Results 31 to 40 of about 791 (182)

K<sup>+</sup> Channels and Some Familiar Antiepileptic Drugs: Evaluation of Their the Structure-Activity Relationships with Molecular Docking Analysis [PDF]

open access: yes, 2023
This study includes the structure-activity relationship of active molecules that are commonly used in the treatment of convulsive seizures in epileptic diseases.
Çakmak E.N., Gür M., Kiran B.
core   +1 more source

Evaluation of Bladder Wash as an Alternative Specimen for Postmortem Toxicology: Comparison to Screening Results of Urine and Kidney Tissue

open access: yesDrug Testing and Analysis, Volume 17, Issue 9, Page 1640-1655, September 2025.
Urine specimens represent the gold standard for screening analyses in forensic toxicology but are not always available postmortem. The current study systematically evaluated bladder wash (BW) as an interesting, but largely unexplored specimen for screening, in comparison to urine and kidney tissue (KT).
Andrea E. Steuer   +4 more
wiley   +1 more source

Dravet syndrome: a new causative SCN1A mutation?

open access: yesClinical Case Reports, Volume 5, Issue 5, Page 613-615, May 2017., 2017
Key Clinical Message Dravet syndrome is often caused by SCN1A mutations and has a wide variation in clinical appearance. Indication for genetic analysis should be an epileptic encephalopathy or severe clinical course of seizures in infants with episodes of fever before the first year of life.
Martin Poryo   +5 more
wiley   +1 more source

Faktorer av betydning for variasjon i serumkonsentrasjonen av lamotrigin og lamotrigin 2-N-glukuronid [PDF]

open access: yes, 2013
Bakgrunn: Lamotrigin brukes i behandling av epilepsi og bipolar lidelse, og utviser betydelig farmakokinetisk variasjon. Metabolismen av lamotrigin skjer i stor grad via enzymet UGT1A4.
Chan, Hilde Fauskrud
core  

Moderne medikamentöse Epilepsietherapie im Alter [PDF]

open access: yes, 2009
ZusammenfassungJenseits des 60. Lebensjahres beginnen ein Drittel aller Neuerkrankungen an Epilepsie. Die Behandlung mit Antiepileptika ist durch Veränderungen der Pharmakokinetik und Pharmakodynamik in dieser Patientengruppe besonders ...
H. M. Hamer   +4 more
core   +1 more source

Time after time: failure to identify and support females with ADHD – a Swedish population register study

open access: yesJournal of Child Psychology and Psychiatry, Volume 65, Issue 6, Page 832-844, June 2024.
Background Attention deficit hyperactivity disorder (ADHD) is associated with risk taking and negative health‐related outcomes across the lifespan. Due to delay in referral and diagnostics, young females with ADHD may not be identified, nor appropriately supported by adequate interventions.
Charlotte Skoglund   +7 more
wiley   +1 more source

Sikkerhetsfarmakologiske studier av lamotrigin og valproat - mulige effekter på nevronkulturer [PDF]

open access: yes, 2013
Det foreligger som regel lite dokumentasjon på legemidler sin innvirkning på sentralnervesystemet under utvikling, og det er anbefalt at det utvikles nye metoder for å studere dette.
Evensen, Sissel
core  

Epilepsie [PDF]

open access: yes, 2012
ZusammenfassungEpilepsien gehören zu den häufigsten neurologischen Erkrankungen. Die Therapie erfolgt in erster Linie symptomatisch durch Medikamente, die anhand des Epilepsiesyndroms, der Nebenwirkungen und individuellen Patientenbedürfnisse ausgewählt ...
H. Lerche, S. Klamer, Y. G. Weber
core   +1 more source

Prescription patterns characteristics of new antiepileptic drugs

open access: yesArchivo Médico de Camagüey, 2018
Background: epilepsy is one of the most frequent neurological diseases and almost 30 % of patients who suffer from it do not get control with classic antiepileptic drugs.
Tania García Arias   +5 more
doaj  

Effekten av kombinasjonsbehandling med valproat og lamotrigin på serumkonsentrasjonen av atypiske antipsykotika og deres metabolitter - en retrospektiv studie basert på data fra terapeutisk legemiddelmonitorering [PDF]

open access: yes, 2016
Bakgrunn: Valproat og lamotrigin er «stemningsstabiliserende» antiepileptika som benyttes mye i kombinasjon med antipsykotika ved bipolar sykdom og schizoaffektive lidelser.
Kyllesø, Lennart
core  

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