Results 151 to 160 of about 18,044 (328)

Dendranthema oreastrum (Hance) Y.Ling Attenuates Oxidative Stress and Airway Inflammation in a Murine Model of Lipopolysaccharide‐Induced Acute Lung Injury

Environmental Toxicology, EarlyView.
ABSTRACT We examined the antioxidant and anti‐inflammatory effects of the methanolic extract of Dendranthema oreastrum (Hance) Y.Ling, commonly known as “Gu‐Jeol‐Cho” in Korea and widely found across East Asia, using an LPS‐induced acute lung injury (ALI) mouse model and TNF‐α‐stimulated NCI‐H292 cells.
Ji‐Hye Ha, Ba‐Wool Lee, Da‐Hye Yi, Seong‐Hun Jeong, Ju‐Hong Kim, Hyun‐Jae Jang, Ju Hwan Jeong, Ji‐Young Park, Hyung Jae Jeong, Hyung‐Jun Kwon, Young‐Bae Ryu, In‐Chul Lee   +11 more
wiley   +1 more source

CRISPR/Cas9‐edited tumor‐associated immune cells in cancer immunotherapy

VIEW, EarlyView.
Abstract Immuno‐oncology represents an emerging field that has significantly transformed tumor therapeutics, with immune cells serving as the cellular foundations of cancer immunotherapy. Due to its high efficiency and sensitivity, CRISPR/Cas9 genome editing is a highly promising technique for precise and rapid gene modification.
Yuhui Ma, Junxin Chen, Yuan Du, Zhihao Cao, Weizhi Ji, Yuyu Niu, Zebin Yang   +6 more
wiley   +1 more source

Ethnic Polarization and Ownership Decision in Cross‐Border Acquisitions: The Case of Emerging Market Multinational Enterprises

British Journal of Management, EarlyView.
Abstract Ethnic issues have been creating complex sociopolitical realities and grand challenges for economic activities in many countries, yet much less is known about their micro‐level effects on international business. This study explores the impact of ethnic polarization in target countries on equity ownership in cross‐border acquisitions (CBAs) by ...
Jianhong Zhang, Jiangang Jiang
wiley   +1 more source

A complex containing p34cdc2 and cyclin B phosphorylates the nuclear lamin and disassembles nuclei of clam oocytes in vitro. [PDF]

, 1991
G. Dessev, C Iovcheva-Dessev, James R. Bischoff, David Beach, Robert D. Goldman   +4 more
openalex   +1 more source

Transversals to laminations [PDF]

Pacific Journal of Mathematics, 1982
openaire   +4 more sources

Nuclear Import Defects Drive Cell Cycle Dysregulation in Neurodegeneration

Aging Cell, EarlyView.
Overview of Dysregulated Cell Cycle Mechanisms in Neuronal Cells. A nuclear import block drives cell cycle re‐entry from G0, culminating in cell cycle arrest at G1/S. This cell cycle arrest is associated with activation of CKIs from the INK locus (p15, p16, p18, p19) and Cip/Kip (p21, p27) which act on specific CDK/Cyclin complexes.
Jonathan Plessis‐Belair, Taylor Russo, Markus Riessland, Roger B. Sher   +3 more
wiley   +1 more source

Mitogen‐activated protein kinases phosphorylate nuclear lamins and display sequence specificity overlapping that of mitotic protein kinase p34^cdc2 [PDF]

, 1992
Marcus E. Peter, Jasbinder S. Sanghera, Steven Pelech, Erich A. Nigg   +3 more
openalex   +1 more source

DLK/JNK3 Upregulation Aggravates Hair Cell Senescence in Mice Cochleae via Excessive Autophagy

Aging Cell, EarlyView.
In normal physiological processes, autophagy acts as a protective factor against aging stress. With the stress increase, the DLK/JNK3 pathway is activated and autophagy is continuously upregulated. In our study, excessive autophagy leads to hair cell senescence, which reveals that excessive autophagy can play a harmful role in senescence under certain ...
Rui Ding, Weiyi Huang, Chenling Shen, Yi Pan, Yiming Zhong, Bing Kong, Yilin Shen, Mingliang Xiang, Bin Ye   +8 more
wiley   +1 more source

Atypical structure of the nuclear membrane, distribution of nuclear pores and lamin B1 in spermatozoa of patients with complete and partial globozoospermia

Frontiers in Genetics
Globozoospermia is a form of male infertility characterized by spermatozoa with spherical heads lacking acrosomes. The aim of this study was to evaluate ultrastructural and molecular defects in different types of globozoospermia.
Elizaveta Bragina, Elizaveta Bragina, Svetlana Kurchashova, Marina Suhomlinova, Tatiana Gasanova, Svetlana Ermolaeva, Tatyana Sorokina, Eva Kirs, Evgeniy Arifulin, Olga Solovova, Oxana Ryzhkova, Sabina Khayat, Marina Andreeva, Vyacheslav Chernykh, Vyacheslav Chernykh   +14 more
doaj   +1 more source

hTERT Increases TRF2 to Induce Telomere Compaction and Extend Cell Replicative Lifespan

Aging Cell, EarlyView.
In contrast to the dogma that a subset of short telomeres initiates senescence, hTERT variants unable to maintain telomere length block senescence by stabilizing TRF2 via inhibiting upstream E3 ubiquitin ligases. This noncanonical hTERT function also compacts telomeres and blocks senescence‐associated DNA damage signaling. Cancer cells expressing hTERT
Nancy Adam, Yang Yang, Mahbod Djamshidi, Sara Seifan, Nicholas S. Y. Ting, Joel Glover, Nicolas Touret, Paul M. K. Gordon, K. V. Vineetha Warriyar, Hokan Krowicki, Christine Kim Garcia, Sharon A. Savage, Aaron A. Goodarzi, Duncan M. Baird, Tara L. Beattie, Karl Riabowol   +15 more
wiley   +1 more source