Results 11 to 20 of about 98,587 (340)

Acetylcholinesterase Inhibitory Potential of Various Sesquiterpene Analogues for Alzheimer’s Disease Therapy

Biomolecules, 2021
Alzheimer’s disease (AD) is a gradually growing irreversible illness of the brain that almost affects every fifth person (aged > 80 years) in the world. World Health Organization (WHO) also revealed that the prevalence of this disease will enhance (upto ...
Ashwani Arya, Rubal Chahal, Rekha Rao, Md. Habibur Rahman, Deepak Kaushik, Muhammad Furqan Akhtar, Ammara Saleem, Shaden M. A. Khalifa, Hesham R. El-Seedi, Mohamed Kamel, Ghadeer M. Albadrani, Mohamed M. Abdel-Daim, Vineet Mittal   +12 more
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Contribution of microscopy for understanding the mechanism of action against trypanosomatids [PDF]

, 2018
Transmission electron microscopy (TEM) has proved to be a useful tool to study the ultrastructural alterations and the target organelles of new antitrypanosomatid drugs.
A Martinez-Palomo, A Montalvetti, A Rassi, AB Penissi, AE Eakin, AH Kolien, AJ Solari, AM Sánchez, Ana Yecê das Neves Pinto, C Brack, CF Silva Da, D Gonzalez-Pacanowska, DA Campbell, DA Johnston, DJ Hammond, DV Andrade, E Bontempi, E Lozano, E Lozano, E Lozano, EO Ogbadoiyi, ES Garcia, ES Lozano, F Dos Reis, FR Opperdoes, FR Opperdoes, FR Opperdoes, FS Laranja, H Meyer, H Meyer, J Aldunate, J Lukes, J McKerrow, J Mottram, JA Urbina, JA Urbina, JA Urbina, JA Urbina, JC Engel, JC Linder, JCP Dias, JCP Dias, JD Bergstrom, JD Maya, JF Turrens, JJ Marr, JL Avila, JL Avila, Juliano de Toledo, K Lazardi, K Miranda, K Miranda, KH Lee, L Simpson, LV Muschietti, M Meirelles, M Nieto, MC Elias, MCQB Elias, MR Ariyanayagam, MR Ariyanayagam, NM Sayed El, O Campetella, OS Giordano, OS Giordano, P Barrera, P Webster, PF Pimenta, R Docampo, S Sepúlveda-Boza, SD Brengio, SR Wilkinson, T Souto-Padron, T Souto-Padron, T Souto-Padron, T Souto-Padron, TA Shapiro, TS Tiuman, V Jimenez-Ortiz, V Sülsen, VP Sülsen, VP Sülsen, VV Costantino, W Souza De, W Souza De, W Souza De, W Souza De, W Souza De, W Souza De, Wanderley de Souza, WE Gutteridge   +90 more
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The development of human sera tests for HDL-bound serum PON1 and its lipolactonase activitys⃞

Journal of Lipid Research, 2007
Serum paraoxonase (PON1) is a lipolactonase that associates with HDL-apolipoprotein A-I (HDL-apoA-I) and thereby plays a role in the prevention of atherosclerosis. Current sera tests make use of promiscuous substrates and provide no indications regarding
Leonid Gaidukov, Dan S. Tawfik
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Synthesis of spiroacetals using functionalised titanium carbenoids [PDF]

, 2008
Alkylidenation of lactones with functionalised titanium carbenoid reagents (Schrock carbenes) followed by acid-induced cyclisation of the resulting enol ethers constitutes a new method for the preparation of [4.4], [4.5] and [5.5] spiroacetals (1,6 ...
Aho, Alcaide, Boxer, Brimble, Calver A. Main, Canova, Chang, Cuzzupe, Denmark, Doubsky, D’Annibale, El-Badri, Enders, Evans, Furrow, Godoy, Hartley, Hayes, Horikawa, Inoue, Ireland, Keaton, Krishna, Kumar, Lowe, Lu, Macleod, McKiernan, Mead, Morimoto, Mortimore, Nakashima, Ousset, Paquette, Paterson, Perron, Petasis, Phillips, Richard C. Hartley, Sakaguchi, Shahzad S. Rahman, Takai, Takeda, Tebbe, Tietze, Tsang, Van Orden, Velluci, Vuagnoux-D’Augustin, Wang, Yan, Yang, Zhou   +52 more
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Formation of carboxylic acids during degradation of monosaccharides

Czech Journal of Food Sciences, 2008
The formation of low molecular carboxylic and hydroxycarboxylic acids as well as sugar and deoxysugar acids from monosaccharides (D-glucose, D-fructose, D-arabinose, DL-glyceraldehyde, and 1,3-dihydroxyacetone) was studied in three different model ...
Ondřej Novotný, Karel Cejpek, Jan Velíšek   +2 more
doaj   +1 more source

Synthesis and analysis of stable isotope-labelled N-acyl homoserine lactones [PDF]

, 2016
Aliphatic aldehydes were deuterated at the alpha-position via a base-catalyzed exchange reaction with D2O. These deuterated building blocks were used for the synthesis of labelled analogues of quorum sensing signal molecules belonging to the three major ...
De Kimpe, Norbert, Mangelinckx, Sven, Ruysbergh, Ewout, Stevens, Christian   +3 more
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Xanthium strumarium - a potential cheap resource of plant substances for medicinal use [PDF]

, 2019
Xanthium strumarium L. (Asteraceae) is an annual herb which reproduces solely by seed. So far its centre of origin was considered Central or South America. Recent archeological research revealed that the burs of X.
Ionkova I., Kozuharova E., Spadaro V.
core   +1 more source

Thioether-catalysed tandem synthesis of furans and cyclic ethers or lactones [PDF]

, 2017
Acyclic conjugated ynenediones tethered to an alcohol or carboxylic acid are converted into furanyl-substituted cyclic ethers or lactones in a single step by treatment with the tetrahydrothiophene.
Clark, J. Stephen, Klaus, Verena
core   +1 more source

Synthesis and Cytotoxic Activity of Some 3-Benzyl-5-Arylidenefuran-2(5H)-ones

Molecules, 2007
3-Benzyl-furan-2(5H)-one (2a) and 3-(4-bromobenzyl)-furan-2(5H)-one (2b) were treated with TBDMSOTf and converted into the corresponding tert-butyldimethyl-silylfuran ethers.
Manoel Odorico Moraes, Cláudia Pessoa, Letícia Veras Costa-Lotuf, Daniel Pereira Bezerra, Marcelo Eça Rocha, Célia Regina Alvares Maltha, Luiz Cláudio Barbosa, Róbson Ricardo Teixeira   +7 more
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The Castagnoli–Cushman Reaction

Molecules, 2023
Since the first reports of the reaction of imines and cyclic anhydrides by Castagnoli and Cushman, this procedure has been applied to the synthesis of a variety of lactams, some of them with important synthetic or biological interest.
José Luis Ramiro, Sonia Martínez-Caballero, Ana G. Neo, Jesús Díaz, Carlos F. Marcos   +4 more
doaj   +1 more source