Results 71 to 80 of about 23,482 (213)

Effects of exogenous lactase administration on hydrogen breath excretion and intestinal symptoms in patients presenting lactose malabsorption and intolerance [PDF]

open access: yes, 2014
To establish whether supplementation with a standard oral dose of Beta-Galactosidase affects hydrogen breath excretion in patients presenting with lactose malabsorption.
Boi, MF, Gilli, A, Ibba, I, Usai, P
core   +2 more sources

Upcycling orange by‐product: phenolic bioaccessibility and technological features of jelly candies enriched with hydroalcoholic and enzymatic extracts

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 6, Page 3773-3785, April 2026.
Abstract BACKGROUND Phenolic extracts are recognized for their health‐promoting properties, although some physicochemical characteristics limit their food applications. The present study aimed to valorize orange juice by‐products through enzymatic and hydroalcoholic extraction to obtain flavonoid ingredients and to evaluate their application in pectin ...
Bárbara Morandi Lepaus   +7 more
wiley   +1 more source

The Effects of Exogenous Lactase on Improving Gastrointestinal Symp-toms in Patients with Lactose Intolerance

open access: yesمجله دانشکده پزشکی اصفهان, 2011
Background: Lactose intolerance is common in Asian population. Enzyme replacement therapy facilitates consumption of milk and dairy products for patients with lactose intolerance. Clinical evidence in our clinics indicates a nonhomogeneity in improvement
Ramin Ghahremani, Behzad Asanjarani
doaj  

Lactase persistence and milk consumption in Europe: an interdisciplinary approach involving genetics and archaeology

open access: yesDocumenta Praehistorica, 2013
The ability to digest milk during adulthood (lactase persistence) is a genetically determined trait present only in humans. Its origin and diffusion are correlated with the development of pastoralism and the consumption of fresh milk.
Michela Leonardi
doaj   +1 more source

Use of the KlADH4 promoter for ethanol-dependent production of recombinant human serum albumine in Kluyveromyces lactis [PDF]

open access: yes, 1999
KlADH4 is a gene of Kluyveromyces lactis encoding a mitochondrial alcohol dehydrogenase activity which is specifically induced by ethanol. The promoter of this gene was used for the expression of heterologous proteins in K.
CRISA A.   +6 more
core  

Homo sapiens, industrialisation and the environmental mismatch hypothesis

open access: yesBiological Reviews, Volume 101, Issue 2, Page 580-601, April 2026.
ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley   +1 more source

Pembrolizumab for Early‐Stage Triple‐Negative Breast Cancer: KEYNOTE‐522 Japan Subgroup Analysis

open access: yesCancer Science, Volume 117, Issue 4, Page 1106-1116, April 2026.
In the global, phase 3 KEYNOTE‐522 study of high‐risk early‐stage triple‐negative breast cancer (TNBC), neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab improved efficacy outcomes versus neoadjuvant chemotherapy alone. In this analysis of Japanese participants from KEYNOTE‐522, neoadjuvant pembrolizumab plus chemotherapy ...
Masato Takahashi   +16 more
wiley   +1 more source

LACTASE DEFICIENCY IN CHILDREN

open access: yesПедиатрическая фармакология, 2011
The topic of the article is the lactase deficiency in children. The most frequent clinical manifestations — diarrhea and flatulence —are not specific to this pathology. Symptoms, typical for the majority of the diseases nosologies of the digestive system,
V.A. Shcherbak, N.M. Shcherbak
doaj   +2 more sources

Polymorphism in the oxytocin promoter region in patients with lactase non-persistence is not related to symptoms

open access: yesBMC Gastroenterology, 2009
Background Oxytocin and the oxytocin receptor have been demonstrated in the gastrointestinal (GI) tract and have been shown to exert physiological effects on gut motility. The role for oxytocin in the pathophysiology of GI complaints is unknown.
Simrén Magnus   +3 more
doaj   +1 more source

Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review

open access: yesInternational Journal of Dermatology, Volume 65, Issue 4, Page 706-723, April 2026.
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska   +8 more
wiley   +1 more source

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