Results 101 to 110 of about 326,261 (230)

Evolutionary GEM: Evolution of Lactase Persistence

Western Undergraduate Research Journal: Health and Natural Sciences, 2017
Though humans are known to lose lactase ability post-weaning, some people maintain lactase production into adulthood, a condition known as lactase persistence. Global distribution patterns of lactase persistency are inconsistent; the condition is much more prevalent in some populations than others.
Patricia M. Gray, Xinghan Du
openaire   +3 more sources

Lack of Association between LCT_rs140433552*CA>del Indel Polymorphism and Lactose Intolerance in a Southern Brazilian Population

Lifestyle Genomics, 2020
Background/Aims: Polymorphisms in the enhancer of the lactase gene (LCT) are strongly associated with lactase persistence, but not always predictive of the phenotype.
Luana Caroline Oliveira, Andrey Lucas Dias Barros, Angelica Beate Winter Boldt, Gabriel Adelman Cipolla   +3 more
doaj   +1 more source

Late Pleistocene human genome suggests a local origin for the first farmers of central Anatolia [PDF]

, 2019
Anatolia was home to some of the earliest farming communities. It has been long debated whether a migration of farming groups introduced agriculture to central Anatolia.
Baird, Douglas, Benz, Marion, Feldman, Michal, Fernández-Domínguez, Eva, Goring-Morris, Nigel, Gresky, Julia [u.v.m.], Hershkovitz, Israel, May, Hila, Pearson, Jessica, Reynolds, Luke   +9 more
core   +1 more source

Assessing the Antibiotic Resistance in Food Lactic Acid Bacteria: Risks in the Era of Widespread Probiotic Use

Food Science &Nutrition, Volume 13, Issue 8, August 2025.
Targeting the potential sources and risk factors for antibiotic resistance transmittance and development of antibiotic resistant‐free probiotics. ABSTRACT Antibiotic resistance (AR) in lactic acid bacteria (LAB) has become an emerging concern in the probiotic and food industries. LAB, a key component of the human microbiota and widely used in probiotic
Salma Sherif Refaat, Zeynep Akinan Erdem, Muhammed Zahid Kasapoğlu, Fatih Ortakcı, Enes Dertli   +4 more
wiley   +1 more source

Genetic and cultural adaptations underlie the establishment of dairy pastoralism in the Tibetan Plateau

BMC Biology, 2023
Background Domestication and introduction of dairy animals facilitated the permanent human occupation of the Tibetan Plateau. Yet the history of dairy pastoralism in the Tibetan Plateau remains poorly understood.
Min-Sheng Peng, Yan-Hu Liu, Quan-Kuan Shen, Xiao-Hua Zhang, Jiajia Dong, Jin-Xiu Li, Hui Zhao, Hui Zhang, Xiaoming Zhang, Yaoxi He, Hong Shi, Chaoying Cui, Ouzhuluobu, Tian-Yi Wu, Shi-Ming Liu, Gonggalanzi, Baimakangzhuo, Caijuan Bai, Duojizhuoma, Ti Liu, Shan-Shan Dai, Robert W. Murphy, Xue-Bin Qi, Guanghui Dong, Bing Su, Ya-Ping Zhang   +25 more
doaj   +1 more source

Population genomics on the origin of lactase persistence in Europe and South Asia

bioRxiv, 2020
The C to T mutation at rs4988235 located upstream of the lactase (LCT) gene is the primary determinant for lactase persistence (LP) that is prevalent among Europeans and South Asians. Here, we review evolutionary studies of this mutation based on ancient
Y. Satta, N. Takahata
semanticscholar   +1 more source

Homozygosity for a variant in SLC10A2 and infancy onset severe fat‐soluble vitamin deficiency due to bile acid malabsorption

JPGN Reports, Volume 6, Issue 3, Page 296-299, August 2025.
Abstract We present a case of a young female patient with persistent and severe fat‐soluble vitamin deficiency since infancy. Despite extensive investigations during childhood, the underlying cause remained elusive. The patient was generally asymptomatic while receiving continuous vitamin subsidy.
Christine Rungoe, Stefan Stender, Nawar Dalila, Emil D. Bartels, Christian Jakobsen   +4 more
wiley   +1 more source

Excellent agreement between genetic and hydrogen breath tests for lactase deficiency and the role of extended symptom assessment [PDF]

, 2017
Clinical manifestations of lactase (LCT) deficiency include intestinal and extra-intestinal symptoms. Lactose hydrogen breath test (H2-BT) is considered the gold standard to evaluate LCT deficiency (LD).
Behlis, Z., Eckardstein, A. v., Fried, M., Goetze, O., Hersberger, M., Pohl, D., Savarino, E., Stutz, B., Tutuian, R.   +8 more
core  

Структурно-функциональное состояние костной ткани у лиц молодого возраста с остеоартрозом в зависимости от уровня плазматического апелина и полиморфизма гена лактазы [PDF]

, 2017
В исследовании проведено детальное изучение влияния уровня содержания плазматического апелина-13 на развитие нарушений структурно-функционального состояния костной ткани у пациентов с остеоартрозом в зависимости от разных вариантов полиморфизма гена ...
Терешкин, К. И., Терешкина, Е. И.   +1 more
core   +2 more sources

Molecular Docking, Dynamics, and Preclinical Studies Reveal Morin Hydrate as a Potent PPARγ and Nrf2 Agonist That Mitigates Colon Inflammation

Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
ABSTRACT Peroxisome proliferator‐activated receptors (PPARs), functioning as nuclear receptors, regulate the expression of genes associated with inflammation, lipid metabolism, and glucose metabolism. The primary isotypes of PPARs are PPARα, PPARβ, and PPARγ. PPARγ is mostly expressed in adipose tissue and the colon.
Aya A. Touny, Balaji Venkataraman, Saeeda Almarzooqi, Rajesh B. Patil, Bhoomendra A. Bhongade, Miroslav Harjaček, Tahir A. Rizvi, Shreesh Ojha, Shamanth Neralagundi Harihar Gowdru, Sandeep B. Subramanya   +9 more
wiley   +1 more source