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Topical Questions of Diagnostic and Correction of Lactase Deficiency in Children and Adolescents
The article considers a clinical manifestation of lactase deficiency in children and adolescents and its treatment. It has been proven a high therapeutic effectiveness of enzyme replacement therapy of primary and secondary lactose deficiency in breast ...
Yu.I. Reshetilov +5 more
doaj +1 more source
Our understanding of the recolonization of northwest Europe in the period leading up to the Lateglacial Interstadial relies heavily on discoveries from Gough's Cave (Somerset, UK). Gough's Cave is the richest Late Upper Palaeolithic site in the British Isles, yielding an exceptional array of human remains, stone and organic artefacts, and butchered ...
Silvia M. Bello +2 more
wiley +1 more source
Several different lactase persistence associated alleles and high diversity of the lactase gene in the admixed Brazilian population. [PDF]
Adult-type hypolactasia is a common phenotype caused by the lactase enzyme deficiency. The -13910 C>T polymorphism, located 14 Kb upstream of the lactase gene (LCT) in the MCM6 gene was associated with lactase persistence (LP) in Europeans.
Deise C Friedrich +3 more
doaj +1 more source
[Small intestinal bacterial overgrowth as a cause of lactase deficiency].
N. Fadeeva +3 more
semanticscholar +2 more sources
Homo sapiens, industrialisation and the environmental mismatch hypothesis
ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley +1 more source
Pembrolizumab for Early‐Stage Triple‐Negative Breast Cancer: KEYNOTE‐522 Japan Subgroup Analysis
In the global, phase 3 KEYNOTE‐522 study of high‐risk early‐stage triple‐negative breast cancer (TNBC), neoadjuvant pembrolizumab plus chemotherapy followed by adjuvant pembrolizumab improved efficacy outcomes versus neoadjuvant chemotherapy alone. In this analysis of Japanese participants from KEYNOTE‐522, neoadjuvant pembrolizumab plus chemotherapy ...
Masato Takahashi +16 more
wiley +1 more source
Lactose intolerance in allergic enterocolitis in infants
Background. Food allergy in the infancy is manifested clinically in damage to the skin and gastrointestinal tract. Allergic inflammation of the intestinal mucosa is accompanied by damage to the structure of enterocytes, which can lead to a significant ...
O.G. Shadrin, H.A. Haiduchyk
doaj +1 more source
Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska +8 more
wiley +1 more source
Allergy to cow's milk proteins and lactase deficiency: a clinical dilemma in infants
Background. When allergic to cow's milk proteins and lactase deficiency, the clinical symptoms of the gastrointestinal tract often have great similarities, so neonatologists and pediatricians often have serious difficulties in making a diagnosis. Surveys
A. F. Kiosov
doaj +1 more source
Clinical gastrointestinal manifestations of cow’s milk protein allergy and lactase deficiency such as diarrhea, bloating, colic, and regurgitation are quite similar, which often lead to errors in diagnoses and methods of nutritional correction. Diagnoses
S.L. Nyankovskyy +3 more
doaj +1 more source

