Results 151 to 160 of about 318,888 (340)

Ultrathin 2D In2O3 Nanosheets Confining Cu Single Atoms Synergized With Oxygen Vacancies for High Selectivity of Photocatalytic Reduction of CO2 to CO

open access: yesAdvanced Science, EarlyView.
In this work, we constructed an ultrathin two‐dimensional (2D) In2O3 nanosheet (In2O3‐Ns) structure based on oxygen vacancies (OV)‐rich defects and low crystallinity to anchor Cu single atoms (Cu SAs) and synthesized Cu/In2O3‐Ns photocatalysts. ABSTRACT In this work, we constructed an ultrathin two‐dimensional (2D) In2O3 nanosheet (In2O3‐Ns) structure ...
Yueying Yang   +10 more
wiley   +1 more source

AARS1‐Mediated H3K27 Lactylation Rewires Glycolysis to Sustain Aggressive and Recurrent Bladder Cancer

open access: yesAdvanced Science, EarlyView.
AARS1 drives PI3K–AKT–mTOR‐dependent glycolysis in bladder cancer, promoting lactate accumulation, increased lactylation, H3K27la enrichment at the HK2 promoter, and HK2 transcription. HK2 reinforces glycolysis, sustaining a metabolic–epigenetic program associated with tumor progression, recurrence, and metastasis.
Qin Yuan   +13 more
wiley   +1 more source

Severity and timing of elevated lactate correlates with mortality after cardiac surgery. [PDF]

open access: yesJ Thorac Cardiovasc Surg
Delay TK   +8 more
europepmc   +1 more source

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

open access: yesAdvanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian   +12 more
wiley   +1 more source

Peak Lactate During the First Postoperative Day Predicts 90-Day Graft Loss After Liver Transplantation. [PDF]

open access: yesJ Clin Med
Lai Q   +9 more
europepmc   +1 more source

Ames Laboratory, Iowa State University (IS) Report IS-621

open access: yes, 1963
From Abstract : "The solubilities of the individual rare earth lactates and α-hysroxyisobutyrates in water at 20 and 60° were determined for comparison with the rare earth glycolate solubilities determined earlier.
Powell, J. E.   +3 more
core  

Cancer‐Associated Fibroblasts Promote Glucose Metabolic Reprogramming and Progression of Triple‐Negative Breast Cancer via Exosomal circFAD104‐Mediated Intercellular Communication

open access: yesAdvanced Science, EarlyView.
CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang   +16 more
wiley   +1 more source

CORRELATION OF THE PROGNOSTIC INDICATORS OF A BRAIN INJURY AT THE BIRTH AND THE OUTCOME OF THE NEWBORNS [PDF]

open access: yes
Background: To investigate the impact of blood acid-base disorders and elevated lactate during birth on the final outcome of the newborn.Subjects and methods: The study include 110 children born with acid-base imbalance and increased level of lactates at
Jerković Raguž, Marjana   +3 more
core   +1 more source

Perioperative Carbon Dioxide Gap Following Crystalloid and Colloid Therapy in Neurosurgical Patients: A Randomised Comparative Study

open access: yesJK Science
Background: The carbon dioxide gap (CO2‚ gap) is a flow-dependent variable inversely related to cardiac output and has emerged as a potential marker of circulatory adequacy.
Manisha Manohar   +5 more
doaj  

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