Results 1 to 10 of about 217,252 (285)

Cryo-EM reveals molecular mechanisms underlying the inhibitory effect of netrin-4 on laminin matrix formation

open access: yesNature Communications
Netrin-4 is a tumor suppressor that interferes with formation of the laminin lattice. We employed cryo-electron microscopy to determine a structure of the protein complex consisting of the N-terminal fragments from netrin-4 and laminin γ1.
Arkadiusz W. Kulczyk   +2 more
doaj   +1 more source

Laminin 332 processing impacts cellular behavior

open access: yesCell Adhesion & Migration, 2013
Laminin 332, composed of the α3, β3 and γ2 chains, is an epithelial-basement membrane specific laminin variant. Its main role in normal tissues is the maintenance of epithelial-mesenchymal cohesion in tissues exposed to external forces, including skin ...
P. Rousselle, K. Beck
semanticscholar   +1 more source

A Family of Laminin α2 Chain-Deficient Mouse Mutants: Advancing the Research on LAMA2-CMD

open access: yesFrontiers in Molecular Neuroscience, 2020
The research on laminin α2 chain-deficient congenital muscular dystrophy (LAMA2-CMD) advanced rapidly in the last few decades, largely due to availability of good mouse models for the disease and a strong interest in preclinical studies from scientists ...
Kinga I. Gawlik, Madeleine Durbeej
doaj   +1 more source

Myelination: all about Rac n roll. [PDF]

open access: yes, 2007
During the development of the peripheral nervous system, Schwann cells select individual axons from a nerve bundle and establish a one-to-one relationship through a process termed radial sorting. Recent findings identify the Rho family GTPase Rac1 as the
Chan, Jonah
core   +2 more sources

The effect of marketing strategies on firm performance: a study of furniture manufacturing SMEs in Johor Malaysia [PDF]

open access: yes, 2017
Marketing strategies are critical to improve the performance of any small and medium-sized business in the world. The purpose of this study is to investigate the importance of marketing strategies for small and medium-sized enterprises in Johor, Malaysia,
Akbar, Fazal
core  

Close relation of arterial ICC-like cells to the contractile phenotype of vascular smooth muscle cell [PDF]

open access: yes, 2007
This work aimed to establish the lineage of cells similar to the interstitial cells of Cajal (ICC), the arterial ICC-like (AIL) cells, which have recently been described in resistance arteries, and to study their location in the artery wall.
Bolton, TB   +5 more
core   +3 more sources

Immobilization of Cell-Adhesive Laminin Peptides in Degradable PEGDA Hydrogels Influences Endothelial Cell Tubulogenesis

open access: yesBioResearch Open Access, 2013
Attachment, spreading, and organization of endothelial cells into tubule networks are mediated by interactions between cells in the extracellular microenvironment.
Saniya Ali   +4 more
semanticscholar   +1 more source

IMMUNOMORPHOLOGICAL FEATURES OF IDIOPATHIC EPIRETINAL MEMBRANES COMPLICATED BY LAMELLAR MACULAR HOLE

open access: yesOftalʹmologiâ, 2017
Objective: Comparative morphological characteristic and evaluation of cytokine profile of idiopathic epiretinal membrane (ERM), complicated lamellar macular hole.
U. R. Altynbaev, A. I. Lebedeva
doaj   +1 more source

Effects of Trans-Cinnamaldehyde on Reperfused Ischemic Skeletal Muscle and the Relationship to Laminin

open access: yesJournal of Investigative Surgery, 2021
Purpose Ischemia-reperfusion (I-R) injury is a serious problem caused by vascular trauma, tourniquet use and/or compartment syndrome. Studies have reported that skeletal muscle function is impaired due to the lower extremity I-R injury.
Esra Pekoglu   +6 more
doaj   +1 more source

Laminin-211 in skeletal muscle function

open access: yesCell Adhesion & Migration, 2013
A chain is no stronger than its weakest link is an old idiom that holds true for muscle biology. As the name implies, skeletal muscle’s main function is to move the bones. However, for a muscle to transmit force and withstand the stress that contractions
J. Holmberg, M. Durbeej
semanticscholar   +1 more source

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