Results 41 to 50 of about 20,608 (229)

Severe Cutaneous Adverse Reactions Associated With High-Dose Lamotrigine for Mood Disorders: A Case Series

open access: yesINNOVATIONS in Pharmacy, 2022
Drug-induced Eosinophilia and Systemic Symptoms (DRESS), Stevens-Johnson Syndrome (SJS), and Toxic Epidermal Necrolysis (TEN) are rare but life-threatening immune-mediated drug reactions known as Severe Cutaneous Adverse Reactions (SCARs).
Abigale Clark, Blake St. Clair
doaj  

Hypotonia and poor feeding in an infant exposed to lamotrigine and valproic acid in utero

open access: yesThe Turkish Journal of Pediatrics, 2013
Lamotrigine has been considered a safe new-generation antiepileptic drug during the perinatal period for both mothers and infants. Despite the concerns regarding its possible teratogenic effect, very limited data have been reported on the adverse ...
Sahin Takcı   +3 more
doaj   +1 more source

Data on the relationship between lamotrigine and levetiracetam serum/plasma levels and toxicity: Experience at an academic medical center

open access: yesData in Brief, 2021
Lamotrigine and levetiracetam are second-generation anti-epileptic drugs used for the management of seizure disorders and some other medical conditions. In the related research article using retrospective data from an academic medical center, we analyzed
Kelly E. Wood   +2 more
doaj   +1 more source

Efficacy of Lamotrigine in the Treatment of Unipolar and Bipolar Depression: Meta-Analysis of Acute and Maintenance Randomised Controlled Trials

open access: yesPharmaceuticals
Background/Objectives: Lamotrigine has been widely investigated in the treatment and prevention of the emergence of symptoms of depression in unipolar and bipolar depression.
Danilo Arnone   +6 more
doaj   +1 more source

Evaluation of antiseizure drug efficacy and tolerability in the rat lamotrigine‐resistant amygdala kindling model

open access: yesEpilepsia Open, 2019
Objective The lamotrigine‐resistant amygdala kindling model uses repeated administration of a low dose of lamotrigine during the kindling process to produce resistance to lamotrigine, which also extends to some other antiseizure drugs (ASDs).
Cameron S. Metcalf   +5 more
doaj   +1 more source

The hidden burden of sleep in adolescents with idiopathic generalized epilepsy

open access: yesEpileptic Disorders, EarlyView.
Abstract Background Idiopathic Generalized Epilepsies (IGEs) are electroclinical syndromes characterized by distinct seizure types, EEG patterns, and presumed polygenic inheritance. While seizure prognosis is often favorable, sleep disturbances, behavioral and emotional difficulties, and executive function impairment are common, especially during ...
Carlo Alberto Quaranta   +8 more
wiley   +1 more source

Treatment Effects of Onion (Allium cepa) and Ginger

open access: yesBalkan Medical Journal, 2012
Objective: The aim of the present study was to evaluate the beneficial degree of sexual behavior in male rats after inducement of onion and ginger in lamotrigine receiving groups.
Hussein Nikniaz   +3 more
doaj  

The use of intralipid emulsion therapy to treat severe cardiotoxicity secondary to lamotrigine ingestion in a dog

open access: yesClinical Case Reports, 2018
Key Clinical Message Lamotrigine is a sodium and calcium channel blocker, used to treat seizures in people. Dogs metabolize Lamotrigine to a cardiotoxic metabolite that causes severe, often fatal ventricular arrhythmias.
Tara J. Bellis, Laura Gibeon
doaj   +1 more source

Add-on Lamotrigine Treatment for Subsyndromal Depression after Manic or Mixed States in Bipolar Disorder Improved the Quality of Life

open access: yesCase Reports in Medicine, 2012
Two cases of patients experienced subsyndromal depression after manic or mixed hypomanic and depressive episodes due to bipolar I (case 1) and II (case 2) disorders prior to the use of lamotrigine.
Katsumasa Muneoka   +6 more
doaj   +1 more source

Toxic epidermal necrolysis induced by lamotrigine treatment in a child [PDF]

open access: yesKorean Journal of Pediatrics, 2014
Toxic epidermal necrolysis is an unpredictable and severe adverse drug reaction. In toxic epidermal necrolysis, epidermal damage appears to result from keratinocyte apoptosis.
Youngsuk Yi, Jeong Ho Lee, Eun Sook Suh
doaj   +1 more source

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