Results 221 to 230 of about 52,713 (325)

Mitochondrial stress disassembles nuclear architecture through proteolytic activation of PKCδ and Lamin B1 phosphorylation in neuronal cells: implications for pathogenesis of age-related neurodegenerative diseases. [PDF]

Front Cell Neurosci
Charli A, Chang YT, Luo J, Palanisamy B, Malovic E, Riaz Z, Miller C, Samidurai M, Zenitsky G, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG.   +12 more
europepmc   +1 more source

Lovastatin-induced apoptosis in thyroid cells: involvement of cytochrome c and lamin B [PDF]

, 2001
Tiziana Di Matola, F. D’Ascoli, Cristina Luongo, Maurizio Bifulco, Giacomo Rossi, Gianfranco Fenzi, Mario Vitale   +6 more
openalex   +1 more source

Ultrastructure of the Endoplasmic Reticulum in Eukaryotic Microalgae

Journal of Eukaryotic Microbiology, Volume 72, Issue 5, September/October 2025.
ABSTRACT The endoplasmic reticulum (ER) is a large and highly dynamic component of the eukaryotic endomembrane system. In eukaryotic microalgae, it plays six distinct roles: (1) It envelopes the chromatin to form the nucleus. (2) It forms cisternae in the cytoplasm, some of which scaffold the synthesis of proteins destined for incorporation into ...
Ursula Goodenough, Robyn Roth
wiley   +1 more source

Development of translational read-through-inducing drugs as novel therapeutic options for patients with Fanconi anemia. [PDF]

Cell Death Discov
Hristodor AM, Cappelli E, Baldisseri E, Valli R, Montalbano G, Micheloni G, Porta G, Frattini A, Ravera S, Fioredda F, Lippi G, Dufour C, Cipolli M, Bezzerri V.   +13 more
europepmc   +1 more source

Lamin A/C gene: sex-determined expression of mutations in Dunnigan-type familial partial lipodystrophy and absence of coding mutations in congenital and acquired generalized lipoatrophy.

, 2000
Corinne Vigouroux, Jocelyne Magré, Marie‐Christine Vantyghem, Charlotte Bourut, Olivier Lascols, Sue Shackleton, David J. Lloyd, Bruno Guerci, Giuseppa Padova, P. Valensi, André Grimaldi, R. Piquemal, Philippe Touraine, Richard C. Trembath, Jacqueline Capeau   +14 more
openalex   +1 more source

Both emerin and lamin C depend on lamin A for localization at the nuclear envelope [PDF]

, 2001
O. Anthony Vaughan, Mauricio Alvarez-Reyes, Joanna M. Bridger, Jos L. V. Broers, Frans C.�S. Ramaekers, Manfred Wehnert, Glen E. Morris, William G. F. Whitfield, Christopher J. Hutchison   +8 more
openalex   +1 more source

RONIN/HCF1‐TFEB Axis Protects Against D‐Galactose‐Induced Cochlear Hair Cell Senescence Through Autophagy Activation

Advanced Science, Volume 12, Issue 29, August 7, 2025.
D‐galactose (D‐gal) induced inner ear hair cell senescence by inhibiting TFEB transcription. RONIN/HCF1 promotes TFEB transcription to prevent cochlear HCs from D‐gal‐induced senescence through autophagy activation. Abstract Age‐related hearing loss is characterized by senescent inner ear hair cells (HCs) and reduced autophagy.
Yongjie Wei, Yuhua Zhang, Wei Cao, Nan Cheng, Yun Xiao, Yongjun Zhu, Yan Xu, Lei Zhang, Lingna Guo, Jun Song, Su‐hua Sha, Buwei Shao, Fang Ma, Jingwen Yang, Zheng Ying, Zuhong He, Renjie Chai, Qiaojun Fang, Jianming Yang   +18 more
wiley   +1 more source

The upregulation of lamin A/C as a compensatory mechanism during tight junction disruption in renal tubular cells mediated by calcium oxalate crystals

Current Research in Toxicology
Calcium oxalate monohydrate (COM), the most important crystal causing kidney stone disease, upregulates lamin A/C but downregulates zonula occludens-1 (ZO-1) in renal tubular cells.
Sudarat Hadpech, Paleerath Peerapen, Visith Thongboonkerd   +2 more
doaj  

Ginsenoside Rg3 exerts anticancer effects in lung cancer through metabolite Histon H3. [PDF]

Am J Transl Res
Xiao H, Zhang Y, Zhang B, Wu J, Li X.
europepmc   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, Volume 12, Issue 29, August 7, 2025.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source