Results 71 to 80 of about 20,877 (243)

Refining Genetic Instruments for Dietary Intake Mendelian Randomization Using Phenome‐Wide Association Studies

Genetic Epidemiology, Volume 50, Issue 8, December 2026.
ABSTRACT Most Mendelian randomization (MR) of dietary intake use the full set of genome‐wide significant (GWS) variants in the instrumental variable (IV), likely biasing causal estimates due to pleiotropy. To characterize the common methods to handle pleiotropy in dietary intake MR, we conducted a scoping review of the literature on dietary intake MR ...
Kristen J. Sutton, Julie E. Gervis, Moomal Jatoi, Liang‐Dar Hwang, Audrey E. Hendricks, Debashis Ghosh, Kenneth E. Westerman, Joanne B. Cole   +7 more
wiley   +1 more source

Very low frequency of the lactase persistence allele LCT-13910T in the Armenian population

Annals of Human Biology, 2022
Primary lactose malabsorption is characterised by a down-regulation of lactase activity after weaning and inability to digest lactose in adulthood. It has been suggested that the historical introduction of dairying led to a positive selection for lactase
Stefan Németh, Gernot Kriegshäuser, Kristine Hovhannesyan, Hasmik Hayrapetyan, Christian Oberkanins, Tamara Sarkisian   +5 more
doaj   +1 more source

Comparative Pharmacokinetics and Safety of Orally Disintegrating and Conventional Tablet Formulations of Zastaprazan in Healthy Subjects

Pharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Zastaprazan, a potassium‐competitive acid blocker, has been developed as an orally disintegrating tablet (ODT) to improve administration flexibility. This study evaluated the pharmacokinetics and safety of a single 20 mg dose of Zastaprazan ODT administered with or without water compared with the conventional tablet in healthy volunteers.
Hyung‐Gun Kim, Seunghyun Kang, Sunyoung Min, Heejoo Hong, Moonjung Bae   +4 more
wiley   +1 more source

Lactose intolerance and gastrointestinal cow’s milk allergy in infants and children – common misconceptions revisited

World Allergy Organization Journal, 2017
Lactose is the main carbohydrate in human and mammalian milk. Lactose requires enzymatic hydrolysis by lactase into D-glucose and D-galactose before it can be absorbed.
Ralf G. Heine, Fawaz AlRefaee, Prashant Bachina, Julie C. De Leon, Lanlan Geng, Sitang Gong, José Armando Madrazo, Jarungchit Ngamphaiboon, Christina Ong, Jossie M. Rogacion   +9 more
doaj   +3 more sources

The Use of Purple Eggplant Fruit Calyx Stem (Solanum melongena L.) as an Alternative Source of Lactase-Producing Lactic Acid Bacteria

Biotropika: Journal of Tropical Biology
Lactose intolerance is a condition where the body cannot digest lactose due to a deficiency of the lactase enzyme in the digestive system, leading to various health issues and indirectly increasing the risk of stunting.
Mike Permata Sari, Afifa Radhina, Narita Indriani   +2 more
doaj   +1 more source

DIGESTIVE DISORDERS IN PREMATURELY BORN CHILDREN

Вопросы современной педиатрии, 2012
The article contains data on functional digestive disorders in newborns, mainly on the problem of lactase (disaccharidase) insufficiency. The information on the prevalence of this condition, modern classification of hypolactasia, diagnostic techniques ...
I. A. Belyaeva, E. P. Bombardirova, E. O. Tarzyan   +2 more
doaj   +1 more source

The cow’s milk allergy that wasn’t: allergy to supplemental oral lactase enzyme

Allergy, Asthma & Clinical Immunology, 2023
Background Allergy to supplemental lactase is sparsely reported in the literature with only one prior case of anaphylaxis documented [2]. Reactions to this agent can occur following cow’s milk ingestion which could lead to an erroneous diagnosis of cow’s
Sarah K. Lohrenz, A. Kanani
doaj   +1 more source

World-wide distributions of lactase persistence alleles and the complex effects of recombination and selection

Human Genetics, 2017
The genetic trait of lactase persistence (LP) is associated with at least five independent functional single nucleotide variants in a regulatory region about 14 kb upstream of the lactase gene [−13910*T (rs4988235), −13907*G (rs41525747), −13915*G ...
A. Liebert, Saioa López, B. L. Jones, N. Montalva, P. Gerbault, Winston Lau, Mark George Thomas, N. Bradman, N. Maniatis, D. Swallow   +9 more
semanticscholar   +1 more source

Sources, Transmission, and Control of Salmonella in Vertically Integrated Broiler Chicken Production: Farm, Hatchery, and Processing Plant

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT Salmonella remains one of the most important foodborne pathogens associated with poultry products, despite substantial progress in processing hygiene and antimicrobial interventions. This review critically examines the sources, transmission routes, and control strategies for Salmonella in vertically integrated broiler production systems ...
Deepak Subedi, Bharath Mallavarapu, Pranita Patil, Abhisek Niraula, Milan Kandel, Sanjay Kumar, Amit Kumar Singh   +6 more
wiley   +1 more source

Production of low-dosage lactose milk using lactase immobilised in hydrogel

International Dairy Journal, 2019
A hydrogel based on chitosan was employed for the immobilisation of lactase with the aim of hydrolysing lactose and producing low-dosage lactose milk. The degree of swelling of the hydrogel was affected by the type of aqueous solution, pH and temperature.
M. Wolf, L. Belfiore, E. Tambourgi, A. T. Paulino   +3 more
semanticscholar   +1 more source