Results 41 to 50 of about 24,362 (263)

Adherence to and persistence with lacosamide, perampanel, lamotrigine, and levetiracetam in adult patients with focal epilepsy in Japan: A descriptive cohort study using a claims database

Heliyon, 2023
Objective: We evaluated adherence to and 1-year persistence of two third-generation anti-seizure medications (ASMs), lacosamide and perampanel, in adult patients with focal epilepsy, compared with lamotrigine and levetiracetam.
Siming Chen, Toshiki Fukasawa, Akio Ikeda, Masato Takeuchi, Akihiro Shimotake, Satomi Yoshida, Koji Kawakami   +6 more
doaj   +1 more source

A pilot open series of lamotrigine in DBT-treated eating disorders characterized by significant affective dysregulation and poor impulse control

Borderline Personality Disorder and Emotion Dysregulation, 2017
Background There is little effective psychopharmacological treatment for individuals with eating disorders who struggle with pervasive, severe affective and behavioral dysregulation. Methods This pilot open series evaluated lamotrigine, a mood stabilizer,
Mary Ellen Trunko, Terry A. Schwartz, Laura A. Berner, Anne Cusack, Tiffany Nakamura, Ursula F. Bailer, Joanna Y. Chen, Walter H. Kaye   +7 more
doaj   +1 more source

Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin

Clinical Case Reports, 2021
Lamotrigine has been repeatedly reported to cause hematologic toxicities, which may be associated with high initial doses or excessive escalation. A 29‐year‐old lady experienced profound neutropenia after two weeks of lamotrigine high initial dose ...
Muhammad Salem, Ahmed El‐Bardissy
doaj   +1 more source

Beneficial cognitive effect of lamotrigine in severe acquired brain injury: A case report

Interdisciplinary Neurosurgery, 2021
Background: Acquired brain injuries (ABI) can cause various negative sequelae, including cognitive impairment, leading to poor functional outcomes for patients.
Maxwell Ng, Sheliza Ali, Joanna Sue, Nora Cullen, Scott McCullagh, Gihan Perera, Hossein Hosseini, Flor Muniz-Rodriguez, Zhihui Deng   +8 more
doaj   +1 more source

Clinical, Behavioral and Neuroradiological Phenotype in an Italian Cohort of Patients With Xia Gibbs Syndrome: A Multicenter Cross‐Sectional Study and Systematic Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous variants in the AHDC1 gene are associated with Xia Gibbs Syndrome (XGS), a genetic disorder with a highly variable phenotype. Cognitive impairment, motor delay, language delay, neonatal hypotonia, and sleep apnea are considered “cardinal” signs of the disease.
Giulia Cinelli, Stefania Della Vecchia, Patrizia Bergonzini, Elisa Caramaschi, Elisabetta Spezia, Claudia Parenti, Simona Filomena Madeo, Laura Lucaccioni, Cavalleri Francesca, Marisa Pugliese, Federico Raviglione, Clara Colonna, Olga Calabrese, Ilaria Stanghellini, Maria Carmen Marongiu, Enrico Biagioni, Anna Rita Ferrari, Roberta Battini, Lorenzo Iughetti   +18 more
wiley   +1 more source

Lamotrigine-induced sexual dysfunction and non-adherence: case analysis with literature review

BJPsych Open, 2017
Background Optimal anti-epileptic drug (AED) treatment maximises therapeutic response and minimises adverse effects (AEs). Key to therapeutic AED
Kenneth R. Kaufman, Melissa Coluccio, Kartik Sivaraaman, Miriam Campeas   +3 more
doaj   +1 more source

Melatonin Levels in 89 Individuals With Smith Magenis Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT In patients with Smith–Magenis syndrome (SMS), an inverted circadian rhythm of melatonin (MT) contributes to the sleep disturbance. Standard treatment of sleep disturbance with MT often leads to extremely high daytime MT levels, resulting in even more sleep disorders. We therefore retrospectively evaluated the MT data of 89 SMS patients.
Wiebe Braam, Ann C. M. Smith
wiley   +1 more source

Evaluation of immunomodulatory effects of lamotrigine in BALB/c mice

Acta Pharmaceutica, 2017
Modulation of the immune system has recently been shown to be involved in the pharmacological effects of old antiepileptic drugs and in the pathogenesis of epilepsy.
Abu-Rish Eman Y., Elhayek Shada Y., Mohamed Yehia S., Hamad Islam, Bustanji Yasser   +4 more
doaj   +1 more source

Electrocardiographic Evaluation in Patients Receiving Lamotrigine Monotherapy/Duotherapy

Archives of Epilepsy, 2023
Objective:Despite its widespread use and safety data, the cardiac safety of lamotrigine was brought into question in October 2020 when the U.S. Food and Drug Administration issued a safety warning about its cardiac side effects.
Merve Hazal Ser, Bengi Gül Türk, Özgür Selim Ser, Seher Naz Yeni   +3 more
doaj   +1 more source

Lamotrigine et éthinylestradiol

, 2021
International audience*auteur correspondant • Conflits d'intérêts : Les auteurs déclarent ne pas avoir de liens d'intérêts. Résumé La mise en place d'une contraception estroprogestative chez une patiente traitée par lamotrigine peut entrainer une ...
Legeay, Samuel, Faure, Sébastien
core   +1 more source