Results 231 to 240 of about 52,713 (325)

Chromatin heterogeneity modulates nuclear condensate dynamics and phase behavior. [PDF]

Nat Commun
Xia J, Zhao JZ, Strom AR, Brangwynne CP.
europepmc   +1 more source

Involvement of the Lamin Rod Domain in Heterotypic Lamin Interactions Important for Nuclear Organization [PDF]

, 2001
Eric C. Schirmer, Tinglu Guan, Larry Gerace   +2 more
openalex   +1 more source

LIMK1 as a Novel Kinase of β‐Catenin Promotes Esophageal Cancer Metastasis by Cooperating With CDK5

Advanced Science, Volume 12, Issue 29, August 7, 2025.
Li et al. innovatively map the kinase‐substrate network in esophageal cancer metastasis. Their study demonstrates that LIM domain kinase 1 (LIMK1) and Cyclin‐dependent kinase 5 (CDK5) synergistically increase the phosphorylation of β‐catenin, thereby activating the Wnt/β‐catenin signaling pathway to promote esophageal cancer metastasis.
Shu‐Jun Li, Zhuo‐Ran Liang, Zhi‐Chao Liu, Xue‐Ping Luo, Jun‐Yi Li, Xiao‐Mei Yu, Xuan‐Zhang Huang, Yan He, Tao‐Yang Xu, Jiao‐Jiao Xu, Shao‐Cong Peng, Yu‐Xiang Song, Yan He, Xiao‐Wan Zhuang, Can‐Can Zheng, Fan Zhang, Alfred King‐Yin Lam, Wei Dai, Ming‐Liang He, Bo Liu, Qi Zhao, Guo‐Liang Lu, Jin‐Bao Liu, Zhen‐Ning Wang, Zhi‐Gang Li, Ze‐Xian Liu, Wen‐Wen Xu, Bin Li   +27 more
wiley   +1 more source

Retrograde rearrangement of mitochondria correlates with nuclear deformation and genotoxic damage. [PDF]

iScience
Jobst M, Crudo F, Marko D, Bileck A, Meier-Menches SM, Gerner C, Del Favero G.   +6 more
europepmc   +1 more source

Mutational and Haplotype Analyses of Families with Familial Partial Lipodystrophy (Dunnigan Variety) Reveal Recurrent Missense Mutations in the Globular C-Terminal Domain of Lamin A/C

, 2000
Rebecca A. Speckman, Abhimanyu Garg, Fenghe Du, Lynda Bennett, Rose Veile, Elif Arioǧlu, Simeon I. Taylor, Michael Lovett, A. Bowcock   +8 more
openalex   +1 more source

The nuclear envelope and nuclear pore complexes in neurodegenerative diseases. [PDF]

Front Cell Dev Biol
Wu T, Xu H, Cheng L, Wu R, Guo F, Chen X.   +5 more
europepmc   +1 more source

Electron microscopic findings predict clinical outcomes in patients with non‐ischaemic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 4, Page 2441-2449, August 2025.
Abstract Aims Electron microscopy reveals microstructural alterations in cardiomyocyte nuclei and myofilaments in non‐ischaemic cardiomyopathy (NICM), particularly in dilated cardiomyopathy (DCM). Nevertheless, the correlation between such observations and clinical outcomes, including prognosis and left ventricular reverse remodelling (LVRR), remains ...
Rie Higuchi, Shozo Konishi, Tomohito Ohtani, Fusako Sera, Misato Chimura, Machiko Kanzaki, Themistoklis Katsimichas, Masahiro Seo, Tetsuya Watanabe, Takahiro Okumura, Toyoaki Murohara, Hiroyuki Takahama, Atsushi Okada, Chisato Izumi, Masaru Hatano, Issei Komuro, Yoshihiko Ikeda, Yoshihiro Asano, Hatsue Ishibashi‐Ueda, Yasushi Sakata   +19 more
wiley   +1 more source

Lamins and Apoptosis [PDF]

, 2001
Brian Burke
openalex   +1 more source

Discovering new hub genes of dilated cardiomyopathy

ESC Heart Failure, Volume 12, Issue 4, Page 2487-2498, August 2025.
Abstract Aims Dilated cardiomyopathy (DCM) has a poor prognosis and exhibits a complex and diverse aetiology and genetic profile. The genes responsible for the pathogenesis of DCM have not been fully identified. The present study aimed to explore new hub genes of DCM by mining the human DCM databases and further by experimental validation.
Jun‐Yan Zhu, Yu Han, Jing‐Yu Yang, De‐Ping Wang, Li‐Juan Gao, Teng Sun, Yan‐Lin Feng, Zhong‐Mei He, Bin Zhou, Ji‐Min Cao   +9 more
wiley   +1 more source

Autophagy is an upstream mediator of chromatin dynamics in normal and autoimmune germinal center B cells. [PDF]

J Clin Invest
Sallan MC, Filipsky F, Shi CH, Pontarini E, Terranova-Barberio M, Beattie G, Clear A, Bombardieri M, Yip KY, Calado DP, Cragg MS, James S, Carter M, Okosun J, Gribben JG, Klymenko T, Braun A.   +16 more
europepmc   +1 more source