Results 261 to 270 of about 52,713 (325)

Primary cilia prevent activation of the cGAS-STING pathway during mouse decidualization. [PDF]

open access: yesCommun Biol
Li B   +7 more
europepmc   +1 more source

New Click on the Block: Photocaged Hydroxylamine, an Addition to the Light‐Activatable Bioorthogonal Toolbox

open access: yesChemistry – A European Journal, Volume 31, Issue 42, July 25, 2025.
The retro‐Cope bioorthogonal reactivity of hydroxylamines was disabled transiently with a coumarin photolabile protecting group, which could be recovered upon removal of the protecting group by a short, 400 nm light illumination. Light‐controlled recovery of reactivity was demonstrated in bioorthogonal fluorescent labeling schemes of intracellular ...
Krisztina Németh   +5 more
wiley   +1 more source

Aging and Altered Gravity: A Cellular Perspective

open access: yesThe FASEB Journal, Volume 39, Issue 13, 15 July 2025.
We propose that, unlike biological aging, where Primary hallmarks initiate damage, spaceflight may trigger a feedback loop between Antagonistic and Integrative hallmarks, driving accelerated aging. Returning to 1 g restores proper signaling and breaks the cycle.
Sharon van Rijthoven   +1 more
wiley   +1 more source

Vasopressin‐Sensitive Aqp2 Regulation Mediated by the TAZ‐NR4A1 Axis in Renal Collecting Duct Cells

open access: yesThe FASEB Journal, Volume 39, Issue 13, 15 July 2025.
The TAZ‐NR4A1 axis was identified as a critical regulator of vasopressin‐induced AQP2 expression, essential for water homeostasis. Conditional TAZ‐knockout mice showed polyuria and a significant decrease in AQP2 expression in collecting ducts. In mpkCCDc11 cells, TAZ knockdown significantly impaired vasopressin‐mediated AQP2 expression independently of
Hong Seok Choi   +6 more
wiley   +1 more source

Involvement of NRF2 and AMPK signaling in aging and progeria: a digest. [PDF]

open access: yesRedox Biol
Petsouki E   +4 more
europepmc   +1 more source

A role for nuclear lamins in nuclear envelope assembly

open access: bronze, 2001
Reynold I. Lopez‐Soler   +4 more
openalex   +1 more source

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