Results 21 to 30 of about 16,821 (255)
Population designations in biomedical research: Limitations and perspectives
HLA, Volume 101, Issue 1, Page 3-15, January 2023., 2023 In biomedical research, population differences are of central interest. Variations in the frequency and severity of diseases and in treatment effects among human subpopulation groups are common in many medical conditions. Unfortunately, the practices in terms of subpopulation labeling do not exhibit the level of rigor one would expect in biomedical ...
Caroline Gombault +9 more
wiley +1 more source
JGH Open, 2021 Background and Aim The absence of lactase in the intestinal villi due to mucosal injury or genetic factors causes undigested lactose to reach the colon where it is fermented.
Rajiv Baijal, Rakesh K Tandon
doaj +1 more source
A worldwide correlation of lactase persistence phenotype and genotypes
BMC Evolutionary Biology, 2010 Background The ability of adult humans to digest the milk sugar lactose - lactase persistence - is a dominant Mendelian trait that has been a subject of extensive genetic, medical and evolutionary research.
Ingram Catherine JE +4 more
doaj +1 more source
New insights into the molecular basis of lactase non-persistence/persistence: a brief review.
Drug Discoveries & Therapeutics, 2020 Lactose, a disaccharide and main carbohydrate in milk, requires hydrolysis in the intestinal tract to release its monosaccharides galactose and glucose for use as energy source by enterocytes.
Raja A. H. Kuchay
semanticscholar +1 more source
Frontiers in Physiology, 2021 The emergence of the capacity to digest milk in some populations represents a landmark in human evolution, linking genetic change with a component of niche construction, namely dairying.
Jonathan C. K. Wells +3 more
doaj +1 more source
Medical Science Monitor, 2020 Background Debaryomyces hansenii exhibits a therapeutic effect on antibiotic-associated diarrhea (AAD) by promoting the growth of beneficial intestinal bacteria.
Yi Wu +4 more
semanticscholar +1 more source
American Journal of Clinical Nutrition, 2019 Globally, ∼70% of adults are deficient in intestinal lactase, the enzyme required for the digestion of lactose. In these individuals, the consumption of lactose-containing milk and dairy products can lead to the development of various gastrointestinal ...
R. Forsgård
semanticscholar +1 more source
Characterization of putative mannoprotein in Kluyveromyces lactis for lactase production
Synthetic and Systems Biotechnology, 2023 Lactase is a member of the β-galactosidase family of enzymes that can hydrolyze lactose into galactose and glucose. However, extracellular lactase production was still restricted to the process of cell lysis.
Xiuru Shen +5 more
doaj
Lactase persistence genotypes and malaria susceptibility in Fulani of Mali
Malaria Journal, 2011 Background Fulani are a widely spread African ethnic group characterized by lower susceptibility to Plasmodium falciparum, clinical malaria morbidity and higher rate of lactase persistence compared to sympatric tribes.
Dolo Amagana +8 more
doaj +1 more source
Lactase deficiency: latest diagnostic methods and treatment
Медицинский совет, 2013 The article tells about latest data on etiology, pathegenesis, diagnosis and treatment of lactase deficiency in children. Feces analysis for carbohydrates for diagnosis of lactase deficiency is not recommended.
M. L. Babayan
doaj +1 more source