Results 71 to 80 of about 35,500 (218)
Vitamin B1 for type B metabolic acidosis: An underrecognized approach
Lactic acidosis is a life-threatening and rather common complication and reason for consultation to the nephrologist. The cause for this condition is usually thought to be secondary to hypoperfusion and ischemia collectively.
Adriana Dejman, Jason Riveros
doaj +1 more source
Abstract Background Although previous experimental studies showed that metabolic acidosis promoted muscle catabolism and impaired protein synthesis, few epidemiological studies reported an independent association between serum bicarbonate levels and muscle atrophy in patients with chronic kidney disease (CKD).
Nobuhisa Morimoto +13 more
wiley +1 more source
Summary Introduction Surgery in patients with diabetes mellitus is associated with increased morbidity and mortality compared with those who do not have diabetes mellitus. This is likely multifactorial and could be attributed to organisational issues; dysglycaemia; hospital‐acquired diabetic ketoacidosis; errors with insulin prescribing and ...
Nicholas A. Levy +19 more
wiley +1 more source
ABSTRACT Aims Evogliptin, a dipeptidyl peptidase‐4 inhibitor with a glucose‐dependent mechanism of action, is widely used as a monotherapy or in combination with other agents. However, observational studies in routine clinical settings remain limited.
Jun Hwa Hong +14 more
wiley +1 more source
Lactate and colic–Shetland ponies as an example of one size does not fit all
Summary The clinical commentary discusses the utility of peritoneal lactate alone, and in the context of other clinical factors, in determining the presence of a strangulating intestinal obstruction. A current study on Shetland ponies has revealed that peritoneal lactate well outside the range typically to be considered at risk of strangulating ...
A. T. Blikslager
wiley +1 more source
Lactic Acidosis in Asthma: Report of Two Cases and Review of the Literature
Lactic acidosis is commonly associated with states of hypoxia and decreased tissue perfusion. Elevated lactic acid levels have also been observed in individuals who are not septic and who are normotensive, but who have received systemic adrenergic ...
Suma Prakash, Sanjay Mehta
doaj +1 more source
Beyond the chaos: How architecture structures tumour biology
Tissue architecture shapes tumour initiation and progression through multiple interconnected layers continuously remodelled over time. This review outlines how physical forces, biochemical cues, cellular niches and systemic influences contribute to tumour evolution.
Lea Dörner +3 more
wiley +1 more source
Metformin-related acidosis in a woman while performing Haj: A conservative approach
Metformin is a first-line oral anti-hyperglycemic agent. It decreases insulin resistance, decreases hepatic glucose output and enhances peripheral glucose uptake. Metformin is used as a monotherapy in combination with other oral hypoglycemic agents.
Riyazuddin S. H. Ansari +5 more
doaj +1 more source
Tofogliflozin was compared with metformin in treatment‐naïve people with type 2 diabetes for 4 weeks. Overall insulin secretory capacity did not improve; however, tofogliflozin was associated with an improved disposition index in individuals with poorer baseline glucose tolerance or greater improvement after treatment.
Maiko Miyamoto +39 more
wiley +1 more source
Severe Type B Lactic Acidosis in a Rare and Aggressive HIV-Related Lymphoma
We describe the prognostic implication and aggressive clinical course of lymphoma-related lactic acidosis in a rare HIV-related lymphoma. Patient was diagnosed with plasmablastic lymphoma and developed severe lactic acidosis, and was treated on the ...
John Harwood Scott +4 more
doaj +1 more source

