are commonly constituted by a high number of interacting agents. This great dimensionality hinders biological modelling due to the high computational cost.
Mario Rubio-Chavarría, Cristina Santamaría, Belén García-Mora, Gregorio Rubio   +3 more
doaj   +1 more source

Analysis of the lactose metabolism in E. coli using sum-of-squares decomposition [PDF]

, 2005
We provide a system-theoretic analysis of the mathematical model of lactose induction in E.coli which predicts the level of lactose induction into the cell for specified values of external lactose.
Ahmadzadeh, Ali, Halasz, Adam, Jadbabaie, Ali, Kumar, Vijay, Prajna, Stephen   +4 more
core  

In Vivo Biosynthesis and Direct Incorporation of Noncanonical Amino Acids into Proteins

ChemBioChem, Volume 26, Issue 22, November 17, 2025.
This review evaluates engineered (semi)autonomous cell systems for the biosynthesis and incorporation of noncanonical amino acids (ncAAs) into proteins. While semi‐autonomous cells convert supplied precursors into ncAAs autonomous cells integrate biosynthetic pathways that produce these building blocks intracellularly.
Jan Hendrik Illies, Tim Moritz Weber, Ivana Drienovská   +2 more
wiley   +1 more source

Sequence Dependence of Transcription Factor-Mediated DNA Looping [PDF]

, 2012
DNA is subject to large deformations in a wide range of biological processes. Two key examples illustrate how such deformations influence the readout of the genetic information: the sequestering of eukaryotic genes by nucleosomes, and DNA looping in ...
Barry, Bellomy, Bellomy, Brenowitz, Butler, Chen, Chen, Cloutier, Cloutier, Drew, Du, Echols, Edelman, Finzi, Frank, Garcia, Geggier, Han, Hirsh, Hogan, Hsieh, Jacobson, Krämer, Lewis, Lowary, Luger, Luijsterburg, Martin Lindén, Matthews, Mehta, Milstein, Morgan, Müller, Newman, Normanno, Oehler, Olson, Peters, Plischke, Ptashne, Rippe, Rob Phillips, Rutkauskas, Saiz, Schafer, Schleif, Segall, Shimada, Stephanie Johnson, Swigon, Tolhuis, Towles, Vanzi, Villa, Watson, Whitson, Whitson, Widom, Wong, Xu, Yin, Zhan, Zhang   +62 more
core   +4 more sources

Genetic Surfaceome E. coli Reprogramming Enables Selective Water Oxidation

Advanced Materials, Volume 37, Issue 47, November 27, 2025.
A novel enzymatic material based on bilirubin oxidase (BOD) surface‐expressed on E. coli for effective electrocatalysis is reported. With this material, highly efficient and selective water oxidation is achieved, a critical half reaction for synthetic photosynthesis. Abstract Programming catalytic behavior at the microbial genome level is a frontier in
Graziela C. Sedenho, Jéssica C. Pacheco, Melanie Gut, Filipe C. D. A. Lima, Sunanda Dey, Frank N. Crespilho, Ariel L. Furst   +6 more
wiley   +1 more source

Interplay of gene expression noise and ultrasensitive dynamics affects bacterial operon organization.

PLoS Computational Biology, 2012
Bacterial chromosomes are organized into polycistronic cotranscribed operons, but the evolutionary pressures maintaining them are unclear. We hypothesized that operons alter gene expression noise characteristics, resulting in selection for or against ...
J Christian J Ray, Oleg A Igoshin
doaj   +1 more source

Structure and function of negative feedback loops at the interface of genetic and metabolic networks [PDF]

, 2006
The molecular network in an organism consists of transcription/translation regulation, protein-protein interactions/modifications and a metabolic network, together forming a system that allows the cell to respond sensibly to the multiple signal molecules
Andersson, Anna M. C., Krishna, Sandeep, Semsey, Szabolcs, Sneppen, Kim   +3 more
core   +4 more sources

RNA polymerase structure and function at lac operon

Comptes Rendus. Biologies, 2005
Transcription of E. coli lac operon by RNA polymerase (RNAP) is a classic example of how the basic functions of this enzyme, specifically the ability to recognize/bind promoters, melt the DNA and initiate RNA synthesis, is positively regulated by transcription activators, such as cyclic AMP ...
Sergei, Borukhov, Jookyung, Lee
openaire   +2 more sources

Origin and characterization of cyclodepsipeptides: Comprehensive structural approaches with focus on mass spectrometry analysis of alkali‐cationized molecular species

Mass Spectrometry Reviews, Volume 44, Issue 6, Page 1013-1098, November/December 2025.
Abstract Cyclodepsipeptides (CDPs) represent a huge family of chemically and structurally diverse molecules with a wide ability for molecular interactions. CDPs are cyclic peptide‐related natural products made up of both proteinogenic and nonproteinogenic amino acids linked by amide and ester bonds.
Sophie Liuu, Annelaure Damont, Alain Perret, Olivier Firmesse, François Becher, Gwenaëlle Lavison‐Bompard, Amandine Hueber, Amina S. Woods, Ekaterina Darii, François Fenaille, Jean‐Claude Tabet   +10 more
wiley   +1 more source