Results 21 to 30 of about 43,194 (232)

Pharmacokinetic, pharmacodynamic, and neurochemical investigations of lamotrigine‐pentylenetetrazole kindled mice to ascertain it as a reliable model for clinical drug‐resistant epilepsy

open access: yesAnimal Models and Experimental Medicine, 2020
Background Pentylenetetrazole kindling has long been used for the screening of investigational antiseizure drugs. The presence of lamotrigine, at a very low dose, does not hamper kindling in mice; rather it modifies this epileptogenesis process into drug‐
Sandeep Kumar, Rajesh K. Goel
doaj   +1 more source

Ketamine and Lamotrigine Combination in Psychopharmacology: Systematic Review

open access: yesCells, 2022
Background and Objectives: Ketamine is a rapid-acting antidepressant with proven efficacy as an add-on agent in unipolar and bipolar treatment-resistant depression.
Alina Wilkowska   +3 more
doaj   +1 more source

Action Tremor Associated with Lamotrigine Monotherapy [PDF]

open access: yesJournal of Movement Disorders, 2010
Lamotrigine (LTG) is associated with a tremor when given in combination with valproic acid; however, a tremor associated with lamotrigine monotherapy is rare. Here, we report a case of positional and action tremor associated with lamotrigine use.
Ji-Hye Yang   +2 more
doaj   +1 more source

Female genital disorder as adverse symptom of lamotrigine treatment - A serotoninergic effect? [PDF]

open access: yes, 1998
The new anticonvulsant, lamotrigine, is becoming an important tool in the treatment of bipolar disorder, including bipolar depression. Its efficacy in bipolar depression might be linked to its inhibition of serotonin uptake.
Amann, Benedikt   +2 more
core   +1 more source

May lamotrigine be an alternative to topiramate in the prevention of migraine with aura? Results of a retrospective study

open access: yesBMJ Neurology Open, 2020
Background Evidence suggests that lamotrigine could be effective in reducing aura frequency and duration. However, studies comparing lamotrigine to other, first-line prophylactic agents solely involving patients suffering from migraine with aura are ...
Francesco Janes   +3 more
doaj   +1 more source

Lamotrigine in the treatment of schizoaffective disorder [PDF]

open access: yes, 1998
There is accumulating evidence for the efficacy of lamotrigine in the treatment of bipolar disorder, including bipolar depression, both as monotherapy and in combination with sodium valproate.
Erfurth, Andreas   +2 more
core   +1 more source

Lamotrigine treatment of aggression in female borderline patients, Part II: an 18-month follow-up [PDF]

open access: yes, 2008
Borderline patients often display pathological aggression. We previously tested lamotrigine, an anti-convulsant, in therapy for aggression in women with borderline personality disorder (BPD) (J Psychopharmacol 2005; 19: 287–291), and found significant ...
Calabrese J.R.   +6 more
core   +1 more source

New insights into the mechanisms and sites of action of lamotrigine [PDF]

open access: yes, 2000
This study was aimed at investigating the effects of lamotrigine (LTG) on electrically evoked field excitatory postsynaptic potentials (fEPSP) and population spikes in the CA1 hippocampal region of guinea pigs.
Grunze, Heinz   +3 more
core   +1 more source

Teratogenic risk and contraceptive counselling in psychiatric practice: analysis of anticonvulsant therapy [PDF]

open access: yes, 2013
<p>Background: Anticonvulsants have been used to manage psychiatric conditions for over 50 years. It is recognised that some, particularly valproate, carbamazepine and lamotrigine, are human teratogens, while others including topiramate require ...
A Basan   +23 more
core   +2 more sources

Long-term effect of antiepileptic drug switch on serum lipids and C-reactive protein. [PDF]

open access: yes, 2016
BACKGROUND: Prior studies have shown that switching patients from inducing antiepileptic drugs (AEDs) to lamotrigine, levetiracetam, or topiramate reduces serum lipids and C-reactive protein (CRP). These studies were all of short duration, and some drugs,
Chervoneva, Inna   +6 more
core   +2 more sources

Home - About - Disclaimer - Privacy