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Is ketamine and lamotrigine interactions responsible for the sub-therapeutic effect of ketamine?
European Psychiatry, 2021 Introduction The immediate antidepressant effect of Ketamine has become a breakthrough in the treatment of depression. Cytochrome CYP3A4 and 2B6 primarily metabolize Ketamine.
M. Adnan +4 more
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Lamotrigine Effects on Breastfed Infants
Acta Medica Iranica, 2015 Lamotrigine is a safe anti-epileptic drug among pregnant and lactating women. Some concerns exist regarding the safety of lamotrigine during breastfeeding and related neonatal complications.
Hosein Dalili +3 more
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Animal Models and Experimental Medicine, 2020 Background Pentylenetetrazole kindling has long been used for the screening of investigational antiseizure drugs. The presence of lamotrigine, at a very low dose, does not hamper kindling in mice; rather it modifies this epileptogenesis process into drug‐
Sandeep Kumar, Rajesh K. Goel
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A Rare Side Effect of Lamotrigine: Hallucination
, 2021 Lamotrigine is an antiepileptic drug with a broad spectrum. Although the drug is safe, it sometimes has certain side effects that may limit its usage.
Hatice Ferhan KÖMÜRCÜ
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Ketamine and Lamotrigine Combination in Psychopharmacology: Systematic Review
Cells, 2022 Background and Objectives: Ketamine is a rapid-acting antidepressant with proven efficacy as an add-on agent in unipolar and bipolar treatment-resistant depression.
Alina Wilkowska +3 more
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Lamotrigine in the treatment of schizoaffective disorder [PDF]
, 1998 There is accumulating evidence for the efficacy of lamotrigine in the treatment of bipolar disorder, including bipolar depression, both as monotherapy and in combination with sodium valproate.
Grunze, Heinz +2 more
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New insights into the mechanisms and sites of action of lamotrigine [PDF]
, 2000 This study was aimed at investigating the effects of lamotrigine (LTG) on electrically evoked field excitatory postsynaptic potentials (fEPSP) and population spikes in the CA1 hippocampal region of guinea pigs.
Langosch, J. M. +3 more
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Modulation of calcium and potassium currents by lamotrigine [PDF]
, 1998 Actions of the new antiepileptic drug lamotrigine (LTG) were characterized using extracellular and whole cell patch clamp recordings from rat CAI and CA3 pyramidal cells in vitro.
Greene, Robert +4 more
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BMJ Neurology Open, 2020 Background Evidence suggests that lamotrigine could be effective in reducing aura frequency and duration. However, studies comparing lamotrigine to other, first-line prophylactic agents solely involving patients suffering from migraine with aura are ...
Francesco Janes +3 more
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