Results 151 to 160 of about 18,743 (257)

Correction: An evolutionarily conserved role for separase in the regulation of nuclear lamins. [PDF]

Cell Death Discov
Cipressa F, Pennarun G, Bosso G, Rosignoli S, Tullo L, Schiralli N, Di Dio C, Borghi C, Paiardini A, Esposito G, Goldberg ML, Bertrand P, Cenci G.   +12 more
europepmc   +1 more source

Decreased Glucose Metabolism and Declined Chaperones Are Unique Features Required for the Survival of Senescent Fibroblasts and Pyruvate Dehydrogenase Is a Potent Senolytic Target

Aging Cell, Volume 25, Issue 3, March 2026.
By a global proteomic profiling of senescent human BJ fibroblasts induced by ionizing radiation, key cellular features required for the survival of senescent fibroblasts were revealed, and pyruvate dehydrogenase was demonstrated as a potent senolytic target for selectively eliminating senescent normal cells, particularly the therapy‐induced senescent ...
Mingzhu Zhang, Ziqi Hu, Shengwen Piao, Yingrui Song, Ying Jia, Jiaxing Liu, Ning Zhao, An Liu, Songbin Fu, Wenjing Sun, Hui Xu, Yu Yang, Steven P. Gygi, Chunshui Zhou   +13 more
wiley   +1 more source

The dual guardians of cellular stability: exploring nesprin and lamin in senescence. [PDF]

Cell Death Dis
Zhou ZY, Qin Q, Dong C, Liu Y, Cao C, Teng L.   +5 more
europepmc   +1 more source

Ticks and tick‐borne bacterial pathogens found on hard ticks (Acari: Ixodidae) on cattle in the Central River region of The Gambia

Medical and Veterinary Entomology, Volume 40, Issue 1, Page 91-100, March 2026.
First detection of Ehrlichia minasensis, Anaplasma marginale and hemotropic Mycoplasma spp. in cattle in The Gambia. Identification of four tick species, with Hyalomma marginatum being the most common. 15.6% of ticks tested positive for tick‐borne pathogens, including Ehrlichia spp., A. marginale and hemotropic Mycoplasma spp.
Alpha Kargbo, Aamir M. Osman, Edrisa Jawo, Lamin K. M. Fatty, Flavia C. M. Collere, Marcos R. André, Ahmed A. Hassan‐Kadle, Thállitha S. W. J. Vieira, Rosangela Z. Machado, Rafael F. C. Vieira   +9 more
wiley   +1 more source

An evolutionarily conserved role for separase in the regulation of nuclear lamins. [PDF]

Cell Death Discov
Cipressa F, Pennarun G, Bosso G, Rosignoli S, Tullo L, Schiralli N, Di Dio C, Borghi C, Paiardini A, Esposito G, Goldberg ML, Bertrand P, Cenci G.   +12 more
europepmc   +1 more source

Senescent‐Like Myofibers Contribute to Anti‐Regenerative Cytokine Signaling in Duchenne Muscular Dystrophy

The FASEB Journal, Volume 40, Issue 4, 28 February 2026.
p16 expression in DMD model rats induces a senescent‐like state in myofibers accompanied by p16 and cytokine gene expression, reshaping systemic humoral environments. This cytokine‐rich milieu suppresses skeletal muscle regeneration, as demonstrated by impaired regeneration of transplanted wild‐type muscle.
Masanari Ikeda, Yukie Tanaka, Hidetoshi Sugihara, Takashi Matsuwaki, Keitaro Yamanouchi   +4 more
wiley   +1 more source

Nucleus softens during herpesvirus infection. [PDF]

PLoS Pathog
Tervonen A, Ruokolainen V, Leclerc S, Tieu K, Lyonnais S, Niskanen H, Chen JH, Gupta A, Kaikkonen MU, Larabell CA, Muriaux D, Mattola S, Conway DE, Ihalainen TO, Aho V, Vihinen-Ranta M.   +15 more
europepmc   +1 more source

Broken nuclei--lamins, nuclear mechanics, and disease.

Trends in Cell Biology, 2014
P. Davidson, J. Lammerding
semanticscholar   +1 more source

Unraveling Endocannabinoid Signaling Pathways in Cisplatin‐Induced Ototoxicity

The FASEB Journal, Volume 40, Issue 4, 28 February 2026.
We performed a comprehensive molecular profiling of the endocannabinoid (eCB) system (ECS) in an auditory Hair cell (HC)‐like cell line (1). Afterwards, we developed suitable in vitro and in vivo models of cisplatin‐induced ototoxicity where we identified distinct components of the ECS (CB2R, DAGLβ and ABHD6) as molecular targets of the drug (2 ...
Sakthimala Palaniappan, Annamaria Tisi, Camilla Di Meo, Cristina Urbano, Georgina E. Fenton, Francesco Della Valle, Federico Fanti, Dario Compagnone, Marc Nazarè, Huib Versnel, Andrea Aramini, Marcello Allegretti, Mauro Maccarrone   +12 more
wiley   +1 more source

Nuclear mechanobiology rules immune cells' functions: from differentiation to cell trafficking and pathogen killing. [PDF]

Nucleus
Renkawitz J, Yesin A, Kroll J, Cabral AT, D'Annunzio S, Thiam HR.   +5 more
europepmc   +1 more source