Results 191 to 200 of about 231,861 (311)

Unlocking insights: Validating a comprehensive model for predicting spontaneous preterm delivery and microbial invasion in women facing preterm labor

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Preterm labor is a multifactorial syndrome with diverse etiologies such as infection, inflammation, uteroplacental dysfunction, stress, and immune dysregulation. Identifying women at high risk remains a challenge, and multivariate prediction models have been developed to enhance risk stratification.
Ester del Barco   +12 more
wiley   +1 more source

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

open access: yesiMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia   +11 more
wiley   +1 more source

Cervical cancer patients' vaginal microbiome and metabolites: research progress and clinical applications. [PDF]

open access: yesFront Microbiol
Huang Q   +10 more
europepmc   +1 more source

Advances in Immunological Combination Therapy for Colorectal Cancer

open access: yesiMetaMed, EarlyView.
Review the progress of combined immunotherapy for colorectal cancer. ABSTRACT Immune checkpoint inhibitors (ICIs) have been utilized extensively and shown to be therapeutically beneficial in the treatment of solid tumors in recent years. Nonetheless, considerable heterogeneity in Colorectal cancer (CRC) requires careful consideration.
Jiayue Wu   +7 more
wiley   +1 more source

N6‐Methyladenosine in Inflammatory Bowel Disease: An Emerging Regulator of Pathogenesis and a Novel Therapeutic Frontier

open access: yesiMetaMed, EarlyView.
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the intestine associated with an imbalance in intestinal homeostasis. m6A‐modifying enzymes, consisting of m6A writers, erasers and readers, plays a pivotal role in the pathogenesis and progression of IBD by affecting four intestinal barriers, including the intestinal mechanical ...
Jiaxian Guo   +4 more
wiley   +1 more source

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