Results 71 to 80 of about 41,340 (258)

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Successful Treatment of Severe Type B Lactic Acidosis in a Patient with HIV/AIDS-Associated High-Grade NHL

Case Reports in Immunology, 2018
Type B lactic acidosis is a rare metabolic complication sometimes associated with hematologic malignancies. When present, this type of lactic acidosis is most commonly seen in patients with high-grade lymphomas or leukemias and is usually indicative of a
Marco Mejia, Ariel Perez, Harold Watson, Daniel Sanchez, Jorge Parellada, Mario Madruga, S. J. Carlan   +6 more
doaj   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

Lactic acidosis following heart transplantation: a common phenomenon?

, 2002
BACKGROUND Lactic acidosis (LAc) is a common form of metabolic acidosis early after heart transplantation (HTX). The mechanism remains unclear. This study analyzed 13 patients who developed severe LAc after HTX.
Thierry Carrel, Roger Hullin, Hans‐Ueli Tschanz, Carrel, Thierry, Paul Mohacsi, Hullin, Roger, Hildegard Tanner, Tanner, Hildegard, Giovanni Pedrazzini, Pedrazzinia, Giovanni, Mohacsi, Paul, Tschanz, Hans-Ueli   +11 more
core   +1 more source

Clinical, haematobiochemical and ruminal changes during the onset and recovery of induced lactic acidosis in sheep [PDF]

Biotechnology in Animal Husbandry, 2014
A total number of five sheep were used in cross over design with an interval of three weeks for induction of lactic acidosis with sucrose, and treated with sodium bicarbonate as antacid, yeast as probiotics and gentian root powder as medicinal herbs. The
Zein-Eldin Mohamed M., Ghanem M.M., El-Raof Abd Y.M., El-Attar H.M., El-Khaiat H.M.   +4 more
doaj  

ACUTE KIDNEY INJURY DUE TO METFORMIN-ASSOCIATED LACTIC ACIDOSIS [PDF]

Journal of IMAB
Introduction: Acute kidney injury is a clinical syndrome of rapid decline of renal function due to various causes and often occurs by more than one pathophysiological mechanism.
Svilena Aleksandrova, Stela Linkova, Yulia Benovska, Biser Borisov   +3 more
doaj   +1 more source

Carbon Dots for Cancer Theranostics: Synthesis Strategies, Luminescence Properties, and Advances in Bioimaging‐Guided Diagnosis and Therapy

Chemistry – A European Journal, EarlyView.
Lighting up the path to precision oncology: This review comprehensively summarizes the rational design of carbon dots (CDs), elucidating how core size, surface chemistry, and heteroatom doping dictate their luminescence mechanisms. Special emphasis is placed on engineering NIR‐II emissive CDs for deep‐tissue imaging.
Zekun Yan, Yupeng Liu, Jinyun Tan, Songnan Qu   +3 more
wiley   +1 more source

Factors associated with lactic acidosis in HIV patients on antiretroviral therapy in Harare city- 2012

, 2013
Introduction: Antiretroviral medicines have side effects that can be life threatening. An unpublished study by Malunga in Harare City, showed a high incidence of hyperlactatemia in patients on stalanev.
Choto, Emmaculate
core  

Lactic acidosis in diabetic ketoacidosis

, 2014
We describe the case of a 22-year-old man with insulin-dependent diabetes, who was admitted to the emergency department with hypotension, unconsciousness and a severe combined diabetic ketoacidosis (DKA) and lactic acid acidosis.
Boerma, E Christiaan, ter Avest, Ewoud, Kiewiet, Mink K P, Feenstra, Rieneke A   +3 more
core   +1 more source

Reversible Severe Acute Lactic Acidosis Caused by Thiamine Deficiency in Intensive Care Unit

Case Reports in Critical Care
Lactic acidosis is a common cause of metabolic acidosis in hospitalized patients. It is typically caused by hypoperfusion and anaerobic metabolism and is often associated with sepsis.
Jisu Hong, Daehong Cho, Hong Jun Kim, Jaemin Jo, Gil Myeong Seong   +4 more
doaj   +1 more source