Структурно-функциональное состояние костной ткани у лиц молодого возраста с остеоартрозом в зависимости от уровня плазматического апелина и полиморфизма гена лактазы [PDF]
В исследовании проведено детальное изучение влияния уровня содержания плазматического апелина-13 на развитие нарушений структурно-функционального состояния костной ткани у пациентов с остеоартрозом в зависимости от разных вариантов полиморфизма гена ...
Терешкин, К. И. +1 more
core +2 more sources
Background Domestication and introduction of dairy animals facilitated the permanent human occupation of the Tibetan Plateau. Yet the history of dairy pastoralism in the Tibetan Plateau remains poorly understood.
Min-Sheng Peng +25 more
doaj +1 more source
Evolution of transcriptional enhancers and animal diversity [PDF]
Deciphering the genetic bases that drive animal diversity is one of the major challenges of modern biology. Although four decades ago it was proposed that animal evolution was mainly driven by changes in cis-regulatory DNA elements controlling gene ...
Rubinstein, Marcelo +1 more
core +1 more source
Background/Aims: Polymorphisms in the enhancer of the lactase gene (LCT) are strongly associated with lactase persistence, but not always predictive of the phenotype.
Luana Caroline Oliveira +3 more
doaj +1 more source
Excellent agreement between genetic and hydrogen breath tests for lactase deficiency and the role of extended symptom assessment [PDF]
Clinical manifestations of lactase (LCT) deficiency include intestinal and extra-intestinal symptoms. Lactose hydrogen breath test (H2-BT) is considered the gold standard to evaluate LCT deficiency (LD).
Behlis, Z. +8 more
core
Positive selection on loci associated with drug and alcohol dependence [PDF]
Much of the evolution of human behavior remains a mystery, including how certain disadvantageous behaviors are so prevalent. Nicotine addiction is one such phenotype.
Brooks, Andy +8 more
core +5 more sources
Sahelian pastoralism from the perspective of variants associated with lactase persistence.
OBJECTIVES Archeological evidence shows that first nomadic pastoralists came to the African Sahel from northeastern Sahara, where milking is reported by ~7.5 ka.
Edita Priehodová +7 more
semanticscholar +1 more source
Did Down‐Regulated Instincts Enable Human Gene‐Culture Coevolution?
ABSTRACT The unique intellectual and cultural attributes of Homo sapiens that arose during the Middle Stone Age are often ascribed to positive evolutionary development of novel physical or personality traits, but attempts to correlate cultural with genetic evolution have been unsuccessful.
Gerald E. Loeb
wiley +1 more source
Management and Modification of Flavonoids Against Nonalcoholic Fatty Liver Disease
Flavonoids protect against NAFLD by enhancing mitochondrial function, reducing ER stress, and modulating gut microbiota. Structural modifications improve flavonoid efficacy, offering a promising dietary strategy for NAFLD management. ABSTRACT Flavonoids are small bioactive molecules commonly found in plant‐derived foods, exhibiting antioxidant, anti ...
Weidong Bai +6 more
wiley +1 more source
The Role of Lactose Tolerance in Pre-Colonial Development [PDF]
This paper establishes a link between natural selection since the Neolithic Revolution and economic conditions in the pre-colonial era. The ability to digest milk, or to be lactose tolerant, is conferred by a gene variant, which is unequally distributed ...
Charles J. Cook
core

