Results 171 to 180 of about 379,267 (388)

Evaluation of Red Cell Transfusion Effects on Tissue Oxigenation, Based on Blood Lactate Levels As Sensitive Indicator of Tissue Oxygenation

open access: diamond, 2015
M Lordian Nunci   +86 more
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Physical and Functional Association of Lactate Dehydrogenase (LDH) with Skeletal Muscle Mitochondria [PDF]

open access: hybrid, 2013
Pía A. Elustondo   +5 more
openalex   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

open access: yesAdvanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang   +7 more
wiley   +1 more source

Technical note: Validation of sensor-recorded lying bouts in lactating dairy cows using a 2-sensor approach [PDF]

open access: bronze, 2015
A. Kok   +5 more
openalex   +1 more source

Rapid Remodeling of the Human Gut Microbiome in Response to Short‐Term Animal Product Restriction and Associations with Host Molecular Phenotypes

open access: yesAdvanced Science, EarlyView.
A real‐world model of structured animal product restriction practiced for religious reasons reveals the dynamic adaptability of the human gut microbiome to dietary change and uncovers reductions in diversity and rare taxa loss. Integrated microbiome, metabolomic, and proteomic analyses uncover coordinated taxonomic and molecular shifts and identify ...
Christina Emmanouil   +7 more
wiley   +1 more source

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