Results 71 to 80 of about 215,605 (258)
Study enrollment and testing for lactic acidosis.
, 2016 Study enrollment and testing for lactic acidosis.
Karen E. S. Hamre (3185379) +3 more
core +1 more source
BMEMat, EarlyView.This review systematically summarizes the major molecular mechanisms governing TAM polarization and their coordinated interactions. It further highlights recent advances in nanoagonist‐based strategies that intervene in these pathways to reprogram TAMs, critically discussing their therapeutic potential, current limitations, and translational prospects.
Siqi Fang +7 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Regulatory limits on metformin co‐administered with dolutegravir (DTG) derive from healthy‐volunteer studies in which DTG increased metformin exposure by 79% through organic cation transporter 2 inhibition, prompting a 1,000 mg/day metformin dose restriction.
Rohan M. Benecke +3 more
wiley +1 more source
in vitro activation of complement and contact system by lactic acidosis
Mediators of Inflammation, 1998 The activation of complement and contact systems occurs in reperfusion injuries with initial tissue hypoxia, and lactic acidosis such as mycardial infarction and birth asphyxia.
J. Sonntag +3 more
doaj +1 more source
ACUTE KIDNEY INJURY DUE TO METFORMIN-ASSOCIATED LACTIC ACIDOSIS [PDF]
Journal of IMABIntroduction: Acute kidney injury is a clinical syndrome of rapid decline of renal function due to various causes and often occurs by more than one pathophysiological mechanism.
Svilena Aleksandrova +3 more
doaj +1 more source
Complex interplay between metformin, AKI and lactic acidosis [PDF]
, 2017 Debate exists regarding the safety of metformin and the risk of metformin-associated lactic acidosis, particularly in the setting of kidney dysfunction.
Rhee, Connie M +3 more
core +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes
Epilepsia Open, EarlyView.Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola +3 more
wiley +1 more source
Forage chemical composition drives early metabolic shifts in ponies fed different haylages
Equine Veterinary Journal, EarlyView.Abstract Background Rapid changes between feeds can cause dysbiosis and colic in horses. The metabolic consequences of transitioning between haylages (HY) are currently unknown. Objectives To characterise urinary and faecal metabonomics in ponies transitioned between HY varying in botanical composition and physiological age and to evaluate the speed of
M. J. S. Moore‐Colyer +2 more
wiley +1 more source
Clinical, haematobiochemical and ruminal changes during the onset and recovery of induced lactic acidosis in sheep [PDF]
Biotechnology in Animal Husbandry, 2014 A total number of five sheep were used in cross over design with an interval of three weeks for induction of lactic acidosis with sucrose, and treated with sodium bicarbonate as antacid, yeast as probiotics and gentian root powder as medicinal herbs. The
Zein-Eldin Mohamed M. +4 more
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