Results 41 to 50 of about 9,924 (194)
Lamins in Lung Cancer: Biomarkers and Key Factors for Disease Progression through miR-9 Regulation?
Cells, 2018 Lung cancer represents the primary cause of cancer death in the world. Malignant cells identification and characterization are crucial for the diagnosis and management of patients with primary or metastatic cancers. In this context, the identification of
Julien Guinde +8 more
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Cold Spring Harbor Perspectives in Biology, 2010 The nuclear lamins are type V intermediate filament proteins that are critically important for the structural properties of the nucleus. In addition, they are involved in the regulation of numerous nuclear processes, including DNA replication, transcription and chromatin organization.
Thomas, Dechat +4 more
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Characterization of lamin mutation phenotypes in Drosophila and comparison to human laminopathies. [PDF]
PLoS ONE, 2007 Lamins are intermediate filament proteins that make up the nuclear lamina, a matrix underlying the nuclear membrane in all metazoan cells that is important for nuclear form and function.
Andrés Muñoz-Alarcón +6 more
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Fundamenta Mathematicae, 2022 35 pages, 1 figure; keywords: complex dynamics, circle dynamics ...
Bhattacharya, Sourav +2 more
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Discovery and restoration of Aberrant Nuclear structure and Genome behaviour in breast cancer cells [PDF]
, 2013 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The eukaryotic interphase nucleus is well organised and the genome positioned non-randomly.
Hassan Ahmed, Mai
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An investigation of emerin and nuclear lamins: : Interactions, distribution, and role in cell cycle regulation, in cells derived from EDMD patients. [PDF]
, 2002 Emery Dreifuss muscular dystrophy (EDMD) is caused by mutations either in the gene encoding emerin or in the gene encoding A-type lamins (lamins A and C).
Maria, Choleza
core
The multiple roles of A-type lamins in cellular aging, cell cycle progression and the DNA damage response. [PDF]
, 2011 A-type lamins are a group of type V intermediate filaments whose main members are lamin A and C. Lamins A/C are components of the nuclear lamina and are encoded by the LMNA gene.
GIBBS-SEYMOUR, IAN,DAVID
core
Need for NAD+: Focus on Striated Muscle Laminopathies
Cells, 2020 Laminopathies are a heterogeneous group of rare diseases caused by genetic mutations in the LMNA gene, encoding A-type lamins. A-type lamins are nuclear envelope proteins which associate with B-type lamins to form the nuclear lamina, a meshwork ...
Déborah Cardoso, Antoine Muchir
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Frontiers in Cell and Developmental Biology, 2022 In eukaryotic cells, the genome is organized in the form of chromatin composed of DNA and histones that organize and regulate gene expression. The dysregulation of chromatin remodeling, including the aberrant incorporation of histone variants and their ...
A. K. Balaji +4 more
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The Nuclear Envelope as a Regulator of Immune Cell Function
Frontiers in Immunology, 2022 The traditional view of the nuclear envelope (NE) was that it represented a relatively inert physical barrier within the cell, whose main purpose was to separate the nucleoplasm from the cytoplasm.
Anna Selezneva +2 more
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