Results 41 to 50 of about 382,242 (307)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Algunas consideraciones acerca del Conde Casio

Studia Historica. Historia Medieval, 2011
El conde Casio, epónimo de los Banu Qasi, apenas fue tratado por los cronistas árabes o latinos si no fue para resaltar la figura de sus descendientes, los Banu Qasi.
Jesús LORENZO JIMÉNEZ
doaj  

On-sky demonstration of reinforcement learning for adaptive optics control

Astronomy & Astrophysics
Context. Reinforcement-learning- (RL-) based algorithms have recently emerged as a promising approach for adaptive optics (AO) control. In simulations and laboratory experiments, they have demonstrated robustness to real-world effects such as photon and ...
Nousiainen J., Chambouleyron V., Neichel B., Cetre S., Sauvage J.-F., Alagao A., Kasper M., Dray J., Fétick R., Engler B.   +9 more
doaj   +1 more source

LAM concentration in NTM culture solutions determined by LAM-ELISA.

, 2019
LAM concentration in NTM culture solutions determined by LAM-ELISA.
Lawrence Raymond (6584972), Tetsuya Oda (6584981), Evelyn Reside (6584978), Ryuta Ito (6584984), Elizabeth Cadena (6584975), Masanori Kawasaki (274320), Carmenchu Echiverri (6584969), Yongge Liu (3798460), Ryo Higashiyama (3343958), Maria Tarcela Gler (197320), Kiyonori Katsuragi (3343937)   +10 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Lam lam o lam (6/4 e)

, 2011
Laulun sanat: Lam, lam o lam, Så undersan, Förtryckt, försökt; Dock likväl älskadt högt! Mitt hjerta är ej mitt, Men ditt: Din lön, Guds Lam, För hån och skam, För sårens flod Och för ditt kors och ...

core   +1 more source

New morpho-kinematic classification: The two-dimensional spatial distribution of stellar specific angular momentum in late-type galaxies

Astronomy & Astrophysics
Aims. The two-dimensional spatial distribution of stellar specific angular momentum (sAM) within galaxies has never been analysed. We seek to identify the morpho-kinematics of this property and its correlation with the total stellar sAM (j★) and the ...
Pacheco-Arias Juan Manuel, Amram Philippe, Epinat Benoît, Mercier Wilfried   +3 more
doaj   +1 more source

Induced Pluripotent Stem Cells-Derived Mesenchymal Stem Cells Attenuate Cigarette Smoke-Induced Cardiac Remodeling and Dysfunction

Frontiers in Pharmacology, 2017
The strong relationship between cigarette smoking and cardiovascular disease (CVD) has been well-documented, but the mechanisms by which smoking increases CVD risk appear to be multifactorial and incompletely understood. Mesenchymal stem cells (MSCs) are
Yingmin Liang, Yingmin Liang, Xiang Li, Xiang Li, Yuelin Zhang, Sze Chun Yeung, Sze Chun Yeung, Zhe Zhen, Mary S. M. Ip, Mary S. M. Ip, Mary S. M. Ip, Hung Fat Tse, Qizhou Lian, Qizhou Lian, Qizhou Lian, Qizhou Lian, Judith C. W. Mak, Judith C. W. Mak, Judith C. W. Mak, Judith C. W. Mak   +19 more
doaj   +1 more source

Su1308 HERE A LAMS. THERE A LAMS. EVERYWHERE A LAMS [PDF]

Gastrointestinal Endoscopy, 2020
Jun-Ho Choi, Richard A. Kozarek, Michael C. Larsen, Andrew S. Ross, Joanna K. Law, Rajesh Krishnamoorthi, Shayan S. Irani   +6 more
openaire   +1 more source