Results 211 to 220 of about 318,888 (340)

Granzyme B PET Imaging Reveals Lgmn+ Macrophage‐Mediated Immune Evasion and Guides Immunotherapy in EGFR‐TKI‐Resistant NSCLC

Advanced Science, EarlyView.
Graphical illustration of 68Ga‐GZB PET/CT imaging reveals immune dynamics post‐EGFR‐TKI resistance in NSCLC; Lgmn+ macrophages‐derived Lgmn‐containing extracellular vesicles inhibit glycolysis, induce CD8+ T cell exhaustion, and targeting Lgmn restores immunotherapy sensitivity.
Dongliang Wang, Wenqin Luo, Qiufang Liu, Wenxuan Tang, Bin Zhu, Jiwei Chen, Qian Zhou, Shuang Tang, Xiaoping Xu, Shaoli Song   +9 more
wiley   +1 more source

Massive envenomations by bees in French Guiana: A ten-year retrospective study (2014-2023). [PDF]

PLoS Negl Trop Dis
Blaud R, Mutricy R, Negrello F, Eeckhout M, Epelboin L, Douine M, Kallel H, Fremery A.   +7 more
europepmc   +1 more source

Conformational change of an amylose derivative in chiral solvents: amylose tris(n-butylcarbamate) in ethyl lactates

, 2012
Shota Arakawa, Ken Terao, S. Kitamura, Takahiro Sato   +3 more
semanticscholar   +1 more source

Hierarchical Nanoplatform Integrating Oxidative–Acidic Microenvironment Remodeling and Bone Homeostasis Modulation for Diabetic Bone Defect Therapy

Advanced Science, EarlyView.
A hierarchical CM/LDH nanoplatform integrates ROS‐scavenging Ce‐MOF nanozymes with acid‐neutralizing CaAl‐LDH and is delivered within GelMA hydrogel to diabetic bone defects. By remodeling the oxidative‐acidic microenvironment, preserving mitochondrial homeostasis, and suppressing mtDNA–cGAS–STING inflammatory signaling, CM/LDH reduces proinflammatory ...
Xu Chen, Xingyu Zhu, Zhixin Qiu, Yijia Zhu, Xinhui Zheng, Dongqi Fan, Jinglei Zhan, Congxiu Mao, Ping Ji, Tao Chen, Qingqing He   +10 more
wiley   +1 more source

Multienzyme cascade biotransformation of L-Tyrosine to Danshensu by engineered Escherichia coli. [PDF]

PLoS One
Xiong T, Li S, Li X, Li X, Wu M, Liu J, Guo J, Li X.   +7 more
europepmc   +1 more source

Antimicrobial Effects of Lactates: A Review.

Journal of Food Protection, 1994
L. Shelef
semanticscholar   +1 more source

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

Advanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann, Adam Brooks Goodman, Myddelton C. Parker, Mark Garren, Ji Eun Park, Chad Schmiedt, Hitesh Handa, Elizabeth J. Brisbois   +7 more
wiley   +1 more source

Host metabolism can produce many indoles and phenols independently of the microbiome. [PDF]

Nat Metab
AbuSalim JE, Olszewski K, Youssef S, Mitchell SJ, Hunter CJ, Little J, Sidebottom A, Boyer JA, Knutson SD, Samarah LZ, MacArthur MR, Henneberg AL, Ryseck RP, Opitz CA, MacMillan DWC, Donia MS, Pamer EG, Imam S, Lehmann CJ, Odenike O, Rabinowitz JD.   +20 more
europepmc   +1 more source

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

Advanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong, Chaochao Luo, Zezheng Liu, Xinyan Zhang, Daixu Jia, Yang Sun, Zhaonan Zhang, Haoran Shi, Jianfang Wang, Hua Zhang   +9 more
wiley   +1 more source