Results 11 to 20 of about 24,362 (263)

Lamotrigine serum concentrations as longitudinal biomarkers for seizure risk prediction in pregnant women with epilepsy: a secondary analysis of the EMPiRE study [PDF]

BMJ Neurology Open
Background Serum lamotrigine concentrations fall during pregnancy, and therapeutic drug monitoring is often used to guide dose adjustment. We do not know whether serial antenatal measurements improve prediction of seizure risk in pregnant women with ...
Shakila Thangaratinam, Javier Zamora, Teresa Pérez, John Allotey, Fatima Junaid, Valeria Rolle, María del Carmen Pardo   +6 more
doaj   +2 more sources

Action Tremor Associated with Lamotrigine Monotherapy [PDF]

Journal of Movement Disorders, 2010
Lamotrigine (LTG) is associated with a tremor when given in combination with valproic acid; however, a tremor associated with lamotrigine monotherapy is rare. Here, we report a case of positional and action tremor associated with lamotrigine use.
Ji-Hye Yang, Sung-Woo Chung, Joong-Seok Kim   +2 more
doaj   +2 more sources

Interactions Between Lamotrigine and Contraceptives – Communication Practises

BJPsych Open
Aims This audit assesses communication practices regarding interactions between lamotrigine and oral contraceptives in North West Sussex (NWS) Specialist Perinatal Mental Health Services (SPMHS). The predicted outcome includes increasing awareness about
Samina Monir, Cissy Atwine, Helen Hutchings, Michael Harris   +3 more
doaj   +2 more sources

Fosphenytoin may be effective in shortening the half-life of lamotrigine in case of overdose: a case report [PDF]

Journal of Medical Case Reports
Background This case study highlights the efficacy of fosphenytoin in managing cardiac arrest and seizures caused by lamotrigine overdose. While activated charcoal and sodium bicarbonate are typically recommended for lamotrigine overdose, alternative ...
Jun Sato, Shingo Ihara, Tsukasa Kuwana, Masao Sekimoto, Yuto Suzuki, Katsuhiro Nakagawa, Nobutaka Chiba, Takeshi Saito, Kosaku Kinoshita   +8 more
doaj   +2 more sources

Comparison of the Effects of Lamotrigine and Valproate on the Pentylenetetrazole-Induced Seizures and Behaviour of Immature Rats

Archives of Epilepsy, 2018
Objectives:Epileptics, especially children, are more prone to behavioural deficits. Epilepsy related factors, psychosocial problems, treatment side effects may aggravate such deficits.
Mehmet Fatih GÖL, Füsun Ferda ERDOĞAN, Ayşegül KÜÇÜK, Asuman GÖLGELİ   +3 more
doaj   +2 more sources

Case report: Progressive skin rash and lymphadenopathy associated with lamotrigine−valproic acid combination in a bipolar adolescent

Frontiers in Pharmacology, 2023
Background: Lamotrigine may cause severe skin reactions. There is a known interaction between lamotrigine and valproic acid with an increase in lamotrigine levels and lamotrigine toxicity risk.
Yingxu Duan, Fangxinrui Qiu, Jingyuan Zhou, Shiyu Liu, Die Zhao, Changjian Qiu   +5 more
doaj   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

Assessing efficacy and tolerability of lamotrigine (Sazar®) in therapy of female idiopathic generalized epilepsy: a multicenter study

Эпилепсия и пароксизмальные состояния, 2022
Background. Idiopathic generalized epilepsy (IGE) comprises 15–20% among all types of epilepsy. However, specifics of administration for lamotrigine in IGE in the Russian Federation remain poorly investigated, especially in female subjects.Objective: to ...
M. V. Barkhatov, I. S. Bakhtin, O. V. Belyaev, M. A. Yamin   +3 more
doaj   +1 more source

Lamotrigine, a Miscreant in Toxic Epidermal Necrolysis: A Rare Case Report [PDF]

, 2023
This case report is about a rural 39 years old female of Asian origin and laborer by profession who developed Toxic Epidermal Necrolysis (TEN) with lamotrigine.
Mahima MAKHIJA, Alka BANSAL, Deepak Raj SAKHNANI   +2 more
core   +1 more source

Liver dysfunction induced by systemic hypersensitivity reaction to lamotrigine: case report [PDF]

Clinical and Molecular Hepatology, 2015
Lamotrigine is an anticonvulsant drug used to treat partial and generalized seizure disorders. Hypersensitivity to lamotrigine usually causes mild symptoms such as fever, rash, and slight invasion of internal organs.
Sung Gyu Im, Sun Hong Yoo, Young Min Park, Sang Jin Lee, Sun Kyung Jang, Dong Ok Jeon, Hyo Jin Cho, Mi Jung Oh   +7 more
doaj   +1 more source