Results 11 to 20 of about 13,886 (146)

Engineered Lactococcus lactis secreting Flt3L and OX40 ligand for in situ vaccination-based cancer immunotherapy

Nature Communications, 2022
In situ vaccination is a promising strategy to convert the immunosuppressive tumor microenvironment into an immunostimulatory one with limited systemic exposure and side effect.
Junmeng Zhu, Yaohua Ke, Qin Liu, Ju Yang, Fangcen Liu, Ruihan Xu, Hang Zhou, Aoxing Chen, Jie Xiao, F. Meng, Lixia Yu, Rutian Li, Jia Wei, Baorui Liu   +13 more
semanticscholar   +1 more source

Extracellular vesicle formation in Lactococcus lactis is stimulated by prophage‐encoded holin–lysin system

Microbial Biotechnology, 2022
Gram‐positive bacterial extracellular membrane vesicles (EVs) have been drawing more attention in recent years. However, mechanistic insights are still lacking on how EVs are released through the cell walls in Gram‐positive bacteria.
Yue Liu, M. Tempelaars, S. Boeren, S. Alexeeva, E. Smid, T. Abee   +5 more
semanticscholar   +1 more source

Immunoregulatory effects of Lactococcus lactis‐derived extracellular vesicles in allergic asthma

Clinical and Translational Allergy, 2022
Background Probiotics have been shown to prevent various allergic diseases by producing extracellular vesicles (EVs). However, the role of EVs in allergic asthma has not yet been completely determined.
Dong-Hyun Lee, H. Park, Hee-Ra Lee, Hyeukjun Sohn, Soyoon Sim, H. Park, Y. Shin, Yoon-Keun Kim, Youngwoo Choi, Hae‐Sim Park   +9 more
semanticscholar   +1 more source

Acoustic Emission Signal of Lactococcus lactis before and after Inhibition with NaN₃ and Infection with Bacteriophage c2 [PDF]

ISRN Microbiology, 2013
The detection of acoustic emission (AE) from Lactococcus lactis, ssp lactis is reported in which emission intensities are used to follow and define metabolic activity during growth in nutrient broths. Optical density (OD) data were also acquired during L.
Debasish Ghosh, John M. Stencel, Clair D. Hicks, Fred Payne, Didem Ozevin   +4 more
openaire   +2 more sources

Expression of Genes Encoding F ₁ -ATPase Results in Uncoupling of Glycolysis from Biomass Production in Lactococcus lactis [PDF]

Applied and Environmental Microbiology, 2002
ABSTRACT We studied how the introduction of an additional ATP-consuming reaction affects the metabolic fluxes in Lactococcus lactis . Genes encoding the hydrolytic part of the F 1 domain of the membrane-bound (F 1 F 0 ) H +
Brian J, Koebmann, Christian, Solem, Martin B, Pedersen, Dan, Nilsson, Peter R, Jensen   +4 more
openaire   +2 more sources

Arginine deiminase originating fromLactococcus lactisssp.lactisAmerican Type Culture Collection (ATCC) 7962 induces G₁-phase cell-cycle arrest and apoptosis in SNU-1 stomach adenocarcinoma cells [PDF]

British Journal of Nutrition, 2009
There are multiple lines of evidence that lactic acid bacteria (LAB) exert cancer-preventive effects. However, the underlying mechanisms are poorly understood. In the present study we found that the cytoplasmic fraction ofLactococcus lactisssp.lactisAmerican Type Culture Collection (ATCC) 7962 exerted the strongest antiproliferative effects (half ...
Jong-Eun, Kim, Seo Young, Kim, Ki Won, Lee, Hyong Joo, Lee   +3 more
openaire   +2 more sources

Diversity Analysis of Dairy and Nondairy Lactococcus lactis Isolates, Using a Novel Multilocus Sequence Analysis Scheme and (GTG) ₅ -PCR Fingerprinting [PDF]

Applied and Environmental Microbiology, 2007
ABSTRACT The diversity of a collection of 102 lactococcus isolates including 91 Lactococcus lactis isolates of dairy and nondairy origin was explored using partial small subunit rRNA gene sequence analysis and limited phenotypic analyses. A subset of 89 strains of L. lactis subsp.
Rademaker, J.L.W., Herbet, H., Starrenburg, M.J.C., Naser, S.M., Gevers, D., Kelly, W.J., Hugenholtz, J., Swings, J., van Hylckama Vlieg, J.E.T.   +8 more
openaire   +3 more sources

Tarkhineh as a new microencapsulation matrix improves the quality and sensory characteristics of probiotic Lactococcus lactis KUMS-T18 enriched potato chips

Scientific Reports, 2021
In the present study, probiotic potato chips containing a newly isolated probiotic Lactococcus lactis KUMS-T18 strain were produced by using a simple spraying method and then enhancing the stability, survival rate, and sensory characteristics of product ...
A. Kiani, Y. Nami, Shahab Hedayati, M. Jaymand, H. Samadian, Babak Haghshenas   +5 more
semanticscholar   +1 more source

GABA-Producing Lactococcus lactis Strains Isolated from Camel’s Milk as Starters for the Production of GABA-Enriched Cheese

Foods, 2021
The multiple health benefits attributed to the bioactive compound γ-aminobutyric acid (GABA) have prompted the food industry to investigate the development of functional GABA-rich foods via the use of GABA-producing microorganisms. This study reports the
B. Redruello, Y. Saidi, L. Sampedro, V. Ladero, B. del Rio, M. Álvarez   +5 more
semanticscholar   +1 more source

Hydrolysis of α_s1‐ and β‐casein‐derived peptides with a broad specificity aminopeptidase and proline specific aminopeptidases from Lactococcus lactis subsp. cremoris AM2 [PDF]

FEBS Letters, 1999
Aminopeptidase hydrolysis of αs1‐ and β‐casein‐derived synthetic peptides containing non‐consecutive and consecutive proline residues was characterised. Aminopeptidase P (Pep P) (EC 3.4.11.9) or post‐proline dipeptidyl aminopeptidase (PPDA) (EC 3.4.14.5) along with lysine‐paranitroanilide hydrolase (KpNA‐H) (EC 3.4.11.1) activities are required in the ...
Bouchier, Paul J., Fitzgerald, Richard J., O'Cuinn, Gerard   +2 more
openaire   +3 more sources