Results 81 to 90 of about 8,868,086 (239)

Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism

Genome Biology
Background B-type lamins are critical nuclear envelope proteins that interact with the three-dimensional genomic architecture. However, identifying the direct roles of B-lamins on dynamic genome organization has been challenging as their joint depletion ...
Emily M. Pujadas Liwag, Xiaolong Wei, Nicolas Acosta, Lucas M. Carter, Jiekun Yang, Luay M. Almassalha, Surbhi Jain, Ali Daneshkhah, Suhas S. P. Rao, Fidan Seker-Polat, Kyle L. MacQuarrie, Joe Ibarra, Vasundhara Agrawal, Erez Lieberman Aiden, Masato T. Kanemaki, Vadim Backman, Mazhar Adli   +16 more
doaj   +1 more source

H3K9me2 orchestrates inheritance of spatial positioning of peripheral heterochromatin through mitosis

eLife, 2019
Cell-type-specific 3D organization of the genome is unrecognizable during mitosis. It remains unclear how essential positional information is transmitted through cell division such that a daughter cell recapitulates the spatial genome organization of the
Andrey Poleshko, Cheryl L Smith, Son C Nguyen, Priya Sivaramakrishnan, Karen G Wong, John Isaac Murray, Melike Lakadamyali, Eric F Joyce, Rajan Jain, Jonathan A Epstein   +9 more
doaj   +1 more source

A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction [PDF]

, 2008
Background: The skeletal neuromuscular junction is a useful model for elucidating mechanisms that regulate synaptogenesis. Developmentally important intercellular interactions at the neuromuscular junction are mediated by the synaptic portion of a basal ...
Fox Michael A, Ho Matthew SP, Fox, Michael, Sanes Joshua R, Sanes, Joshua R, Ho, Matthew S. P., Smyth, Neil, Sanes, Joshua, Smyth Neil, Fox, Michael A., Sanes, Joshua R., Ho, Matthew S.P., Ho, Matthew SP   +12 more
core   +1 more source

Structural Power Composites Based on High Mass Loading Zn‐Ion Hybrid Supercapacitors with Metal Mesh Current Collectors and Aramid Nanofiber/Glass Fiber Composite Electrolytes

Advanced Functional Materials, EarlyView.
A multifunctional structural power composite is developed by integrating high‐mass‐loading Zn‐ion hybrid supercapacitors with metal mesh current collectors and aramid nanofiber‐based composite electrolytes, enabling simultaneous load‐bearing capability and enhanced areal energy storage.
Yuseung Choi, Gilyong Shin, Hoyeon Lee, Eun Jae Nam, Byeong Jun So, Sungryul Yun, Fu‐Kuo Chang, Jei Gyeong Jeon, Tae June Kang   +8 more
wiley   +1 more source

The Cartridge: A Canonical Neural Circuit Abstraction of the Lamina Neuropil - Construction and Composition Rules [PDF]

, 2014
The Lamina is a neuropil that resides in the optic lobe of the early visual system of the fruit fly. Its neural circuit consists of some 700~800 cartridges.
Zhou, Yiyin, Lazar, Aurel A., Ukani, Nikul H.   +2 more
core   +1 more source

Interaction‐Driven Assembly Pathways in Heterogeneous Active Microrobotic Systems

Advanced Functional Materials, EarlyView.
Peanut‐ and cube‐shaped light‐powered microrobots exhibit distinct magnetic and photocatalytic responses that determine their heterogeneous self‐assembly. In the dark, magnetic dipole interactions drive colloidal copolymerization with cubes acting as nucleation centers, whereas under light irradiation, phoretic interactions compete with magnetic ...
Domenico Calabrò, Roshan Velluvakandy, Martin Pumera, Francesco Priolo, Salvo Mirabella, Mario Urso   +5 more
wiley   +1 more source

Nuclear envelope and chromatin choreography direct cellular differentiation

Nucleus
The nuclear envelope plays an indispensable role in the spatiotemporal organization of chromatin and transcriptional regulation during the intricate process of cell differentiation.
Anjitha Nair, Jayati Khanna, Jashan Kler, Rohith Ragesh, Kundan Sengupta   +4 more
doaj   +1 more source

Genome-wide Anaplasma phagocytophilum AnkA-DNA interactions are enriched in intergenic regions and gene promoters and correlate with infection-induced differential gene expression.

Frontiers in Cellular and Infection Microbiology, 2016
Anaplasma phagocytophilum, an obligate intracellular prokaryote, infects neutrophils and alters cardinal functions via reprogrammed transcription. Large contiguous regions of neutrophil chromosomes are differentially expressed during infection.
J Stephen Dumler, Sara H. Sinclair, Valeria Pappas-Brown, Amol Shetty   +3 more
doaj   +1 more source

Fiber‐reinforced Liquid Metal Composites With Automated Circuit Fabrication for Structurally‐Integrated Power Transfer

Advanced Functional Materials, EarlyView.
Fiber‐reinforced liquid metal composites (FibRe LMCs) are introduced that combine GPa‐scale structural performance with digitally programmable electrical conductivity. Through automated CNC activation, conductive pathways and wireless power transfer circuits are fabricated directly within load‐bearing composites, enabling structurally integrated ...
John Joyce, Charles K. Van Horn, Nathaniel J. Valentin, Angelica Phan, Michael D. Bartlett, Edward J. Barron III   +5 more
wiley   +1 more source

Physiological and pathological ageing affects chromatin dynamics, structure and function at the nuclear edge

Frontiers in Genetics, 2016
Lamins are intermediate filaments that form a complex meshwork at the inner nuclear membrane. Mammalian cells express two types of Lamins, Lamins A/C and Lamins B, encoded by three different genes, LMNA, LMNB1 and LMNB2.
Jérôme D. Robin, Frederique Magdinier
doaj   +1 more source