Results 51 to 60 of about 382,242 (307)

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Nebular_AGN: A CIGALE module for fitting active galactic nucleus emission lines

open access: yesAstronomy & Astrophysics
Aims. The increasing discovery of high-redshift active galactic nuclei (AGNs) in recent years imposes more stringent requirements on spectral analysis tools for deriving the properties of AGNs and their host galaxies from emission-line diagnostics.
Zhang Hao   +5 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

An in-depth Analysis of Undergraduates’ Study Skills: A Study at Nong Lam University

open access: yesVietnam Journal of Education, 2022
Study skills are critical to students’ achievement. The objective of this study is to assess the study skills of undergraduates. The Inventory of College Level Study Skills developed by Dennis H.
Viet Van Vo   +2 more
doaj  

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Language Learning Strategies Employed by Non-English Majors at Nong Lam University, Vietnam

open access: yesVietnam Journal of Education, 2023
Learning strategies have a strong effect on students’ success in foreign language learning. In fact, they are considered tools for active and self-directed engagement, which is vital for developing communicative competence.
Van Viet Vo   +2 more
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Finding haloes in the Lyman-α forest

open access: yesAstronomy & Astrophysics
It has been demonstrated that one can track down galaxies in absorption hidden in the Lyman-α forest through the use of ‘strong, blended Lyman-α’ (or SBLA) absorption.
Muñoz Santos Duarte   +5 more
doaj   +1 more source

miR-200c Prevents TGF-β1-Induced Epithelial-to-Mesenchymal Transition and Fibrogenesis in Mesothelial Cells by Targeting ZEB2 and Notch1

open access: yesMolecular Therapy: Nucleic Acids, 2019
Peritoneal fibrosis and loss of transport function is a common complication contributing to adverse outcomes in patients on long-term peritoneal dialysis (PD).
Jessica Y.S. Chu   +6 more
doaj   +1 more source

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