Results 71 to 80 of about 19,789 (243)

Cognitive effects of lamotrigine versus topiramate as adjunctive therapy in older adults with epilepsy

open access: yesNeurology International, 2009
Older individuals may be more susceptible to cognitive side effects of antiepileptic drugs than are younger adults. This randomized, double-blind study compared the cognitive effects of lamotrigine (median maintenance dosage, 500.0 mg/d) and topiramate ...
Steve S. Chung   +3 more
doaj   +1 more source

Efficacy of Lamotrigin in Treatment of Avoidance / Numbing in Post-traumatic Stress Disorders

open access: yesArmaghane Danesh Bimonthly Journal, 2006
: Introduction & Objective: Post-traumatic stress disorder (PTSD) is a chronic illness which is difficult to treat yet, it is a common disorder which is associated with significant morbidity and mortality. The hypothesis that exposure to traumatic events
S Amanat, H Afshar
doaj  

The burden of the postictal state in epilepsy: A prospective, single‐center observational cohort study

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective The postictal state is a major yet underrecognized component of the epilepsy burden. We aimed to develop a structured patient‐reported instrument to quantify postictal recovery, characterize its multidimensional burden, and identify demographic, clinical, psychiatric, and treatment‐related factors associated with postictal severity ...
Ionuț‐Flavius Bratu   +2 more
wiley   +1 more source

Genetic testing among patients evaluated for epilepsy surgery

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective Genetic testing performed to identify the underlying etiology of epilepsy has become increasingly common and is now being recommended as part of the presurgical evaluation for epilepsy surgery. This study aimed to characterize the types of genetic tests performed in patients evaluated for epilepsy surgery and assess how genetic ...
Anni Saarela   +7 more
wiley   +1 more source

The effectiveness of adding on or switching antiseizure medications after the first fails to control focal epilepsy: A systematic review of randomized controlled trials

open access: yesEpileptic Disorders, EarlyView.
Abstract Focal epilepsy constitutes 60–70% of epilepsy, and up to half of patients do not achieve seizure freedom with their first antiseizure medication (ASM). When the first ASM fails, evidence guiding whether to switch or add‐on another ASM and which ASMs to use is limited. This review synthesized evidence from randomized controlled trials (RCTs) on
Isaac J. Egesa   +7 more
wiley   +1 more source

KBG syndrome: A scoping review of electroclinical features of patients with epilepsy

open access: yesEpileptic Disorders, EarlyView.
Abstract Background and Objectives KBG syndrome is a rare autosomal developmental disorder caused by pathogenic variants of the ANKRD11 gene. This scoping review aimed to explore all current literature data regarding clinical and electroencephalographic features of patients with KBG syndrome and epilepsy. Materials and Methods We conducted a literature
Stefania Kalampokini   +6 more
wiley   +1 more source

Unique EEG signature of atypical absence seizures in SYNGAP1‐related developmental and epileptic encephalopathy

open access: yes
Epileptic Disorders, EarlyView.
Rainier Mark Loidor L. Rapal   +2 more
wiley   +1 more source

Management of ring chromosome 20 syndrome: Narrative review and consensus recommendations

open access: yesEpilepsia, EarlyView.
Abstract Ring chromosome 20 (ring 20) is a rare genetic condition usually presenting as developmental and epileptic encephalopathy. The disease is caused by fusion of the long and short arms of chromosome 20. Patients are symptomatic even if there is no loss of genetic material.
Asma Khamis   +8 more
wiley   +1 more source

Predicting seizure freedom in the postpartum period: Findings from the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs study

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate whether seizure freedom in pregnancy predicts seizure freedom in the postpartum period in women with epilepsy (WWE). Prior studies have shown that seizure freedom prior to conception strongly predicts seizure freedom during pregnancy.
Emma C. Osterhaus   +7 more
wiley   +1 more source

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