Results 71 to 80 of about 382,242 (307)
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Tiffany Lam (Class of 2021) was interviewed by Sarah Khoja via the Zoom internet-based video conferencing software on June 21, 2022. Ms. Lam was born and raised in Plano, Texas.
Lam, Tiffany; Khoja, Sarah
core
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
The Four Onions : Amy Ching-Yan Lam
"These poems started with food. I was writing down what I talked about most, and I talked a lot about the things I eat and don’t eat. For example, beef jerky vs. eggs.
Lam, Amy Ching-Yan
core +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
This study aims to analyze the current state of coffee production and the factors influencing coffee farmers’ decisions in selecting purchasing partners in the Central Highlands of Vietnam.
Thi Thu Hoa Ha +2 more
doaj +1 more source
We present the analysis of the multi-planetary system Kepler-117, which is part of our program of observations of Kepler planets. This system is composed of a ~ 30 MEarth planet in a ~ 19 days orbit and a ~ 2 MJ planet orbiting in ~ 51 days.
Bruno G. +11 more
doaj +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
the appearance of the lumen-apposing metal stent (LAMS) has meant an authentic revolution. To date, the results are promising but it is necessary to note the technical incidents and LAMS-related complications.an EUS-transmural guided drainage using a HotAXIOS was planned for a 36-year-old man with oral intolerance due to a voluminous walled-off ...
Curieses Luengo, Maria +3 more
openaire +5 more sources
TBSA Based LAM Estimation of 29 Urine Samples (TBSSMC -, D-Arabinose/LAM positive).
TBSA Based LAM Estimation of 29 Urine Samples (TBSSMC -, D-Arabinose/LAM positive).
Prithwiraj De (833532) +5 more
core +1 more source

