Results 81 to 90 of about 4,156 (155)

Accumulation of Unusual Gangliosides G_Q3 and G_P3 in Breast Cancer Cells Expressing the G_D3 Synthase

Molecules, 2012
Glycosphingolipids from the ganglio-series are usually classified in four series according to the presence of 0 to 3 sialic acid residues linked to lactosylceramide.
Agata Steenackers, Jorick Vanbeselaere, Aurélie Cazet, Marie Bobowski, Yoann Rombouts, Florent Colomb, Xuefen Le Bourhis, Yann Guérardel, Philippe Delannoy   +8 more
doaj   +1 more source

Effect of membrane lipids on the lactosylceramide molecular species specificity of CMP-N-acetylneuraminate:lactosylceramide sialyltransferase

Journal of Lipid Research, 1993
It has previously been shown that when the molecular species specificity of rat liver Golgi CMP-N-acetylneuraminate:lactosylceramide alpha 2,3-sialyltransferase was determined, using as the substrate lactosylceramide (LacCer) incorporated into liposomes ...
H Kadowaki, MA Grant, LA Williams
doaj   +1 more source

Structure and biosynthetic pathways of the major brain gangliosides [nomenclature is that of Svennerholm [40]].

, 2013
Cer, ceramide; LacCer, lactosylceramide. GM1, GD1a, GD1b and GT1b comprise up to 97% of all gangliosides in the human central nervous system (boxed area).
Katarina Vajn (464671), Marija Heffer (464675), Barbara Viljetić (464672), Ivan Večeslav Degmečić (464673), Ronald L. Schnaar (464674)   +4 more
core   +1 more source

Enzymatic Sulfation of Glycosphingolipids in Rat Parotid Salivary Glands

, 1983
The results of this study demonstrate that sulfatoglycosphingolipids of rat parotid salivary glands consist of galactosylceramide and lactosylceramide sulfates.
Y.H. Liau, A. Slomiany, B.L. Slomiany, E. Zdebska   +3 more
core   +1 more source

Regulation of EMT-MET and chemoresistance by the Lc3Cer-synthase B3GNT5

BMC Cancer
Background Glycosphingolipids (GSL) are essential components of the plasma membrane where they are known to play key structural and functional roles and are known to influence molecular processes involved in cancer malignancy, including multi-drug ...
Laura E. Clark, Katherine Hylton Rorie, Amanda J. G. Dickinson, Santiago Lima   +3 more
doaj   +1 more source

Image_1_α-Lactosylceramide Protects Against iNKT-Mediated Murine Airway Hyperreactivity and Liver Injury Through Competitive Inhibition of Cd1d Binding.TIF

, 2019
Invariant natural killer T (iNKT) cells, which are activated by T cell receptor (TCR)-dependent recognition of lipid-based antigens presented by the CD1d molecule, have been shown to participate in the pathogenesis of many diseases, including asthma and ...
Christina Li-Ping Thio (8057234), Hsien-Neng Kao (8057237), Hsiao-Wu Hsieh (1308807), Alan Chuan-Ying Lai (1395826), Yun-Chiann Han (1395820), Po-Yu Chi (8057231), Jacquelyn Gervay-Hague (1308804), Ya-Jen Chang (547293)   +7 more
core   +1 more source

β-glycosphingolipids ameliorated non-alcoholic steatohepatitis in the Psammomys obesus model

Journal of Inflammation Research, 2014
Ehud Zigmond,1,* Oshrat Tayer-Shifman,1,* Gadi Lalazar,1 Ami Ben Ya'acov,1 Sarah Weksler-Zangen,2 David Shasha,1 Miriam Sklair-Levy,3 Lidya Zolotarov,1 Zvi Shalev,1 Rony Kalman,2 Ehud Ziv,2 Itamar Raz,2 Yaron Ilan1 1Liver Unit, 2Diabetes Unit ...
Zigmond E, Tayer-Shifman O, Lalazar G, Ben Ya'acov A, Weksler-Zangen S, Shasha D, Sklair-Levy M, Zolotarov L, Shalev Z, Kalman R, Ziv E, Raz I, Ilan Y   +12 more
doaj  

Role of FAM57B2 and Lactosylceramide in Chondrogenesis

, 2018
Chondrogenesis is critical for the healing of fractured bones. After an initial inflammation stage, a "soft callus" composed of chondrocytes bridges the injury site, to be later mineralized and substituted by bone.
Antonyan, Lilit
core  

Absence of BODIPY-glycolipids from TWEEs.

, 2013
Sections of mucosal explants cultured for 1 h in the presence of BODIPY-lactosylceramide (Bod-laccer), BODIPY-GM1 (Bod-GM1), or BODIPY-GM1 and CTB (Bod-GM1+CTB).
E. Michael Danielsen (467141), Gert H. Hansen (467142)   +1 more
core   +1 more source

Lipidomic characterization of bile and serum reveals an altered lipid landscape in end-stage primary sclerosing cholangitis

Scientific Reports
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammation and fibrosis of bile ducts, yet its metabolic underpinnings remain poorly defined.
Seul Kee Byeon, Saniha Sabu, Pamela S. Tietz-Bogert, Jagadheshwar Balan, Steven P. O’Hara, Nicholas F. LaRusso, Akhilesh Pandey   +6 more
doaj   +1 more source