Results 51 to 60 of about 19,789 (243)
Key Clinical Message Lamotrigine is a sodium and calcium channel blocker, used to treat seizures in people. Dogs metabolize Lamotrigine to a cardiotoxic metabolite that causes severe, often fatal ventricular arrhythmias.
Tara J. Bellis, Laura Gibeon
doaj +1 more source
Abstract Background and Objectives Muscle‐Eye‐Brain disease (MEB) is a dystroglycanopathy that belongs to the congenital muscular dystrophies. Central nervous system manifestations include congenital brain abnormalities, neurodevelopmental delay, and epilepsy, making it a rare but important cause of developmental and epileptic encephalopathy.
Stefania Kalampokini +6 more
wiley +1 more source
Two cases of patients experienced subsyndromal depression after manic or mixed hypomanic and depressive episodes due to bipolar I (case 1) and II (case 2) disorders prior to the use of lamotrigine.
Katsumasa Muneoka +6 more
doaj +1 more source
A guide to neuromodulation in drug‐resistant epilepsy
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh +10 more
wiley +1 more source
The second unprovoked seizure in a cohort of treated patients with a first unprovoked seizure
Abstract Objectives To evaluate the rate of a second unprovoked seizure in antiseizure medications (ASMs)‐treated patients following a first unprovoked seizure and to identify potential risk factors associated with its occurrence. Methods A retrospective review of the computerized database and the medical records of all the patients who presented to ...
Revital Gandelman‐Marton +1 more
wiley +1 more source
The outcomes of consecutive pregnancies in Australian women with epilepsy
Abstract Objective To investigate the extent to which seizure control and the occurrence of fetal malformation in an initial pregnancy can serve to anticipate the outcome in the next pregnancy. Methods We analyzed the records of the Raoul Wallenberg Australian Register of Antiepileptic Drugs in Pregnancy for seizure control and fetal malformation data ...
Frank Vajda +7 more
wiley +1 more source
Objectives:Epileptics, especially children, are more prone to behavioural deficits. Epilepsy related factors, psychosocial problems, treatment side effects may aggravate such deficits.
Mehmet Fatih GÖL +3 more
doaj +1 more source
Abstract This seminar addresses the complexity of the management of epilepsy in adults with intellectual development disorders (IDD), advocating holistic and multidisciplinary care aligned with the learning objectives of the International League Against Epilepsy. Epilepsy is significantly more prevalent in people with IDD, presenting unique diagnostic,
Elena Fonseca +10 more
wiley +1 more source
Abstract Objective To evaluate the diagnostic utility and genetic spectrum of next‐generation sequencing (NGS) in a large, well‐phenotyped cohort of Turkish pediatric patients with epilepsy of unknown etiology. Methods Between January 2021 and December 2024, 250 children (115 female, 135 male) with unexplained epilepsy underwent either whole‐exome ...
Derya Karaer +4 more
wiley +1 more source
The hidden burden of sleep in adolescents with idiopathic generalized epilepsy
Abstract Background Idiopathic Generalized Epilepsies (IGEs) are electroclinical syndromes characterized by distinct seizure types, EEG patterns, and presumed polygenic inheritance. While seizure prognosis is often favorable, sleep disturbances, behavioral and emotional difficulties, and executive function impairment are common, especially during ...
Carlo Alberto Quaranta +8 more
wiley +1 more source

