Results 11 to 20 of about 399,657 (248)

Effect of mevalonate, zoledronate and BCG on monocyte/macrophage phenotype

Сибирский научный медицинский журнал, 2023
Cells of innate immunity, mainly monocytes/macrophages, form a long-term nonspecific immunological memory during the initial encounter with the pathogen, the so-called trained immunity.
A. P. Lykov, S. N. Belogorodtsev, E. K. Nemkova, A. Vetlugina, T. M. Terekhova, Ya. Sh. Schwartz   +5 more
doaj   +1 more source

Lactylation in tumor: mechanisms and therapeutic potentials

Frontiers in Immunology
Lactate, a central product of glucose metabolism, plays a vital role in energy supply and signal transduction, and it also participates in gene transcription regulation through lactylation.
Dandan Wang, Hao Rong, Ke Ma, Jun Peng
doaj   +1 more source

Potential source of bias in AI models: lactate measurement in the ICU in sepsis patients as a template

Frontiers in Medicine
ObjectiveHealth inequities may be driven by demographics such as sex, language proficiency, and race-ethnicity. These disparities may manifest through likelihood of testing, which in turn can bias artificial intelligence models.
Pratiksha Pradhan, Pratiksha Pradhan, Fredrik Willumsen Haug, Fredrik Willumsen Haug, Nebal S. Abu Hussein, Nebal S. Abu Hussein, Dana Moukheiber, Lama Moukheiber, Mira Moukheiber, Sulaiman Moukheiber, Luca Leon Weishaupt, Jacob G. Ellen, Helen D'Couto, Ishan C. Williams, Leo Anthony Celi, Leo Anthony Celi, Leo Anthony Celi, Joao Matos, Joao Matos, Joao Matos, Tristan Struja, Tristan Struja, Tristan Struja   +22 more
doaj   +1 more source

Lactate and lactylation in breast cancer: current understanding and therapeutic opportunities

Cancer Biology & Medicine
Breast cancer (BC) has the highest prevalence among cancers specific to women, and its incidence rates are increasing in many countries. Subtypes of BC, including HER2-positive or triple-negative BC, exhibit differing treatment responses; consequently ...
Lan Huang, Xuemei Chen, Meina Yan, Ze Xiang, Jian Wu   +4 more
doaj   +1 more source

Sympathy Lactation [PDF]

Journal of Perinatal Education, 2009
In this humor column, a childbirth educator describes assisting a parent and her young children with boarding an airplane.
openaire   +2 more sources

Research progress on the interaction between glucose metabolic reprogramming and lactylation in tumors

Frontiers in Immunology
Glucose metabolic reprogramming describes the alterations in intracellular metabolic pathways in response to variations in the body’s internal environment. This metabolic reprogramming has been the subject of extensive research.
Yi Yang, Yi Yang, Yi Wu, Yi Wu, Hui Chen, Hui Chen, Zehai Xu, Zehai Xu, Ruisi Lu, Ruisi Lu, Sijie Zhang, Sijie Zhang, Rui Zhan, Rui Zhan, Qinghua Xi, Qinghua Xi, Yunfeng Jin, Yunfeng Jin   +17 more
doaj   +1 more source

Evaluation of Clinical and Laboratory Prognostic Risk Factors in Organophosphate or Carbamate-Poisoned Pediatric Patients

Eurasian Journal of Emergency Medicine, 2021
Aim:We aimed to determine the clinical and demographic features of pediatric patients monitored at our hospital after organophosphate or carbamate intoxication.
Mehmet Açıkgöz
doaj   +1 more source

Energetic Contributions Including Gender Differences and Metabolic Flexibility in the General Population and Athletes

Metabolites, 2022
Metabolic flexibility includes the ability to perform fat and carbohydrate oxidation, as well as oxidative capacity, which is associated with mitochondrial function, energetic contributions, and physical health and performance. During a session of graded
Woo-Hwi Yang, Jeong-Hyun Park, So-Young Park, Yongdoo Park   +3 more
doaj   +1 more source

High level of intraoperative lactate might predict acute kidney injury in aortic arch surgery via minimally invasive approach in patients with type A dissection

Frontiers in Cardiovascular Medicine, 2023
BackgroundA high incidence of acute kidney injury (AKI) has been recorded in total arch replacement (TAR) combined with frozen elephant trunk (FET) implantation in patients with acute type A dissection (ATAAD) via median sternotomy approach with some ...
Ying Lyu, Yu Liu, Xiong Xiao, Xiong Xiao, Zhonglu Yang, Yuguang Ge, Hui Jiang   +6 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source