Results 41 to 50 of about 20,877 (243)

Lactose digestion in humans: intestinal lactase appears to be constitutive whereas the colonic microbiome is adaptable

open access: yesAmerican Journal of Clinical Nutrition, 2019
Globally, ∼70% of adults are deficient in intestinal lactase, the enzyme required for the digestion of lactose. In these individuals, the consumption of lactose-containing milk and dairy products can lead to the development of various gastrointestinal ...
R. Forsgård
semanticscholar   +1 more source

Human Genetics: Lactase Persistence in a Battlefield [PDF]

open access: yes, 2020
Lactase persistence is a common genetic trait in Europeans and other pastoralists. New ancient DNA evidence from a Bronze Age battlefield indicates that selection for lactase persistence was strong and on-going in the last 3,000 ...
Saag, L
core   +1 more source

The role of a combined probiotic in the treatment of lactase deficiency

open access: yesТерапевтический архив, 2021
Aim. To study the effectiveness of the combined probiotic Bifiform and the enzyme lactase in the treatment of secondary lactase deficiency (SLD). Materials and methods.
Irina N. Ruchkina, Nina A. Fadeeva
doaj   +1 more source

The Differentiated Approach to the Treatment of Lactase Deficiency and Allergies to Cow's Milk Protein in Infants

open access: yesДетские инфекции (Москва), 2016
One of the most common pathologies in infants is a lactase deficiency and allergy to cow's milk protein. Treatment of lactase deficiency and allergies to cow's milk protein in young children requires a differentiated approach. The best food for the child'
T. A. Filatova   +3 more
doaj   +1 more source

Convergent adaptation of human lactase persistence in Africa and Europe

open access: yesNature Genetics, 2006
A SNP in the gene encoding lactase (LCT) (C/T-13910) is associated with the ability to digest milk as adults (lactase persistence) in Europeans, but the genetic basis of lactase persistence in Africans was previously unknown.
S. Tishkoff   +18 more
semanticscholar   +1 more source

New insights into the molecular basis of lactase non-persistence/persistence: a brief review.

open access: yesDrug Discoveries & Therapeutics, 2020
Lactose, a disaccharide and main carbohydrate in milk, requires hydrolysis in the intestinal tract to release its monosaccharides galactose and glucose for use as energy source by enterocytes.
Raja A. H. Kuchay
semanticscholar   +1 more source

Lactase deficiency in children and the choice of therapeutic nutrition

open access: yesЛечащий Врач
Background. Lactose is the main carbohydrate in breast milk, dairy products and is important for human physiology. Lactase deficiency is a term that is used to describe pathological conditions caused by a decrease in lactase levels (hypolactasia) or a ...
A. F. Kiosov, A. Yu. Pischalnikov
doaj   +1 more source

Variant of the lactase LCT gene explains association between milk intake and incident type 2 diabetes

open access: yesNature Metabolism
Higher milk intake is associated with lower type 2 diabetes risk in lactase non-persistent individuals, partly through gut microbiome and blood metabolites. Cow’s milk is frequently included in the human diet, but the relationship between milk intake and
K. Luo   +19 more
semanticscholar   +1 more source

Frequency of adult type-associated lactase persistence LCT-13910C/T genotypes in the Czech/Slav and Czech Roma/Gypsy populations

open access: yesGenetics and Molecular Biology, 2017
Lactase non-persistence (leading to primary lactose intolerance) is a genetically dependent inability to digest lactose in adulthood. As part of the human adaptation to dairying, the human lactase LCT-13910C/T mutation (which propagates adult expression ...
Jaroslav A. Hubácek   +5 more
doaj   +1 more source

Chemical and sensory changes during shelf-life of UHT hydrolyzed-lactose milk produced by "in batch" system employing different commercial lactase preparations.

open access: yesFood Research International, 2020
Manufacturing shelf-stable Ultra-high temperature hydrolyzed-lactose milk (UHLM) is a challenge for dairy producers, as the product undergoes chemical changes during storage due to both reducing sugars reactivity and proteolysis arising from the impurity
Riccardo Bottiroli   +5 more
semanticscholar   +1 more source

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