Results 171 to 180 of about 12,286,981 (307)

Effects of prepartum dietary cation-anion difference and source of vitamin D in dairy cows: Lactation performance and energy metabolism.

Journal of Dairy Science, 2017
N. Martinez, R. Rodney, E. Block, L. L. Hernandez, C. Nelson, I. Lean, J. E. Santos   +6 more
semanticscholar   +1 more source

Palmitoyl Acyltransferase Zdhhc17 Promotes Functional Recovery After Spinal Cord Injury by Targeting the Nuclear Transport Factors Kpna2 and Ipo9

Advanced Science, EarlyView.
In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen, Huan Chen, Sining Ding, Fan Liu, Xiaofei Zheng, Yuan Wang, Ruitu Tian, Huan Li, Peilin Liu, Le Hu, Bin Liu, Limin Rong, Mangmang Li   +12 more
wiley   +1 more source

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

Advanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang, Yunfeng Zheng, Chenfan Tian, Yuan Tu, Xiaoxia Chang, Jiaxin Yu, Hangkun Yu, Chunxia Gong, Jie Xiong, Philip N. Baker, Yong Fu, Chao Tong   +11 more
wiley   +1 more source

Effects of Fermented Palm Kernel Meal on Lactation Performance, Rumen Fermentation, Rumen Microbiota, and Rumen Metabolomic Profiles in Holstein Dairy Cows. [PDF]

Vet Sci
Zhang X, Guan X, Cao J, Yan Y, Zhao Y, Mao H, Ma L, Huang L, Tang X, Jiang S, Li Y.   +10 more
europepmc   +1 more source

Relationships between early-life growth, intake, and birth season with first-lactation performance of Holstein dairy cows.

Journal of Dairy Science, 2017
H. Chester-Jones, B. Heins, D. Ziegler, D. Schimek, S. Schuling, B. Ziegler, M. D. de Ondarza, C. Sniffen, N. Broadwater   +8 more
semanticscholar   +1 more source

Magnetically Guided Macrophage Immunobots Coordinate Iron‐Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy

Advanced Science, EarlyView.
Magnetically guided macrophage immunobots integrate active tumor targeting with immunometabolic therapy. After systemic administration, magnetic actuation enhances immunobot retention and tumor penetration, while LPS‐functionalized FePt microrollers sustain M1‐like polarization through inflammatory and iron‐amplified oxidative signaling and trigger ...
Xirui Zeng, Yingfei Zhang, Chong Wu, Qijia Duan, Mengqi Fan, Kuan Wang, Shirong Cai, Immihan Ceren Yasa   +7 more
wiley   +1 more source

Forage particle size, rather than dietary iNDF concentration, affects chewing activity and lactation performance in lactating dairy goats. [PDF]

Vet Anim Sci
Soufizadeh M, Pirmohammadi R, Alijoo YA, Khalilvandi-Behroozyar H, Asadnezhad B, Salem AZM.   +5 more
europepmc   +1 more source

Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis

Advanced Science, EarlyView.
Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran, Yanchun Fang, Shengming Ruan, Juling Wang, Songbai Liu, Yuan Mao, Dongsheng Hou, Yanping Wang, Zi Ye, Qiong Li, Daoxiang Zhang   +10 more
wiley   +1 more source

Multi-omics revealed the effects of rumen to blood path on early lactation performance in transition dairy cows. [PDF]

Microbiome
Tang G, Zhang C, Zhang X, Liu H, Suen G, Yao J, Zhang J.   +6 more
europepmc   +1 more source

Extending the duration of the voluntary waiting period from 60 to 88 days in cows that received timed artificial insemination after the Double-Ovsynch protocol affected the reproductive performance, herd exit dynamics, and lactation performance of dairy cows.

Journal of Dairy Science, 2018
M. Stangaferro, R. Wijma, M. Masello, Mark J. Thomas, J. Giordano   +4 more
semanticscholar   +1 more source