Results 91 to 100 of about 74,505 (292)

lactams

, 2014
Citation: 'lactams' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.L03435 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial usage
openaire   +1 more source

Organocatalytic Enantioselective Michael/Cyclization Domino Reaction between 3‑Amideoxindoles and α,β-Unsaturated Aldehydes: One-Pot Preparation of Chiral Spirocyclic Oxindole-γ-lactams

, 2017
The first organocatalytic enantioselective Michael/cyclization domino reaction between 3-amideoxindoles and α,β-unsaturated aldehydes is described. After sequential oxidation with pyridinium chlorochromate, a direct and one-pot preparation of highly ...
Li-Xin Wang (1444531), Zheng-Bing Zhang (3846637), Feng Chen (25347), Xiao Wang (19312), Lin Peng (455883), Peng Yang (296696), Chao Chen (195669)   +6 more
core   +1 more source

β-Lactam Allergy and Cross-Reactivity: A Clinician’s Guide to Selecting an Alternative Antibiotic

Journal of Asthma and Allergy, 2021
Cristiano Caruso,1 Rocco Luigi Valluzzi,2 Stefania Colantuono,1 Francesco Gaeta,1 Antonino Romano3,4 1Allergy Unit, Columbus Hospital, Fondazione Policlinico A.
Caruso C, Valluzzi RL, Colantuono S, Gaeta F, Romano A   +4 more
doaj  

Insights into the anticancer activity of chiral alkylidene-β-lactams and alkylidene-γ-lactams: Synthesis and biological investigation

, 2022
Chiral alkylidene-β-lactams and alkylidene-γ-lactams were synthesized and screened for their in vitro activity against four human cancer cell lines (melanoma, esophageal, lung and fibrosarcoma carcinoma).
Ribeiro, Ana Bela Sarmento, Laranjo, Mafalda, Gonçalves, Ana Cristina, Botelho, M. Filomena, Alves, Nuno G., Alves, Américo J. S., Gomes, Clara S. B., Pinho e Melo, Teresa M. V. D.   +7 more
core   +1 more source

Initial antibiotic selection and microbiological recurrence in treated bacteriuria caused by low-risk AmpC-harboring Enterobacterales: serratia marcescens, Morganella morganii, and Providencia spp.

Antimicrobial Stewardship & Healthcare Epidemiology
Objective: Despite updated guidance supporting antimicrobial susceptibility testing-guided antibiotic selection for low-risk AmpC-harboring organisms (Serratia marcescens, Morganella morganii, and Providencia spp.), broad-spectrum AmpC-stable β-lactams ...
Yingsi Fang, Matthew Gwiazdon, Ryan Chapin, Christopher McCoy, Kendall Bell   +4 more
doaj   +1 more source

Diastereoselectivity in Mn(III)-Promoted 4-exo-trig Cyclization of Enamides to β-Lactams

, 2016
The effect of chiral substituents on the enamide nitrogen atom upon the diastereoselection of the Mn(III)-mediated 4-exo-trig cyclization to β-lactams was studied.
Andrea DAnnibale (3076185), Floriana Umani (3076188), Corrado Trogolo (3076191), Daniele Nanni (1731088)   +3 more
core   +1 more source

The Development of the First Catalyzed Reaction of Ketenes and Imines:  Catalytic, Asymmetric Synthesis of β-Lactams

, 2016
We report practical methodology for the catalytic, asymmetric synthesis of β-lactams resulting from the development of a catalyzed reaction of ketenes (or their derived zwitterionic enolates) and imines.
Ahmed M. Hafez (2714233), Dana Ferraris (1523554), Brandon Young (470884), Harald Wack (2694217), Andrew E. Taggi (2520316), Thomas Lectka (1357518)   +5 more
core   +1 more source

Synthesis of Novel Chiral Spiroisoxazolidine‐β‐Lactams from 6‐Alkylidenepenicillanates: A 1,3‐Dipolar Cycloaddition Approach

, 2020
The synthesis of a library of 6‐alkylidene‐β‐lactams, derived from 6‐aminopenicillanic acid is reported. The 1,3‐dipolar cycloaddition of these 6‐alkylidenepenicillanates with nitrones was explored as an approach to synthesize novel chiral ...
Teresa M. V. D. Pinho e Melo, Melo, Teresa M. V. D. Pinho e, Américo J. S. Alves, Alves, Américo J. S.   +3 more
core   +1 more source

Network meta-analysis of success rate and safety in antibiotic treatments of bronchitis

International Journal of COPD, 2017
Jinghua Wang,1 Haiyang Xu,2 Pan Liu,3 Mingxian Li4 1Pediatric of Rheumatology, Immunology and Allergy, The First Hospital of Jilin University, Changchun, 2Department of Anesthesiology, The First Hospital of Jilin University, Changchun, 3Department of ...
Wang J, Xu H, Liu P, Li M
doaj  

Photoredox-Catalyzed Tandem Radical Cyclization/Hydroxylation for the Synthesis of 4‑Hydroxyalkyl-3,3-difluoro-γ-lactams

The photoredox-catalyzed radical difluoroalkylation/cyclization/hydroxylation cascade reaction of various 2-bromo-2,2-difluoro-N-arylacetamides containing unactivated alkene moieties has been developed, providing green and efficient access to various 4 ...
Can Jin (685561), Bin Sun (210373), Jieli Yin (12493425), Haiyun Zhao (3569897), Kesheng Zhang (13882708), Xiaohui Zhuang (827046)   +5 more
core   +1 more source