Results 81 to 90 of about 128,431 (240)
LacSwitch® II Regulation of Connexin43 cDNA Expression Enables Gap-Junction Single-Channel Analysis
Metabolic and electrical coupling through gap junction channels is implicated in cell differentiation, tissue homeostasis, and electrotonic propagation of signals in excitable tissues.
G. Zhong+6 more
doaj +1 more source
We show that a sucrose gene cluster enhances the fitness and pathogenicity of Pseudomonas syringae pv. aesculi on horse chestnut, highlighting sucrose metabolism as important for tree colonisation. ABSTRACT Pseudomonas syringae pathovar aesculi (E‐Pae) causes bleeding canker disease in the woody tissue of European horse chestnut (HC).
Sabrine Dhaouadi+8 more
wiley +1 more source
Biofilm formation by Klebsiella pneumoniae on indwelling medical devices increases the risk of infection. Both type 1 and type 3 fimbriae are important factors in biofilm formation by K. pneumoniae. We found that a putative enzyme II (EII) complex of the
Novaria Sari Dewi Panjaitan+5 more
doaj +1 more source
Construction of a RFP-lacZα bicistronic reporter system and its application in lead biosensing.
The combination of a fluorescent reporter and enzymatic reporter provides a flexible and versatile way for the study of diverse biological processes, such as the detection of transcription and translation.
Chang-Ye Hui+5 more
doaj +1 more source
The essential yhcSR two-component signal transduction system directly regulates the lac and opuCABCD operons of Staphylococcus aureus. [PDF]
Our previous studies suggested that the essential two-component signal transduction system, YhcSR, regulates the opuCABCD operon at the transcriptional level, and the Pspac-driven opuCABCD partially complements the lethal effects of yhcS antisense RNA ...
Meiying Yan+3 more
doaj +1 more source
Biological Consequences of Tightly Bent DNA: The Other Life of a Macromolecular Celebrity [PDF]
The mechanical properties of DNA play a critical role in many biological functions. For example, DNA packing in viruses involves confining the viral genome in a volume (the viral capsid) with dimensions that are comparable to the DNA persistence length ...
Garcia, Hernan G.+8 more
core +3 more sources
Assessment and Mitigation of CRISPR‐Cas9‐Induced Nontargeted Translocations
Various inverted repeat elements are dispersed throughout genomes. This study reveals that these elements can cause significant chromosomal rearrangements when CRISPR editing occurs in their proximity. The risk can be mitigated by incorporating inverted repeat‐homologous segments into the CRISPR system, which represents a promising strategy for ...
Zhiyang Hou+6 more
wiley +1 more source
Modelling Biological Systems: A New Algorithm for the Inference of Boolean Networks
Biological systems are commonly constituted by a high number of interacting agents. This great dimensionality hinders biological modelling due to the high computational cost.
Mario Rubio-Chavarría+3 more
doaj +1 more source
Graphical Abstract and Lay Summary Microcarrier‐based bioreactors were developed for efficient expansion of human mesenchymal stem cells (hMSCs) by tethering basic fibroblast growth factor (bFGF) to collagen‐coated microcarriers using collagen‐binding peptides (CBP).
Shiina Pasanen+4 more
wiley +1 more source
Transcriptional control of the H-NS antagonists LeuO and RcsB-BglJ in Escherichia coli [PDF]
The bacterial nucleoid-associated protein (NAP) H-NS is involved in the organization and compaction of the bacterial chromatin and acts as a global respressor, mainly of genes that have been acquired by horizontal gene transfer and that are related to ...
Stratmann, Thomas
core