Results 81 to 90 of about 113,489 (230)

The essential yhcSR two-component signal transduction system directly regulates the lac and opuCABCD operons of Staphylococcus aureus. [PDF]

open access: yesPLoS ONE, 2012
Our previous studies suggested that the essential two-component signal transduction system, YhcSR, regulates the opuCABCD operon at the transcriptional level, and the Pspac-driven opuCABCD partially complements the lethal effects of yhcS antisense RNA ...
Meiying Yan   +3 more
doaj   +1 more source

Transient repression of the lac operon — the effect of a lac promoter deletion [PDF]

open access: yesFEBS Letters, 1970
Experiments have been done to show whether the lac promoter delection L1, which partly alleviates catabolite repression, also affects transient repression of lac. In stain L1/F′M15 all of the β‐galactosidase is synthesized from a chromosomal gene cis to L1, whereas 98% of the thiogalactosidase transacetylase is synthesized from an episomal gene cis to ...
openaire   +3 more sources

Growth strategy of microbes on mixed carbon sources [PDF]

open access: yesNature Communications, 10(1), p.1279, 2017
A classic problem in microbiology is that bacteria display two types of growth behavior when cultured on a mixture of two carbon sources: the two sources are sequentially consumed one after another (diauxie) or they are simultaneously consumed (co-utilization).
arxiv   +1 more source

Engineering Chromosome Bridges Through CRISPR/Cas9 to Decipher the Impact of Intercentromeric Distance on Resolution Dynamics

open access: yesThe FASEB Journal, Volume 39, Issue 9, 15 May 2025.
Chromosome bridge resolution during mitosis is influenced by the length of the bridging chromatin. Using CRISPR/Cas9, we engineered chromosome bridges with precisely defined intercentromeric distances. Results on the progression of these bridges during mitosis revealed that longer bridges require greater kinetochore separation to break than shorter ...
Teresa Anglada   +3 more
wiley   +1 more source

Modelling Biological Systems: A New Algorithm for the Inference of Boolean Networks

open access: yesMathematics, 2021
Biological systems are commonly constituted by a high number of interacting agents. This great dimensionality hinders biological modelling due to the high computational cost.
Mario Rubio-Chavarría   +3 more
doaj   +1 more source

Geometric characterization of data sets with unique reduced Gröbner bases [PDF]

open access: yesBulletin of Mathematical Biology 81 (2019) 2691-2705, 2018
Model selection based on experimental data is an important challenge in biological data science. Particularly when collecting data is expensive or time consuming, as it is often the case with clinical trial and biomolecular experiments, the problem of selecting information-rich data becomes crucial for creating relevant models.
arxiv   +1 more source

Polycistronic Effects of Catabolite Repression on the lac Operon [PDF]

open access: yesJournal of Bacteriology, 1972
The catabolite repression caused by glucose and glucose-6-phosphate has been studied for both β-galactosidase and thiogalactoside transacetylase, the products of the operator proximal and distal cistrons of the lac operon, respectively. We find that both cistrons are affected coordinately by this form of repression.
Allen E. Silverstone, Boris Magasanik
openaire   +3 more sources

Overlooked and misunderstood: A morpho‐molecular revision of Ditrichaceae s.str. (Dicranidae, Bryophyta), with a focus on the Holarctic species of Ditrichum

open access: yesTAXON, Volume 74, Issue 2, Page 223-259, April 2025.
Abstract We revised the Holarctic taxa of Ditrichaceae on the basis of both organellar DNA sequence data and morphological traits. After the removal of phylogenetically discordant elements related to Flexitrichum and Rhamphidium, the remaining representatives of the family cluster into three well‐supported lineages, which are recognized here as the ...
Vladimir Fedosov   +4 more
wiley   +1 more source

A Single‐Plasmid Inducible‐Replication System for High‐Yield Production of Short Ff (f1, M13 or fd)‐Phage‐Derived Nanorods

open access: yesMicrobial Biotechnology, Volume 18, Issue 4, April 2025.
Single‐plasmid inducible‐replication system for biological nanorod production was developed based on the knowledge of replication and biology of the Ff (f1, fd or M13) bacteriophages from which they are derived. Design described here overcomes the replication bottlenecks, adjusts the production of the major coat protein and simplifies the preproduction
Rayén Ignacia León‐Quezada   +5 more
wiley   +1 more source

Interplay of gene expression noise and ultrasensitive dynamics affects bacterial operon organization.

open access: yesPLoS Computational Biology, 2012
Bacterial chromosomes are organized into polycistronic cotranscribed operons, but the evolutionary pressures maintaining them are unclear. We hypothesized that operons alter gene expression noise characteristics, resulting in selection for or against ...
J Christian J Ray, Oleg A Igoshin
doaj   +1 more source

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