ABSTRACT Neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD), are characterized by the pathological aggregation of specific proteins such as amyloid beta (Aβ) and α‐synuclein, respectively. Early detection of these protein aggregates in biological fluids could facilitate timely diagnosis and therapeutic ...
Alexandra Dybala +4 more
wiley +1 more source
Integrated Analytical Approach to Identify Whey Permeate Powder Caking: Revealing Internal Structure Using X-Ray Micro-Tomography. [PDF]
Szołtysik M +5 more
europepmc +1 more source
1H MR‐based detection of human plasma metabolic alterations in clear cell renal cell carcinoma
Abstract Objectives This study aimed to evaluate the potential of plasma‐based proton magnetic resonance spectroscopy (1H‐MRS) for non‐invasive discrimination between clear cell renal cell carcinoma (ccRCC), benign renal masses (angiomyolipoma and oncocytoma) and healthy controls by identifying disease‐specific metabolic signatures.
Raj Kumar Sharma +6 more
wiley +1 more source
Community based countrywide analysis of lactase persistence related genetic variants and their correlation with digestive symptoms in Libya. [PDF]
Mustafa AM +7 more
europepmc +1 more source
Severe Restriction of Glucose Import Enhances Recombinant Protein Production in Escherichia coli
Graphical Abstract and Lay Summary Producing recombinant proteins in Escherichia coli is often limited by the bacterium's tendency to consume glucose too rapidly. This excessive glucose uptake causes overflow metabolism, leading to the accumulation of acetate, a byproduct that can reduce cellular performance and protein production.
Juan Carlos Fragoso‐Jiménez +5 more
wiley +1 more source
Metabolic pathway analysis reveals hierarchical pentose sugar utilization and metabolic flexibility of <i>Bifidobacterium longum</i>. [PDF]
Friess L +6 more
europepmc +1 more source
Metabolic Fingerprinting of Urine Reveals Metabolite Changes in Women With Breast Cancer
This study uses metabolomics to compare urine, plasma and serum metabolite profiles across breast cancer, benign breast disease, symptomatic and healthy controls. Significant metabolic differences—especially in amino acids—were found between BC and other groups, with moderate correlations across biofluids, suggesting potential for non‐invasive BC ...
Nur Aimi Aliah Zainurin +9 more
wiley +1 more source
Impact of Lactose Phosphate Impurities on Lactose Crystallization: Deionization as Effective Pretreatment. [PDF]
Trespi S, Mazzotti M.
europepmc +1 more source
ABSTRACT Neonatal limb gangrene with auto‐amputation is rare and often idiopathic. Early recognition, prompt referral, and thorough etiologic workup—despite resource limitations—are critical. Wet gangrene requires broad‐spectrum antibiotics, wound care, and timely surgical amputation to preserve growth plates and allow future prosthesis fitting.
Milki Tufa Feyisa +7 more
wiley +1 more source
Network-based allosteric analysis of galectin-7: Key residues dictate functional communication and stability. [PDF]
Pham NTH +8 more
europepmc +1 more source

