Results 211 to 220 of about 446,798 (339)

Ginseng polysaccharides prevent mastitis through Lactobacillus murinus‐derived deoxycholic acid and TGR5 signaling

iMetaOmics, EarlyView.
Prebiotic Ginseng polysaccharides (GP) alleviate mastitis through selective enrichment of gut L. murinus, which elevates its anti‐inflammatory metabolite deoxycholic acid (DCA). Circulating DCA engages mammary epithelial TGR5 receptors, triggering the cAMP–PKA pathway to suppress NF‐κB/NLRP3‐mediated inflammation.
Zhijie Zheng, Huiying Liu, Sizhe Chen, Jianhui Gu, Sisi Cai, Xiang Liu, Raphaela I. Lau, Yao Zhang, Sunjae Lee, Xiaoyan Wang, Kewei Fan, Xiaole Yin, Hein Min Tun, Renyou Gan, Haichong Wu, Qi Su   +15 more
wiley   +1 more source

The interplay between probiotics and mast cells in gut inflammation: a mini-review. [PDF]

Front Cell Infect Microbiol
Herrera-Saldivar MF, Hernandez-Bautista NC, Quiroga-Garza JM, Vazquez-Guillen JM, Chacon-Salinas R, Rojas-Contreras M, Vazquez-Juarez R, Resendez-Perez D, Tamez-Guerra RS, Rodriguez-Padilla C.   +9 more
europepmc   +1 more source

Beyond “you are what you eat”: Unlocking gut microbiota‐mediated biotransformation of dietary phytochemicals

iMetaOmics, EarlyView.
The “efficacy paradox” of phytochemicals, low bioavailability yet significant health benefits, is associated with gut microbiota, which biotransforms dietary precursors into bioactive metabolites, enabling systemic effects. Thus, health outcomes of diet depend not just on intake “the rainbow”, but on gut microbial metabolism, redefining “you are what ...
Peng Yang, Ren‐You Gan
wiley   +1 more source

Effect of Probiotic and Synbiotic Oral Supplementation in Autoimmune Diseases: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Nutrients
Chiou YY, Chiu TY, Chen MJ.
europepmc   +1 more source

Accu16S/AccuITS: Accurate and broadly applicable amplicon sequencing for absolute microbiome quantification

iMeta, EarlyView.
Traditional 16S rRNA gene and Internal Transcribed Spacer region amplicon sequencing provides only relative abundance, often leading to biased ecological interpretations. To overcome this limitation, we developed Accu16S/AccuITS, an absolute quantification method for bacterial and fungal amplicons based on synthetic internal spike‐in DNA with known ...
Defeng Bai, Ou Fang, Caihua Li, Bin Cai, Xingyan Tan, Mengmeng Jiang, Bin Gan, Jinxia Fu, Yunyun Gao, Ying Wang, Yong‐Xin Liu   +10 more
wiley   +1 more source

Recent advances on fermentation of mustard plant (<i>Brassica juncea</i> L.): microbial community, fermentation processing and sensorial quality: a review. [PDF]

Front Microbiol
Diao N, Cai A, Zhou Y, Long B, Mo Z, Shang S, Liu Y, Xu J, Hu W, Feng K, Sarengaowa.   +10 more
europepmc   +1 more source

Chondroitin sulfate restores muscle mass via gut–muscle axis remodeling through sugar–bile acid metabolism reprogramming

iMeta, EarlyView.
The graphical abstract illustrates the molecular mechanism by which chondroitin sulfate (DCS) alleviates glucocorticoid‐induced myopathy through the gut–muscle axis. DCS selectively enriches L. johnsonii Z‐RW, enhancing bshA‐encoded BSH activity to promote bile acid deconjugation and reduce the sugar–bile acid ratio, thereby re‐establishing intestinal ...
Ruiyun Wu, Tao Wen, Nan Shang, Penghao Xie, Zhenyu Wang, Hang Li, Shaobo Li, Dequan Zhang   +7 more
wiley   +1 more source

Lactobacillus casei culture supernatant ameliorates acute alcohol-induced liver injury by inhibiting cellular stress and promoting intestinal integrity in mice. [PDF]

PLoS One
Zhang X, Xu Z, You Y, Xie L, Jiang Y, Chen J, Xu Z, Xu F, Zhou D.   +8 more
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Meta-analysis of probiotic effects on broiler performance: Bacillus outperforms Lactobacillus with enhanced and longer efficacy in developing regions. [PDF]

Poult Sci
Bilal M, El-Fateh M, Arfan HM, Zhao X.
europepmc   +1 more source