Results 61 to 70 of about 9,924 (194)
Scaffold, mechanics and functions of nuclear lamins
, 2023 Nuclear lamins are type-V intermediate filaments that are involved in many nuclear processes. In mammals, A- and B-type lamins assemble into separate physical meshwork underneath the inner nuclear membrane, the nuclear lamina, with some residual fraction
Thurston, Alice +6 more
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Lamins: the structure and protein complexes
, 2015 Lamins are nuclear intermediate filament (IF) proteins. They assemble to fibrous structures that are positioned between the inner nuclear membrane and the peripheral chromatin. A small fraction of lamins is also present in the nucleoplasm.
Medalia, Ohad +3 more
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B-type lamins in health and disease [PDF]
, 2014 For over two decades, B-type lamins were thought to have roles in fundamental processes including correct assembly of nuclear envelopes, DNA replication, transcription and cell survival.
Hutchison, Chris, Hutchison, C.J.
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iScienceSummary: Lamins A and C are components of the lamina at the nuclear periphery and associate with heterochromatin. A distinct, relatively mobile pool of lamin A/C in the nuclear interior associates with euchromatic regions and with lamin-associated ...
Daria Filipczak +4 more
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Clinical and genetic characteristics of hereditary laminopathies
Анналы клинической и экспериментальной неврологии, 2017 Naminopathies belong to a wide allelic series of diseases caused by mutations of one gene, LMNA, encoding for protein lamin A/C. Different mutations in the LMNA gene cause autosomal dominant and autosomal recessive EmeryDreifuss muscular dystrophy ...
E. L. Dadaly, D. S. Bileva, I. V. Ugarov
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, 2022 The nuclei of multinucleated skeletal muscles experience substantial external force during development and muscle contraction. Protection from such forces is partly provided by lamins, intermediate filaments that form a scaffold lining the inner nuclear ...
Jose L. Rios-Monterrosa (13540525) +6 more
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Microtubular and Nuclear Functions of γ-Tubulin: Are They LINCed?
Cells, 2019 γ-Tubulin is a conserved member of the tubulin superfamily with a function in microtubule nucleation. Proteins of γ-tubulin complexes serve as nucleation templates as well as a majority of other proteins contributing to centrosomal and non ...
Jana Chumová +4 more
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, 2022 The nuclei of multinucleated skeletal muscles experience substantial external force during development and muscle contraction. Protection from such forces is partly provided by lamins, intermediate filaments that form a scaffold lining the inner nuclear ...
Jose L. Rios-Monterrosa (13540525) +6 more
core +1 more source
Novel Roles for A-Type Lamins in Maintaining Genomic Stability [PDF]
, 2012 A-type lamins, key structural components of the nucleus, have been implicated in the maintenance of nuclear architecture and chromatin organization. Mutations in A-type lamins have been associated with defects in a number of nuclear processes, including ...
Redwood, Abena
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Nuclear Mechanics and Nuclear Mechanotransduction in Cancer Cell Migration and Invasion
BiomoleculesNuclear mechanics and mechanotransduction are involved in the migration and invasion process, such as those in which the cells need to deform themselves to pass through constrictions.
Claudia Tanja Mierke
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