Results 61 to 70 of about 19,789 (243)

Acute neural effects of the mood stabiliser lamotrigine on emotional processing in healthy volunteers: a randomised control trial

Translational Psychiatry
Lamotrigine is an effective mood stabiliser, largely used for the management and prevention of depression in bipolar disorder. The neuropsychological mechanisms by which lamotrigine acts to relieve symptoms as well as its neural effects on emotional ...
Marieke A. G. Martens, Tarek Zghoul, Evelyn Watson, Sebastian W. Rieger, Liliana P. Capitão, Catherine J. Harmer   +5 more
doaj   +1 more source

A comparison before and after lamotrigine use in long term continuation treatment: effect of blood level

Psychiatry and Behavioral Sciences, 2013
Objective: The hypothesis of this study is that the efficacy of lamotrigine is related with blood level in bipolar disorder. Our aim is to compare the periods before and after lamotrigine use in cases with bipolar disorder and to investigate whether ...
Sermin Kesebir, Fisun Akdeniz, Aysun Demir, Mustafa Bilici   +3 more
doaj   +1 more source

De novo TANC2 stop‐loss variant associated with developmental impairment and drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Matthew A. Hintermayer, Kenneth A. Myers
wiley   +1 more source

Preoperative limbic cortical thinning in mesial temporal lobe epilepsy surgical candidates is associated with pre‐existing and de novo postoperative depression

Epileptic Disorders, EarlyView.
Abstract Objective Depression is common in mesial temporal lobe epilepsy (mTLE), but its neuroanatomical basis—and overlap with major depressive disorder (MDD)—remains poorly defined. We investigated whether the cortical and subcortical alterations reported in MDD are also present in mTLE and leveraged the frequent occurrence of depression after ...
Philip Fink‐Jensen, Brice Ozenne, Ane Kloster, Bo Jespersen, Kirsten Vinter, Guido Rubboli, Martin Balslev Jørgensen, Sandor Beniczky, Melanie Ganz, Lars Hageman Pinborg   +9 more
wiley   +1 more source

Failure of Ketamine Anesthesia in a Patient with Lamotrigine Overdose

Case Reports in Critical Care, 2014
Introduction. It is important to know which clinical situations prevent ketamine from working. Case Report. We present the case of the psychiatric inpatient who was admitted to our emergency department after ingesting a toxic dose of lamotrigine, unknown
Daniel Kornhall, Erik Waage Nielsen
doaj   +1 more source

Epileptic encephalopathy with spike‐and‐wave activation in sleep associated with Tatton–Brown–Rahman syndrome responsive to highly purified cannabidiol

Epileptic Disorders, EarlyView.
Anita N. Datta
wiley   +1 more source

NMDAR‐antibody encephalitis: Seizure semiology and EEG findings

Epileptic Disorders, EarlyView.
Abstract Background N‐methyl‐D‐aspartate receptor antibody encephalitis (NMDAR‐Ab‐E) is an autoantibody‐mediated disorder, characterized by acute development of neuropsychiatric symptoms, seizures, movement disorders, and autonomic instability. Objectives To describe acute seizure semiology and electroencephalogram (EEG) findings in patients with a ...
Maria Emilia C. Andraus, Bernard Liem, Sidra Aurangzeb, Mkael Symmonds, Adam E. Handel, Sarosh R. Irani, Arjune Sen   +6 more
wiley   +1 more source

Cardiac Electrophysiological Effects of the Sodium Channel-Blocking Antiepileptic Drugs Lamotrigine and Lacosamide

Pharmaceuticals
Background: The two antiepileptic drugs lacosamide and lamotrigine exert their antiepileptic effect by inhibiting sodium channels. Lacosamide enhances the inactivation of sodium channels, while lamotrigine inhibits the activation of the channel ...
Julian Wolfes, Philipp Achenbach, Felix K. Wegner, Benjamin Rath, Lars Eckardt, Gerrit Frommeyer, Christian Ellermann   +6 more
doaj   +1 more source

Multi-Omics in Predicting Lamotrigine Neurotoxicity: Current Opportunities (Review)

Безопасность и риск фармакотерапии
INTRODUCTION. Lamotrigine (LTG) is among the most commonly prescribed second-generation antiepileptic drugs due to its low teratogenic risk. However, lamotrigine has pronounced neurotoxic, hepatotoxic, dermatotoxic potential (for genetic and metabolic ...
N. A. Shnayder, V. V. Bader, R. F. Nasyrova, M. Ya. Kissin   +3 more
doaj   +1 more source

Lamotrigine Augmentation of Serotonin Reuptake Inhibitors in Severe and Long-Term Treatment-Resistant Obsessive-Compulsive Disorder

Case Reports in Psychiatry, 2013
The treatment recommendations in obsessive-compulsive disorder (OCD) after lack of response to selective serotonin reuptake inhibitors (SSRIs) include augmentation with other drugs, particularly clomipramine, a more potent serotonin reuptake inhibitor ...
Manuel Arrojo-Romero, María Tajes Alonso, Jose de Leon   +2 more
doaj   +1 more source