Natural compounds as lactate dehydrogenase inhibitors: potential therapeutics for lactate dehydrogenase inhibitors-related diseases [PDF]
Frontiers in Pharmacology, 2023 Lactate dehydrogenase (LDH) is a crucial enzyme involved in energy metabolism and present in various cells throughout the body. Its diverse physiological functions encompass glycolysis, and its abnormal activity is associated with numerous diseases ...
Jung Ho Han +5 more
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Elevated lactate dehydrogenase – A red herring in the diagnosis of a sclerosing stromal tumor: A case report [PDF]
Case Reports in Women's HealthSclerosing stromal tumors are a rare type of ovarian tumor in the category of sex cord stromal tumors, which arise from the ovarian connective tissue.
Kelly Devlin +3 more
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Serum lactate dehydrogenase is associated with impaired lung function: NHANES 2011-2012.
PLoS ONE, 2023 BackgroundSerum lactate dehydrogenase levels reflect disease status in a variety of organs, but its role in indicating pulmonary function is not yet clear.
Sheng Hu +9 more
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Characterization of the L-lactate dehydrogenase from Aggregatibacter actinomycetemcomitans. [PDF]
PLoS ONE, 2009 Aggregatibacter actinomycetemcomitans is a Gram-negative opportunistic pathogen and the proposed causative agent of localized aggressive periodontitis. A.
Stacie A Brown, Marvin Whiteley
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Homology modelling and docking analysis of L-lactate dehydrogenase from Streptococcus thermopilus [PDF]
Acta Periodica Technologica, 2016 The aim of this research was to create a three-dimensional model of L-lactate dehydrogenase from the main yoghurt starter culture - Streptococcus thermopilus, to analyse its structural features and investigate substrate binding in the active ...
Vukić Vladimir R. +4 more
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Clinical observations of Leber hereditary optic neuropathy with and without neurological symptoms [PDF]
Анналы клинической и экспериментальной неврологии, 2022 Three case studies of adults with Leber hereditary optic neuropathy with and without neurological symptoms are presented. An elevated blood lactate level and changes in the activity of the mitochondrial enzymes in peripheral blood lymphocytes were noted.
Sergey V. Kotov +4 more
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Cerium (III) and (IV) containing mesoporous glasses/alginate beads for bone regeneration: bioactivity, biocompatibility and reactive oxygen species activity [PDF]
Materials for Biological Applications. 105, 109971. 2019, 2021 A very small number of biomaterials investigated for bone regeneration was reported as able to prevent the oxidative stress. In this study beads based on alginate hydrogel and mesoporous glasses (MG) containing different amounts of cerium oxides (Ce3+/Ce4+) exhibiting antioxidant properties were investigated as a good approach to mimic the action of ...
arxiv +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 The oxidation of NADH with the concomitant reduction of a quinone is a crucial step in the metabolism of respiring cells. In this study, we analyzed the relevance of three different NADH oxidation systems in the actinobacterial model organism ...
Tomoya Maeda +2 more
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Journal of Pharmacy and Bioallied Sciences, 2022 Lactate dehydrogenase enzyme (LDH) helps in the conversion of glucose into pyruvic acid during aerobic glycolysis and is found in the cytoplasm of most cells in the human body. When oxidative stress occurs in the body, LDH may be released extracellularly and its level is usually indicative of the severity of tissue damage. LDH
Pandarathodiyil, Anitha Krishnan +6 more
openaire +2 more sources
Activity of lactate dehydrogenase and superoxide dismutase in the circulation of patients with breast carcinoma [PDF]
Archive of Oncology, 2008 Background: A rapid increase in the turnover of malignant cells modulates the enzymes level in circulation and may be a prognostic sign of disease progression.
Bogdanović Gordana +9 more
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