Results 21 to 30 of about 19,789 (243)

Adherence to and persistence with lacosamide, perampanel, lamotrigine, and levetiracetam in adult patients with focal epilepsy in Japan: A descriptive cohort study using a claims database

Heliyon, 2023
Objective: We evaluated adherence to and 1-year persistence of two third-generation anti-seizure medications (ASMs), lacosamide and perampanel, in adult patients with focal epilepsy, compared with lamotrigine and levetiracetam.
Siming Chen, Toshiki Fukasawa, Akio Ikeda, Masato Takeuchi, Akihiro Shimotake, Satomi Yoshida, Koji Kawakami   +6 more
doaj   +1 more source

A pilot open series of lamotrigine in DBT-treated eating disorders characterized by significant affective dysregulation and poor impulse control

Borderline Personality Disorder and Emotion Dysregulation, 2017
Background There is little effective psychopharmacological treatment for individuals with eating disorders who struggle with pervasive, severe affective and behavioral dysregulation. Methods This pilot open series evaluated lamotrigine, a mood stabilizer,
Mary Ellen Trunko, Terry A. Schwartz, Laura A. Berner, Anne Cusack, Tiffany Nakamura, Ursula F. Bailer, Joanna Y. Chen, Walter H. Kaye   +7 more
doaj   +1 more source

Lamotrigine‐induced neutropenia after high‐dose concomitant initiation with phenytoin

Clinical Case Reports, 2021
Lamotrigine has been repeatedly reported to cause hematologic toxicities, which may be associated with high initial doses or excessive escalation. A 29‐year‐old lady experienced profound neutropenia after two weeks of lamotrigine high initial dose ...
Muhammad Salem, Ahmed El‐Bardissy
doaj   +1 more source

Interactions Between Lamotrigine and Contraceptives – Communication Practises

BJPsych Open
Aims This audit assesses communication practices regarding interactions between lamotrigine and oral contraceptives in North West Sussex (NWS) Specialist Perinatal Mental Health Services (SPMHS). The predicted outcome includes increasing awareness about
Samina Monir, Cissy Atwine, Helen Hutchings, Michael Harris   +3 more
doaj   +1 more source

Lamotrigine-induced sexual dysfunction and non-adherence: case analysis with literature review

BJPsych Open, 2017
Background Optimal anti-epileptic drug (AED) treatment maximises therapeutic response and minimises adverse effects (AEs). Key to therapeutic AED
Kenneth R. Kaufman, Melissa Coluccio, Kartik Sivaraaman, Miriam Campeas   +3 more
doaj   +1 more source

Beneficial cognitive effect of lamotrigine in severe acquired brain injury: A case report

Interdisciplinary Neurosurgery, 2021
Background: Acquired brain injuries (ABI) can cause various negative sequelae, including cognitive impairment, leading to poor functional outcomes for patients.
Maxwell Ng, Sheliza Ali, Joanna Sue, Nora Cullen, Scott McCullagh, Gihan Perera, Hossein Hosseini, Flor Muniz-Rodriguez, Zhihui Deng   +8 more
doaj   +1 more source

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi, Enrique Gonzalez Saez‐Diez, Joshua Rong, Beril Ay, Shabbir Merchant, Kathryn Yang, Darius Ebrahimi‐Fakhari   +6 more
wiley   +1 more source

Melatonin Levels in 89 Individuals With Smith Magenis Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT In patients with Smith–Magenis syndrome (SMS), an inverted circadian rhythm of melatonin (MT) contributes to the sleep disturbance. Standard treatment of sleep disturbance with MT often leads to extremely high daytime MT levels, resulting in even more sleep disorders. We therefore retrospectively evaluated the MT data of 89 SMS patients.
Wiebe Braam, Ann C. M. Smith
wiley   +1 more source

Understanding the behavior of a potential anticancer lamotrigine in explicit solvent (water and DMSO) using quantum mechanical tools and abinitio molecular dynamics

Chemical Physics Impact
Lamotrigine is a medication used to treat epilepsy and help stabilize mood in individuals with bipolar disorder. Epilepsy includes different types of seizures, such as focal seizures, tonic-clonic seizures, and Lennox-Gastaut syndrome, and Lamotrigine is
Elham S. Aazam, Renjith Thomas
doaj   +1 more source

Evaluation of immunomodulatory effects of lamotrigine in BALB/c mice

Acta Pharmaceutica, 2017
Modulation of the immune system has recently been shown to be involved in the pharmacological effects of old antiepileptic drugs and in the pathogenesis of epilepsy.
Abu-Rish Eman Y., Elhayek Shada Y., Mohamed Yehia S., Hamad Islam, Bustanji Yasser   +4 more
doaj   +1 more source