Results 51 to 60 of about 83,342 (317)

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Engineered Lactococcus lactis secreting Flt3L and OX40 ligand for in situ vaccination-based cancer immunotherapy

Nature Communications, 2022
The probiotic Lactococcus lactis has been used for the delivery of therapeutic molecules. Here the authors engineer Lactococcus lactis to express a fusion protein of Flt3L and OX40 ligand, eliciting anti-tumor immune response in preclinical cancer models.
Junmeng Zhu, Yaohua Ke, Qin Liu, Ju Yang, Fangcen Liu, Ruihan Xu, Hang Zhou, Aoxing Chen, Jie Xiao, Fanyan Meng, Lixia Yu, Rutian Li, Jia Wei, Baorui Liu   +13 more
doaj   +1 more source

Proton Motive Force-Dependent Hoechst 33342 Transport by the ABC Transporter LmrA of Lactococcus lactis [PDF]

, 2005
The fluorescent compound Hoechst 33342 is a substrate for many multidrug resistance (MDR) transporters and is widely used to characterize their transport activity.
Abbreviations ABC, Chen M., Doerrler W. T., Ecker G. F., Gajic O., Haugland R. P., Higuchi R., Ketchum C. J., Kuipers O. P., Lalande M. E., Lanzetta P. A., Lewinson O., Linnett P. E., Lubelski J., Lubelski J., Margolles A., Mazurkiewicz P., Orelle C., Paternostre M. T., Poelarends G. J., Putman M., Sakamoto K., Sambrook J., Shapiro A. B., Shapiro A. B., Shapiro A. B., Shapiro A. B., Sharma S., Steinfels E., Urbatsch I. L., van Veen H. W., van Veen H. W., van Veen H. W., Venter H., Viitanen P., Yu J. L.   +35 more
core   +2 more sources

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Lactococcus lactis endocarditis and liver abscess in an immunocompetent patient: a case report and review of the literature

Journal of Medical Case Reports, 2023
Background Over the last two decades, several cases of infections caused by Lactococcus lactis have been reported. This Gram-positive coccus is considered non-pathogenic for humans.
Wahib Lahlou, Abderrahim Bourial, Taib Maaouni, Ahmed Bensaad, Ilham Bensahi, Mohamed Sabry, Mohamed Miguil   +6 more
doaj   +1 more source

Targeting the Microbiota to Address Diet-Induced Obesity: A Time Dependent Challenge [PDF]

, 2013
peer-reviewedLinks between the gut microbiota and host metabolism have provided new perspectives on obesity. We previously showed that the link between the microbiota and fat deposition is age- and time-dependent subject to microbial adaptation to diet ...
Clarke, Siobhan F., Cotter, Paul D., Murphy, Eileen F., O'Sullivan, Orla, O'Toole, Paul W., Ross, R Paul, Shanahan, Fergus   +6 more
core   +3 more sources

NGS analysis revealed that Lactococcus garvieae Lg‐Per was Lactococcus petauri in Türkiye

Journal of Fish Diseases, 2022
AbstractLactococcus garvieae Lg‐per was originally isolated from rainbow trout cultured in cages located on the Turkish coast of the Black Sea in 2011. A whole genome sequence of Lg‐per was performed in the present study. The complete genome of Lg‐per mapped to the reference genomes of L.
Ilhan Altinok, Rafet Cagri Ozturk, Mustafa Ture   +2 more
openaire   +3 more sources

Ameliorating Shelf Life and Physicochemical Characteristics of UF White Soft Cheese Using Free or Microencapsulated Lb. rhamnosus and Lb. paracasei as a Sustainable Food System

Food Chemistry International, EarlyView.
This study investigates some practical technological insights that can be used for development and production of UF white soft cheese using free or microencapsulated Lb. rhamnosus and Lb. paracasei. ABSTRACT The present research aimed to ameliorate the shelf life of UF white soft cheese made from buffalo's milk retentate. To achieve this proposal, five
Adel Mahmoud Mohamed Kholif, Ahmed Moawad Mabrouk, Sherein Ismail Abd El‐Moez   +2 more
wiley   +1 more source

Peptide metabolism in the lactococci and its regulation : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

, 1994
Aspects of peptide metabolism in the lactococci have been investigated to increase the understanding of how these nutritionally fastidious bacteria, which have a central role in the dairy manufacturing industry, are able to grow in a complex medium such ...
Moore, Ian Linton
core  

From DNA sequence to application: possibilities and complications [PDF]

, 1999
The development of sophisticated genetic tools during the past 15 years have facilitated a tremendous increase of fundamental and application-oriented knowledge of lactic acid bacteria (LAB) and their bacteriophages.
A Bruttin, A Bruttin, A Kraus, A Nauta, A Nauta, A Nauta, A Sazicu, AK Aggarwal, B Christiansen, B Christiansen, BC Lokman, BC Lokman, BM Chassy, C Delorme, C Hill, C Schouler, CA Alpert, CA Shearman, CJ Hueck, CO Pabo, CT Verrips, D Botstein, D Lillehaug, D Lillehaug, D Sinderen, DJ O’Sullivan, DJ O’Sullivan, DO Gostick, DO Gostick, E Küster, E Maguin, E Stanley, EJ Luesink, EJ Luesink, EJ Luesink, F Desiere, F Desiere, G Buist, G Buist, G Ramsay, G Vriend, GM Djordjevic, GM Djordjevic, H Brüssow, H Holo, H Neve, I Biswas, J Bardowski, J Bernhardt, J Green, J Law, J Payne, J Stülke, JB Luchansky, JD Boyce, JW Sanders, JW Sanders, JW Sanders, K Chung, K Leenhouts, K Leenhouts, K Leenhouts, K Schnetz, KI Kodaira, KJ Leenhouts, L Dupont, L Dupont, LJ Beamer, LR Garcia, M Curie, M de Guchte, M de Guchte, M Lieb, M Ptashne, MG Johnsen, MJ Gasson, MJ Weickert, MM Sheehan, MW Lubbers, MW Lubbers, N Goupil-Feuillerat, OP Kuipers, P Hals, PG Ruyter, PGGA Ruyter, PL Madsen, PS Chandry, R Parreira, R Schmid, R Young, R Young, RR Raya, S Challou, S Lucchini, S Lucchini, S Simonen, S Spiro, S Spiro, SA Walker, SB Mclvilc, SG Kim, SM Heller, SM Madsen, SR Swindell, T Sasaki, TM Ramseier, V Vagner, WM Vos, WM Vos, WM Vos, Y Fujita   +110 more
core   +3 more sources