Results 101 to 110 of about 7,301 (235)
A virologist’s guide to hide and seek : evasion of innate immunity by primate lentiviruses [PDF]
, 2015 HIV is the cause of a chronic, incurable infection in 37 million people worldwide in 2014. This thesis investigates how the immune system detects HIV and how in turn HIV avoids detection by the immune system.
Bächle, Susanna M
core +1 more source
Advanced Science, Volume 12, Issue 41, November 6, 2025.In superficial second‐degree burn wounds, Gb3 turns on genes related to papillary cells through the FGF2 signaling pathway. This increases the ability of cells to break down fibrin and decreases fibrosis, which ultimately prevents scar formation in burn injuries.
Sujie Xie +13 more
wiley +1 more source
Glucosylceramide synthase inhibitors differentially affect expression of glycosphingolipids [PDF]
, 2017 Glucosylceramide synthase (GCS) catalyzes the first committed step in the biosynthesis of glucosylceramide (GlcCer)-related glycosphingolipids (GSLs). Although inhibitors of GCS, PPMP and PDMP have been widely used to elucidate their biological function ...
Alam, Shahidul +3 more
core
Time and cell-dependent effects of endocytosis inhibitors on the internalization of biomolecule markers and nanomaterials [PDF]
, 2018 Endocytosis is an essential function of cells, with key roles in the internalisation of nutrients, signal molecules and also drugs. Endocytic processes are therefore widely investigated in the context of drug delivery, and inhibitors of endocytic ...
Amaral +56 more
core +4 more sources
Ecology and Evolution, Volume 15, Issue 11, November 2025.Genomic regions potentially associated with resistance against imidacloprid in the Colorado potato beetle were identified here using bulked segregant analysis. Candidate genes were then narrowed down using the functional annotation and expression analysis.
Alitha Edison +3 more
wiley +1 more source
Cholesteryl hemiesters alter lysosome structure and function and induce proinflammatory cytokine production in macrophages [PDF]
, 2017 Rationale: Cholesteryl hemiesters are oxidation products of polyunsaturated fatty acid esters of cholesterol. Their oxo-ester precursors have been identified as important components of the "core aldehydes" of human atheromata and in oxidized lipoproteins
António Jacinto +12 more
core +1 more source
Advanced Science, Volume 12, Issue 38, October 13, 2025.A tumor‐penetrating photooncolytic phage is developed for selectively targeting and delivering photosensitizers to GD2‐positive Neuroblastoma cells. Upon light activation, it precisely induces oncolysis of GD2‐positive cells with no effect on GD2‐negative ones.
Suleman Khan Zadran +25 more
wiley +1 more source
Fundamental Neurochemistry Review: Sphingolipids and Ceramides in Brain Development
Journal of Neurochemistry, Volume 169, Issue 10, October 2025.Ceramides and sphingolipids in brain development and cell compartments. Ceramides and sphingolipids are known to influence multiple steps of brain development, including the formation of the neural tube, neural stem cell polarity and proliferation at the ventricular boundary, neuronal migration—for example, whilst migrating on radial glial processes ...
Kaviya Chinnappa +2 more
wiley +1 more source
Underlying dyslipidemia postpartum in women with a recent GDM pregnancy who develop type 2 diabetes
eLife, 2020 Approximately, 35% of women with Gestational Diabetes (GDM) progress to Type 2 Diabetes (T2D) within 10 years. However, links between GDM and T2D are not well understood. We used a well-characterised GDM prospective cohort of 1035 women following up to 8
Mi Lai +5 more
doaj +1 more source
Fostering collaborative research for rare genetic disease: The example of Niemann-Pick type C disease [PDF]
, 2016 Rare disease represents one of the most significant issues facing the medical community and health care providers worldwide, yet the majority of these disorders never emerge from their obscurity, drawing little attention from the medical community or the
Austin, Christopher P +8 more
core +2 more sources